Physico-chemical characterisation of the modifications I and II of (R,S) propranolol hydrochloride: Solubility and dissolution studies

Journal of Pharmaceutical and Biomedical Analysis

Volumn 21, Issue 2, 1999, Pages 299-309

  Bartolomei, Monica ^a   Bertocchi, Paola ^a   Cotta Ramusino, Marina ^a   Santucci, Nora ^b   Valvo, Luisa ^a  

^a Laboratorio di Chimica del Farmaco   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Equilibrium solubility; Infrared spectroscopy; Intrinsic dissolution; Physical stability; Polymorphism; Propranolol hydrochloride

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; PROPRANOLOL;

ANALYTIC METHOD; ARTICLE; DRUG SOLUBILITY; FOURIER TRANSFORMATION; INFRARED SPECTROSCOPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; THERMAL ANALYSIS; X RAY DIFFRACTION;

CRYSTALLIZATION; DRUG STABILITY; PROPRANOLOL; SOLUBILITY; SOLUTIONS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STEREOISOMERISM; X-RAY DIFFRACTION;

EID: 0032720026     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(99)00128-4     Document Type: Article

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