Human herpesvirus 6 in cerebrospinal fluid of patients infected with HIV: Frequency and clinical significance

Journal of Neurology Neurosurgery and Psychiatry

Volumn 67, Issue 6, 1999, Pages 789-792

  Bossolasco, Simona ^a   Marenzi, Roberta ^a   Dahl, Helena ^c   Vago, Luca ^b   Terreni, Maria Rosa ^a   Broccolo, Francesco ^a   Lazzarin, Adriano ^a   Linde, Annika ^c   Cinque, Paola ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cerebrospinal fluid; Cytomegalovirus; HIV infection; Human herpesvirus type 6

Indexed keywords

VIRUS DNA;

ARTICLE; BRAIN DISEASE; BRAIN TISSUE; CEREBROSPINAL FLUID; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENCEPHALITIS; HUMAN; HUMAN HERPESVIRUS 6; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; MAJOR CLINICAL STUDY; NEUROLOGIC DISEASE; NEUROPATHOLOGY; OPPORTUNISTIC INFECTION; PLASMA; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; SYSTEMIC DISEASE; VIRUS INFECTION; VIRUS REPLICATION;

EID: 0032721281     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.67.6.789     Document Type: Article

References (19)

1. Braun DK, Dominguez G, Pellet PE. Human herpesvirus 6 [review]. Clin Microbiol Rev 1997;10:521-67.
2. Kondo K, Nagafiji H, Hata A, et al. Association of human herpesvirus 6 infection of the central nervous system with recurrence of febrile convulsions. J Infect Dis 1993;167: 1197-200.
3. Suga S, Yoshikawa T, Asano Y, et al. Clinical and virological analyses of 21 infants with exanthem subitum (roseola infantum) and central nervous system complications. Ann Neurol 1993;33:597-603.
4. Caserta MT, Hall CB, Schnabel K, et al. Neuroinvasion and persistence of human herpesvirus 6 in children. J Infect Dis 1994;170:1586-9.
5. Drobyski W, Knox KK, Majewski D, et al. Brief report: fatal encephalitis due to variant B human herpesvirus-6 infection in a bone marrow-transplant recipient. N Engl J Med 1994;330:1356-60.
6. Wang F-Z, Linde A, Hägglund H, et al. Human herpesvirus-6 DNA in cerebrospinal fluid from allogeneic bone marrow transplant patients: does it have a clinical significance? Clin Infect Dis 1999;28:562-8.
7. Kimberlin DW, Whitley RJ. Human herpesvirus-6: neurological implications of a newly described herpesvirus [review]. J Neurovirol 1998;4:474-85.
8. Challoner PB, Kirsten TS, Parker JD, et al. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci USA 1995;92:7440-4.
9. Saito Y, Sharer LR, Dewhurst S, et al. Cellular localization of human herpesvirus-6 in the brain of children with AIDS encephalopathy. J Neurovirol 1995;1:30-9.
10. Knox KK, Carrigan DR. Active human herpesvirus infection of the central nervous system in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1995;9: 69-73.
11. Cinque P, Vago L, Dahl H, et al. Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus-associated opportunistic diseases of the central nervous system in HIV-infected patients. AIDS 1996;10:951-8.
12. Liedtke W, Malessa R, Faustmann PM, et al. Human herpesvirus-6 polymerase chain reaction findings in human immunodeficiency virus associated neurological disease and multiple sclerosis. J Neurovirol 1995;1:253-8.
13. Yalcin S, Karpazoglu T, Suleymanlar G, et al. Human herpesvirus 6 and human herpesvirus 7 infections in renal transplant recipients and healthy adults in Turkey. Arch Virol 1994;136:183-90.
14. Cinque P, Vago L, Marenzi R, et al. Herpes simplex viruses infections of the nervous system in human immunodeficiency virus-infected patients: clinical management by polymerase chain reaction analysis of cerebrospinal fluid. Clin Infect Dis 1998;27:303-9.
15. Cinque P, Bossolasco S, Vago L, et al. Varicella-zoster virus (VZV) DNA in cerebrospinal fluid of patients infected with human immunodeficiency virus: VZV disease of the central nervous system or subclinical reactivation of VZV infection? Clin Infect Dis 1997;25:634-9.
16. Hall CB, Caserta MT, Schnabel KC, et al. Persistence of human herpesvirus 6 according to site and variant: possible greater neurotropism of variant A. Clin Infect Dis 1998;26: 132-7.
17. Herbein G, Strasswimmer J, Altieri M, et al. Longitudinal study of human herpesvirus 6 infection in organ transplant recipients. Clin Infect Dis 1996;22:171-3.
18. DesJardin JA, Gibbons L, Cho E, et al. Human herpesvirus 6 reactivation is associated with cytomegalovirus infection and syndromes in kidney transplant recipients at risk for primary cytomegalovirus infection. J Infect Dis 1998;178: 1783-6.
19. Anderson RA, Liu DX, Gompels UA. Definition of a human herpesvirus 6 β herpesvirus-specific domain in glycoprotein gH that governs interaction with glycoprotein gL: substitution of human cytomegalovirus glycoproteins permits group-specific complex formation. Virology 1996; 217:517-26.