Novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene

Journal of Human Genetics

Volumn 44, Issue 6, 1999, Pages 416-418

  Mitsuyasu, Hiroshi ^a   Ozawa, Hidetoshi ^a   Takeda, Yasuhiko ^a   Fukumaki, Yasuyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Dopamine D4 receptor gene; Polymorphisms; Promoter; RFLP

Indexed keywords

DNA; DOPAMINE 4 RECEPTOR;

AFFECTIVE NEUROSIS; ALCOHOLISM; ARTICLE; ATTENTION DEFICIT DISORDER; CELL SPECIFICITY; CONTROLLED STUDY; DNA FLANKING REGION; DNA POLYMORPHISM; DNA SEQUENCE; GENE FREQUENCY; GENOTYPE; GILLES DE LA TOURETTE SYNDROME; HUMAN; HUMAN CELL; HUMAN TISSUE; JAPAN; MENTAL DISEASE; POLYMERASE CHAIN REACTION; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCHIZOPHRENIA; SUBSTANCE ABUSE;

EID: 0032720407     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380050191     Document Type: Article

References (5)

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3. Okuyama Y, lshiguro H, Toru M, Arinami T (1999) A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia. Biochem Biophys Res Commun 258:292-295
4. Seeman P, Guan H-C, Van Tol HHM (1993) Dopamine D4 receptors elevated in schizophrenia. Nature 365:441-445
5. Stefanis NC, Bresnick JN, Kerwin RW, Schofield WN, McAllister G (1998) Elevation of D4 dopamine receptor mRNA in postmortem schizophrenic brain. Brain Res Mol Brain Res 53:112-119