메뉴 건너뛰기




Volumn 2, Issue 3, 1999, Pages 139-149

Paracetamol revisited: A review of the pharmacokinetics and pharmacodynamics

Author keywords

Acetaminophen; Analgesics; Antipy retics; Paracetamol; Pharmacodynamics; Pharmacokinetics

Indexed keywords

ACETYLCYSTEINE; CODEINE; DEXTROPROPOXYPHENE; DICLOFENAC; KETOPROFEN; KETOROLAC; MORPHINE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PROPACETAMOL;

EID: 0032719186     PISSN: 13660071     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1366-0071(99)80006-0     Document Type: Article
Times cited : (67)

References (75)
  • 1
    • 85119790985 scopus 로고    scopus 로고
    • Clinical guidelines for the use of non-steroidal anti-inflammatory drugs in the perioperative period 1998 Royal College of Anaesthetists London
    • (1998)
  • 2
    • 0025275548 scopus 로고
    • Effects of acetylsalycylic acid and paracetamol alone and in combination on prostanoid synthesis in man
    • Bippi H Frohich JC Effects of acetylsalycylic acid and paracetamol alone and in combination on prostanoid synthesis in man Br J Clin Pharmacol 29 1990 305 310
    • (1990) Br J Clin Pharmacol , vol.29 , pp. 305-310
    • Bippi, H1    Frohich, JC2
  • 3
    • 0025166583 scopus 로고
    • Effects of nonsteroidal anti-inflammatory drugs and prednisolone on synovial fluid white cells, prostaglandin E2, leukotriene B4 and cyclic AMP in patients with rheumatoid arthritis
    • Seppala E Nissila E Isomaki H Wuorela H Effects of nonsteroidal anti-inflammatory drugs and prednisolone on synovial fluid white cells, prostaglandin E2, leukotriene B4 and cyclic AMP in patients with rheumatoid arthritis Scand J Rheumatol 19 1990 71 75
    • (1990) Scand J Rheumatol , vol.19 , pp. 71-75
    • Seppala, E1    Nissila, E2    Isomaki, H3    Wuorela, H4
  • 4
    • 0025804290 scopus 로고
    • Aspirin like drugs may block pain independently of prostaglandin synthesis inhibition
    • Brune K Beck WS Geisslinger G Menzel-Soglowek S Aspirin like drugs may block pain independently of prostaglandin synthesis inhibition Experientia (Basel) 47 1991 257 261
    • (1991) Experientia (Basel) , vol.47 , pp. 257-261
    • Brune, K1    Beck, WS2    Geisslinger, G3    Menzel-Soglowek, S4
  • 5
    • 0020319686 scopus 로고
    • Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla
    • Brucchausen FV Baumann J Inhibitory actions of desacetylation products of phenacetin and paracetamol on prostaglandin synthetases in neuronal and glial cell lines and rat renal medulla Life Sci 30 1982 1783 1791
    • (1982) Life Sci , vol.30 , pp. 1783-1791
    • Brucchausen, FV1    Baumann, J2
  • 6
    • 0026022639 scopus 로고
    • Antinociceptive effect of paracetamol in rats is partly dependent on spinal serotonergic systems
    • Tjolsen A Lund A Hole K Antinociceptive effect of paracetamol in rats is partly dependent on spinal serotonergic systems Eur J Pharmacol 193 1991 193 201
    • (1991) Eur J Pharmacol , vol.193 , pp. 193-201
    • Tjolsen, A1    Lund, A2    Hole, K3
  • 7
    • 0029124268 scopus 로고
    • Evidence of a central antinociceptive effect of paracetamol involving spinal 5-HT3 receptors
    • Pelissier T Alloui A Paeile C Eschalier A Evidence of a central antinociceptive effect of paracetamol involving spinal 5-HT3 receptors Neuroreport 6 11 1995 1546 1548
    • (1995) Neuroreport , vol.6 , Issue.11 , pp. 1546-1548
    • Pelissier, T1    Alloui, A2    Paeile, C3    Eschalier, A4
  • 8
    • 0030426275 scopus 로고    scopus 로고
    • Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence
    • Pelissier T Alloui A Caussade F Dubray C Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence J Pharmacol Exp Ther 278 1 1996 8 14
    • (1996) J Pharmacol Exp Ther , vol.278 , Issue.1 , pp. 8-14
    • Pelissier, T1    Alloui, A2    Caussade, F3    Dubray, C4
  • 9
    • 0022229067 scopus 로고
    • Acetylsalicylic acid, paracetamol and morphine inhibit behavioral responses to intrathecally administered substance P or capsaicin
    • Hunskaar S Fasmer OB Holke K Acetylsalicylic acid, paracetamol and morphine inhibit behavioral responses to intrathecally administered substance P or capsaicin Life Sci 37 1985 1835 1841
    • (1985) Life Sci , vol.37 , pp. 1835-1841
    • Hunskaar, S1    Fasmer, OB2    Holke, K3
  • 10
    • 0028321670 scopus 로고
    • Acetominophen blocks spinal hyperalgesia induced by NMDA and substance P
    • Bjorkman R Hallman KM Hender T Henning M Acetominophen blocks spinal hyperalgesia induced by NMDA and substance P Pain 57 1994 259 264
    • (1994) Pain , vol.57 , pp. 259-264
    • Bjorkman, R1    Hallman, KM2    Hender, T3    Henning, M4
  • 11
    • 0017363410 scopus 로고
    • Pharmacokinetics of paracetamol after intravenous and oral administration
    • Rawlins MD Henderson DB Hijab AR Pharmacokinetics of paracetamol after intravenous and oral administration Eur J Clin Pharmacol 11 4 1977 283 286
    • (1977) Eur J Clin Pharmacol , vol.11 , Issue.4 , pp. 283-286
    • Rawlins, MD1    Henderson, DB2    Hijab, AR3
  • 12
    • 1842328132 scopus 로고
    • Acetominophen II.A comparison of the physiological availability of different commercial dosage forms
    • McGilveray IJ Mattock GL Fooks JR Jordan N Acetominophen II.A comparison of the physiological availability of different commercial dosage forms Can J Pharm Sci 6 1971 38 42
    • (1971) Can J Pharm Sci , vol.6 , pp. 38-42
    • McGilveray, IJ1    Mattock, GL2    Fooks, JR3    Jordan, N4
  • 13
    • 0024454593 scopus 로고
    • Single dose availability of acetominophen following oral absorption
    • Borin MT Ayres JW Single dose availability of acetominophen following oral absorption Int J Pharm 54 1989 199 209
    • (1989) Int J Pharm , vol.54 , pp. 199-209
    • Borin, MT1    Ayres, JW2
  • 14
    • 0026594498 scopus 로고
    • Single dose pharmacokinetics of ibuprofen and acetaminophen in febrile children
    • Brown RD Wilson JT Kearns GL Eichler VF Single dose pharmacokinetics of ibuprofen and acetaminophen in febrile children J Clin Pharmacol 32 1992 231 241
    • (1992) J Clin Pharmacol , vol.32 , pp. 231-241
    • Brown, RD1    Wilson, JT2    Kearns, GL3    Eichler, VF4
  • 15
    • 0031006536 scopus 로고    scopus 로고
    • Comparative bioavailability of aspirin and paracetamol following single dose administration of soluble and plain tablets
    • Muir N Nichols JD Stillings MR Sykes J Comparative bioavailability of aspirin and paracetamol following single dose administration of soluble and plain tablets Curr Med Res Opin 13 9 1997 491 500
    • (1997) Curr Med Res Opin , vol.13 , Issue.9 , pp. 491-500
    • Muir, N1    Nichols, JD2    Stillings, MR3    Sykes, J4
  • 16
    • 0031952048 scopus 로고    scopus 로고
    • Intraindividual variability of paracetamol absorption kinetics after a semi-solid meal in healthy volunteers
    • Paintaud G Thibault P Queneau PE Magnette J Intraindividual variability of paracetamol absorption kinetics after a semi-solid meal in healthy volunteers Eur J Clin Pharmacol 53 5 1998 355 359
    • (1998) Eur J Clin Pharmacol , vol.53 , Issue.5 , pp. 355-359
    • Paintaud, G1    Thibault, P2    Queneau, PE3    Magnette, J4
  • 17
    • 0031980882 scopus 로고    scopus 로고
    • The effect of food on bromfenac, naproxen sodium, and acetaminophen in postoperative pain after orthopedic surgery
    • Forbes JA Sandberg RA Bood-Bjorklund L The effect of food on bromfenac, naproxen sodium, and acetaminophen in postoperative pain after orthopedic surgery Pharmacotherapy 18 3 1998 492 503
    • (1998) Pharmacotherapy , vol.18 , Issue.3 , pp. 492-503
    • Forbes, JA1    Sandberg, RA2    Bood-Bjorklund, L3
  • 18
    • 17444436925 scopus 로고    scopus 로고
    • Variability of concentrations after rectal paracetamol [Letter]
    • Anderson BJ Monteleone J Holford NH Variability of concentrations after rectal paracetamol [Letter] Paediatr Anaesth 8 3 1998 274
    • (1998) Paediatr Anaesth , vol.8 , Issue.3 , pp. 274
    • Anderson, BJ1    Monteleone, J2    Holford, NH3
  • 19
    • 0024412853 scopus 로고
    • Paracetamol suppositories: a comparative study
    • Cullen S Kenny D Ward OC Sabra K Paracetamol suppositories: a comparative study Arch Dis Child 64 1989 1504 1505
    • (1989) Arch Dis Child , vol.64 , pp. 1504-1505
    • Cullen, S1    Kenny, D2    Ward, OC3    Sabra, K4
  • 20
    • 0031664872 scopus 로고    scopus 로고
    • Is one paracetamol suppository of 1000 mg bioequivalent with two suppositories of 500 mg
    • Narvanen T Halsas M Smal J Marvola M Is one paracetamol suppository of 1000 mg bioequivalent with two suppositories of 500 mg Eur J Drug Metab Pharmacokinet 23 2 1998 203 206
    • (1998) Eur J Drug Metab Pharmacokinet , vol.23 , Issue.2 , pp. 203-206
    • Narvanen, T1    Halsas, M2    Smal, J3    Marvola, M4
  • 21
  • 22
    • 0031725732 scopus 로고    scopus 로고
    • Relative bioavailability and plasma paracetamol profiles of Panadol suppositories in children
    • Coulthard KP Nielson HW Schroder M Covino A Relative bioavailability and plasma paracetamol profiles of Panadol suppositories in children J Paediatr Child Health 34 5 1998 425 431
    • (1998) J Paediatr Child Health , vol.34 , Issue.5 , pp. 425-431
    • Coulthard, KP1    Nielson, HW2    Schroder, M3    Covino, A4
  • 23
    • 0028675375 scopus 로고
    • Relative bioavailability of paracetamol in suppository preparation in comparison to tablets
    • Blume H Ali SL Elze M Kramer J Relative bioavailability of paracetamol in suppository preparation in comparison to tablets Arzneimittelforschung 44 12 1994 1333 1338
    • (1994) Arzneimittelforschung , vol.44 , Issue.12 , pp. 1333-1338
    • Blume, H1    Ali, SL2    Elze, M3    Kramer, J4
  • 24
    • 0028884884 scopus 로고
    • Plasma concentrations after high-dose (45 mg/kg) rectal acetaminophen in children
    • Montgomery CJ McCormack JP Reichert CC Marsland CP Plasma concentrations after high-dose (45 mg/kg) rectal acetaminophen in children Can J Anaesth 42 11 1995 982 986
    • (1995) Can J Anaesth , vol.42 , Issue.11 , pp. 982-986
    • Montgomery, CJ1    McCormack, JP2    Reichert, CC3    Marsland, CP4
  • 25
    • 0029952502 scopus 로고    scopus 로고
    • Plasma concentration profiles after pre-operative rectal administration of a solution of paracetamol in children
    • Kolloffel WJ Driessen FG Goldhoorn PB Plasma concentration profiles after pre-operative rectal administration of a solution of paracetamol in children Pharm World Sci 18 3 1996 105 108
    • (1996) Pharm World Sci , vol.18 , Issue.3 , pp. 105-108
    • Kolloffel, WJ1    Driessen, FG2    Goldhoorn, PB3
  • 26
    • 0030690271 scopus 로고    scopus 로고
    • Plasma concentrations after rectal administration of acetaminophen in preterm neonates
    • Lin YC Sussman HH Benitz WE Plasma concentrations after rectal administration of acetaminophen in preterm neonates Paediatr Anaesth 7 1997 457 459
    • (1997) Paediatr Anaesth , vol.7 , pp. 457-459
    • Lin, YC1    Sussman, HH2    Benitz, WE3
  • 27
    • 0030842616 scopus 로고    scopus 로고
    • Twenty-four-hour pharmacokinetics of rectal acetaminophen in children
    • Birmingham PK Tobin MJ Henthorn TK Fisher DM Twenty-four-hour pharmacokinetics of rectal acetaminophen in children Anesthesiology 87 2 1997 244 252
    • (1997) Anesthesiology , vol.87 , Issue.2 , pp. 244-252
    • Birmingham, PK1    Tobin, MJ2    Henthorn, TK3    Fisher, DM4
  • 28
    • 0029445433 scopus 로고
    • Pharmacokinetics of rectal paracetamol after major surgery in children
    • Anderson BJ Woolard GA Holford NHG Pharmacokinetics of rectal paracetamol after major surgery in children Paediatr Anaesth 5 1995 237 242
    • (1995) Paediatr Anaesth , vol.5 , pp. 237-242
    • Anderson, BJ1    Woolard, GA2    Holford, NHG3
  • 29
    • 0027225216 scopus 로고
    • A placebo-controlled model for assaying systemic analgesics in children
    • Schachtel BP Thoden WR A placebo-controlled model for assaying systemic analgesics in children J Clin Pharmacol Ther 53 1993 593 601
    • (1993) J Clin Pharmacol Ther , vol.53 , pp. 593-601
    • Schachtel, BP1    Thoden, WR2
  • 30
    • 0032560410 scopus 로고    scopus 로고
    • Pain relief in children. Doing the simple things better [Editorial]
    • Zacharias M Watts D Pain relief in children. Doing the simple things better [Editorial] BMJ 316 7144 1998 1552
    • (1998) BMJ , vol.316 , Issue.7144 , pp. 1552
    • Zacharias, M1    Watts, D2
  • 31
    • 0027725713 scopus 로고
    • Pharmacokinetics of paracetamol in the neonate and infant after administration of propacetamol chlorhydrate
    • Autret E Dutertre JP Breteau M Pharmacokinetics of paracetamol in the neonate and infant after administration of propacetamol chlorhydrate Dev Pharmacol Ther 20 1993 129 134
    • (1993) Dev Pharmacol Ther , vol.20 , pp. 129-134
    • Autret, E1    Dutertre, JP2    Breteau, M3
  • 32
    • 0004058229 scopus 로고    scopus 로고
    • Paracetamol (acetaminophen). A Critical Bibliographic Review
    • Prescott LF Paracetamol (acetaminophen). A Critical Bibliographic Review 1st edition 1996 Taylor and Francis London
    • (1996)
    • Prescott, LF1
  • 33
    • 0029006554 scopus 로고
    • The morphine-sparing effect of propacetamol in orthopedic postoperative pain
    • Delbos A Boccard E The morphine-sparing effect of propacetamol in orthopedic postoperative pain J Pain Symptom Manage 10 4 1995 279 286
    • (1995) J Pain Symptom Manage , vol.10 , Issue.4 , pp. 279-286
    • Delbos, A1    Boccard, E2
  • 34
    • 0026774994 scopus 로고
    • Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children
    • Kelley MT Watson PD Edge JH Cox S Pharmacokinetics and pharmacodynamics of ibuprofen isomers and acetaminophen in febrile children J Clin Pharmacol Ther 52 1992 181 189
    • (1992) J Clin Pharmacol Ther , vol.52 , pp. 181-189
    • Kelley, MT1    Watson, PD2    Edge, JH3    Cox, S4
  • 35
    • 84994927188 scopus 로고
    • Pharmacokinetics and antipyretic effects of an injectable prodrug of paracetamol (propacetamol) in children
    • Granry JC Rod B Boccard E Hermann P Pharmacokinetics and antipyretic effects of an injectable prodrug of paracetamol (propacetamol) in children Pediatr Anaesth 2 1992 291 295
    • (1992) Pediatr Anaesth , vol.2 , pp. 291-295
    • Granry, JC1    Rod, B2    Boccard, E3    Hermann, P4
  • 36
    • 0031671563 scopus 로고    scopus 로고
    • Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children
    • Anderson BJ Holford NHG Woollard GA Chan PLS Paracetamol plasma and cerebrospinal fluid pharmacokinetics in children Br J Clin Pharmacol 46 1998 237 243
    • (1998) Br J Clin Pharmacol , vol.46 , pp. 237-243
    • Anderson, BJ1    Holford, NHG2    Woollard, GA3    Chan, PLS4
  • 37
    • 0026653542 scopus 로고
    • Plasma and cerebrospinal fluid concentrations of paracetamol after a single intravenous dose of paracetamol
    • Bannwarth B Netter P Lapicque F Gillet P Plasma and cerebrospinal fluid concentrations of paracetamol after a single intravenous dose of paracetamol Br J Clin Pharmacol 34 1992 79 81
    • (1992) Br J Clin Pharmacol , vol.34 , pp. 79-81
    • Bannwarth, B1    Netter, P2    Lapicque, F3    Gillet, P4
  • 38
    • 0018163621 scopus 로고
    • Aspirin versus acetominophen: A comparative view
    • Rumack BH Aspirin versus acetominophen: A comparative view Pediatrics 62 1978 943 946
    • (1978) Pediatrics , vol.62 , pp. 943-946
    • Rumack, BH1
  • 40
    • 0002052721 scopus 로고    scopus 로고
    • Analgesic-antipyretic and anti-inflammatory agents
    • Insel PA Analgesic-antipyretic and anti-inflammatory agents Hardman JG Limbird LE Goodman and Gilman's The Pharmacological Basis of Therapeutics 1996 McGraw-Hill London 631 633
    • (1996) , pp. 631-633
    • Insel, PA1
  • 41
    • 0029783351 scopus 로고    scopus 로고
    • Human metabolism of paracetamol (acetaminophen) at different dose levels
    • Steventon GB Mitchell SC Waring RH Human metabolism of paracetamol (acetaminophen) at different dose levels Drug Metab Drug Interact 13 2 1996 111 117
    • (1996) Drug Metab Drug Interact , vol.13 , Issue.2 , pp. 111-117
    • Steventon, GB1    Mitchell, SC2    Waring, RH3
  • 42
    • 0019430214 scopus 로고
    • Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment
    • Rumack BH Peterson RC Koch GG Amara IA Acetaminophen overdose. 662 cases with evaluation of oral acetylcysteine treatment Arch Intern Med 141 1981 380 385
    • (1981) Arch Intern Med , vol.141 , pp. 380-385
    • Rumack, BH1    Peterson, RC2    Koch, GG3    Amara, IA4
  • 43
    • 0030706049 scopus 로고    scopus 로고
    • Acetominophen use in children: more is not better
    • Heubi JE Bien JP Acetominophen use in children: more is not better J Pediatr 130 1997 175 177
    • (1997) J Pediatr , vol.130 , pp. 175-177
    • Heubi, JE1    Bien, JP2
  • 44
    • 0021263980 scopus 로고
    • Acetaminophen overdose in young children
    • Rumack BH Acetaminophen overdose in young children Am J Dis Child 138 1984 428 433
    • (1984) Am J Dis Child , vol.138 , pp. 428-433
    • Rumack, BH1
  • 45
    • 0031724049 scopus 로고    scopus 로고
    • What we don't know about paracetamol in children
    • Anderson BJ What we don't know about paracetamol in children Paediatr Anaesth 8 1998 451 460
    • (1998) Paediatr Anaesth , vol.8 , pp. 451-460
    • Anderson, BJ1
  • 46
    • 0025826953 scopus 로고
    • Paracetamol poisoning in children and hepatotoxicity
    • Penna A Buchanan N Paracetamol poisoning in children and hepatotoxicity Br J Clin Pharmacol 32 1991 143 149
    • (1991) Br J Clin Pharmacol , vol.32 , pp. 143-149
    • Penna, A1    Buchanan, N2
  • 47
    • 0021125256 scopus 로고
    • Paracetamol metabolites in the neonate following maternal overdose
    • Roberts I Robinson MJ Mughal MZ Ratcliffe JG Paracetamol metabolites in the neonate following maternal overdose Br J Clin Pharmacol 18 1984 201 206
    • (1984) Br J Clin Pharmacol , vol.18 , pp. 201-206
    • Roberts, I1    Robinson, MJ2    Mughal, MZ3    Ratcliffe, JG4
  • 48
    • 1642276066 scopus 로고
    • Evidence for the involvement on N-acetyl-p-quinoneimine in acetaminophen poisoning
    • Miner DJ Kissinger PT Evidence for the involvement on N-acetyl-p-quinoneimine in acetaminophen poisoning Ann Rev Pharmacol Toxicol 12 1983 251
    • (1983) Ann Rev Pharmacol Toxicol , vol.12 , pp. 251
    • Miner, DJ1    Kissinger, PT2
  • 49
    • 0023124537 scopus 로고
    • Dose dependent pharmacokinetics of acetaminophen: Evidence of glutathione depletion in humans
    • Slattery JT Wilson JM Kalhorn TF Dose dependent pharmacokinetics of acetaminophen: Evidence of glutathione depletion in humans Clin Pharmacol Ther 41 1987 413 418
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 413-418
    • Slattery, JT1    Wilson, JM2    Kalhorn, TF3
  • 50
    • 0021137295 scopus 로고
    • Acetaminophen accumulation in pediatric patients after repeated therapeutic doses
    • Nahata MC Powell DA Durrell DE Acetaminophen accumulation in pediatric patients after repeated therapeutic doses Eur J Clin Pharmacol 27 1984 57 59
    • (1984) Eur J Clin Pharmacol , vol.27 , pp. 57-59
    • Nahata, MC1    Powell, DA2    Durrell, DE3
  • 51
    • 0027456764 scopus 로고
    • Paracetamol: When, why and how much
    • Shann F Paracetamol: When, why and how much J Paediatr Child Health 29 1993 84 85
    • (1993) J Paediatr Child Health , vol.29 , pp. 84-85
    • Shann, F1
  • 52
    • 0020954033 scopus 로고
    • Pediatric dosing of acetaminophen
    • Temple AR Pediatric dosing of acetaminophen Paediatr Pharmacol 3 1983 321 327
    • (1983) Paediatr Pharmacol , vol.3 , pp. 321-327
    • Temple, AR1
  • 53
    • 0030687996 scopus 로고    scopus 로고
    • Outcome of acetominophen overdose in pediatric patients and factors contributing to hepatotoxicity
    • Rivera-Penera T Gugig R Davis J McDiarmid S Outcome of acetominophen overdose in pediatric patients and factors contributing to hepatotoxicity J Paediatr 130 1997 300 304
    • (1997) J Paediatr , vol.130 , pp. 300-304
    • Rivera-Penera, T1    Gugig, R2    Davis, J3    McDiarmid, S4
  • 54
    • 0015733053 scopus 로고
    • Acetaminophen induced hepatic necrosis IV. Protective role of glutathione
    • Mitchell JR Jollow DJ Potter WZ Gillette JR Acetaminophen induced hepatic necrosis IV. Protective role of glutathione J Pharmacol Exp Ther 187 1973 211 217
    • (1973) J Pharmacol Exp Ther , vol.187 , pp. 211-217
    • Mitchell, JR1    Jollow, DJ2    Potter, WZ3    Gillette, JR4
  • 55
    • 0031902252 scopus 로고    scopus 로고
    • Mechanism of action and value of N-acetylcysteine in the treatment of early and late acetaminophen poisoning: A critical review
    • Jones AL Mechanism of action and value of N-acetylcysteine in the treatment of early and late acetaminophen poisoning: A critical review J Toxicol Clin Toxicol 36 4 1998 277 285
    • (1998) J Toxicol Clin Toxicol , vol.36 , Issue.4 , pp. 277-285
    • Jones, AL1
  • 56
    • 0030793658 scopus 로고    scopus 로고
    • 1996 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System
    • Litovitz TL Smilkstein M Felberg L Klein-Schwartz W 1996 Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System Am J Emerg Med 15 1997 447 500
    • (1997) Am J Emerg Med , vol.15 , pp. 447-500
    • Litovitz, TL1    Smilkstein, M2    Felberg, L3    Klein-Schwartz, W4
  • 57
    • 0018651356 scopus 로고
    • Intravenous N-acetylcysteine: The treatment of choice for paracetamol poisoning
    • Prescott LF Illingworth RN Critchley JA Stewart MJ Intravenous N-acetylcysteine: The treatment of choice for paracetamol poisoning BMJ 2 1979 1097 1100
    • (1979) BMJ , vol.2 , pp. 1097-1100
    • Prescott, LF1    Illingworth, RN2    Critchley, JA3    Stewart, MJ4
  • 58
    • 0024262737 scopus 로고
    • Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose: Analysis of the national multicenter study (1976–1985)
    • Smilkstein MJ Knapp GL Kulig KW Rumack BH Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose: Analysis of the national multicenter study (1976–1985) N Engl J Med 319 1988 1557 1562
    • (1988) N Engl J Med , vol.319 , pp. 1557-1562
    • Smilkstein, MJ1    Knapp, GL2    Kulig, KW3    Rumack, BH4
  • 59
    • 0025946778 scopus 로고
    • Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: A prospective controlled trial
    • Keays R Harrison PM Wendon JA Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: A prospective controlled trial BMJ 303 1991 1026 1029
    • (1991) BMJ , vol.303 , pp. 1026-1029
    • Keays, R1    Harrison, PM2    Wendon, JA3
  • 60
    • 0028071108 scopus 로고
    • Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis
    • Jones AL Bangash IH Bouchier IA Hayes PC Portal and systemic haemodynamic action of N-acetylcysteine in patients with stable cirrhosis Gut 35 1994 1290 1293
    • (1994) Gut , vol.35 , pp. 1290-1293
    • Jones, AL1    Bangash, IH2    Bouchier, IA3    Hayes, PC4
  • 61
    • 0030734342 scopus 로고    scopus 로고
    • Equivalent antipyretic activity of ibuprofen and paracetamol in febrile children
    • Vauzelle-Kervroedan F D'Athis P Pariente-Khayat A Debregeas S Equivalent antipyretic activity of ibuprofen and paracetamol in febrile children J Pediatr 131 5 1997 683 687
    • (1997) J Pediatr , vol.131 , Issue.5 , pp. 683-687
    • Vauzelle-Kervroedan, F1    D'Athis, P2    Pariente-Khayat, A3    Debregeas, S4
  • 62
    • 0030046128 scopus 로고    scopus 로고
    • Comparing efficacy and tolerability of ibuprofen and paracetamol in fever
    • McIntyre J Hull D Comparing efficacy and tolerability of ibuprofen and paracetamol in fever Arch Dis Child 74 2 1996 164 167
    • (1996) Arch Dis Child , vol.74 , Issue.2 , pp. 164-167
    • McIntyre, J1    Hull, D2
  • 63
    • 0031218155 scopus 로고    scopus 로고
    • The efficacy of nonopioid analgesics for postoperative dental pain: A meta-analysis
    • Ahmad N Grad HA Haas DA Aronson KJ The efficacy of nonopioid analgesics for postoperative dental pain: A meta-analysis Anesthesia Progress 44 4 1997 119 126
    • (1997) Anesthesia Progress , vol.44 , Issue.4 , pp. 119-126
    • Ahmad, N1    Grad, HA2    Haas, DA3    Aronson, KJ4
  • 64
    • 0030987758 scopus 로고    scopus 로고
    • Acetaminophen or ketorolac for post myringotomy pain in children? A prospective, double-blinded comparison
    • Bean-Lijewski JD Stinson JC Acetaminophen or ketorolac for post myringotomy pain in children? A prospective, double-blinded comparison Paediatr Anaesth 7 2 1997 131 137
    • (1997) Paediatr Anaesth , vol.7 , Issue.2 , pp. 131-137
    • Bean-Lijewski, JD1    Stinson, JC2
  • 65
    • 9344251686 scopus 로고    scopus 로고
    • A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children
    • Bertin L Pons G D'Athis P Duhamel JF A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children Fundam Clin Pharmacol 10 4 1996 387 392
    • (1996) Fundam Clin Pharmacol , vol.10 , Issue.4 , pp. 387-392
    • Bertin, L1    Pons, G2    D'Athis, P3    Duhamel, JF4
  • 66
    • 0029823647 scopus 로고    scopus 로고
    • Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination
    • Montgomery JE Sutherland CJ Kestin IG Sneyd JR Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination Br J Anaesth 77 4 1996 445 447
    • (1996) Br J Anaesth , vol.77 , Issue.4 , pp. 445-447
    • Montgomery, JE1    Sutherland, CJ2    Kestin, IG3    Sneyd, JR4
  • 67
    • 9844233713 scopus 로고    scopus 로고
    • Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol
    • Li Wan Po A Zhang WY Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol BMJ 315 1997 1565 1571
    • (1997) BMJ , vol.315 , pp. 1565-1571
    • Li Wan, Po A1    Zhang, WY2
  • 68
    • 0029832635 scopus 로고    scopus 로고
    • Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain — a meta-analysis
    • Zhang WY Li Wan Po A Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain — a meta-analysis J Clin Pharm Ther 21 4 1996 261 282
    • (1996) J Clin Pharm Ther , vol.21 , Issue.4 , pp. 261-282
    • Zhang, WY1    Li Wan, Po A2
  • 69
    • 0029787774 scopus 로고    scopus 로고
    • Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: A systematic review
    • De Craen AJ Di Giulio G Lampe-Schoenmaeckers JE Kessels AG Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: A systematic review BMJ 313 7053 1996 321 325
    • (1996) BMJ , vol.313 , Issue.7053 , pp. 321-325
    • De Craen, AJ1    Di Giulio, G2    Lampe-Schoenmaeckers, JE3    Kessels, AG4
  • 70
    • 0031875656 scopus 로고    scopus 로고
    • Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain
    • Schug SA Sidebotham DA McGuinnety M Thomas J Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain Anesth Analg 87 2 1998 368 372
    • (1998) Anesth Analg , vol.87 , Issue.2 , pp. 368-372
    • Schug, SA1    Sidebotham, DA2    McGuinnety, M3    Thomas, J4
  • 71
    • 6844250965 scopus 로고    scopus 로고
    • Efficacy of propacetamol in the treatment of postoperative pain
    • Peduto VA Ballabio M Stefanini S Efficacy of propacetamol in the treatment of postoperative pain Acta Anaesthesiol Scand 42 3 1998 293 298
    • (1998) Acta Anaesthesiol Scand , vol.42 , Issue.3 , pp. 293-298
    • Peduto, VA1    Ballabio, M2    Stefanini, S3
  • 72
    • 0031132499 scopus 로고    scopus 로고
    • Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery
    • Fletcher D Negre I Barbin C Francois A Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery Can J Anaesth 44 5 1997 479 485
    • (1997) Can J Anaesth , vol.44 , Issue.5 , pp. 479-485
    • Fletcher, D1    Negre, I2    Barbin, C3    Francois, A4
  • 73
    • 0032897894 scopus 로고    scopus 로고
    • Analgesic efficacy of paracetamol and diclofenac in children receiving PCA morphine
    • Morton NS O'Brien K Analgesic efficacy of paracetamol and diclofenac in children receiving PCA morphine Br J Anaesth 82 1999 715 717
    • (1999) Br J Anaesth , vol.82 , pp. 715-717
    • Morton, NS1    O'Brien, K2
  • 74
    • 0032975775 scopus 로고    scopus 로고
    • A double blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: Analgesic efficiency and tolerability after gynaecological surgery
    • Varrassi G Marinangeli F Agro F Aloe L A double blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: Analgesic efficiency and tolerability after gynaecological surgery Anaesth Analg 88 1999 611 616
    • (1999) Anaesth Analg , vol.88 , pp. 611-616
    • Varrassi, G1    Marinangeli, F2    Agro, F3    Aloe, L4
  • 75
    • 0026546980 scopus 로고
    • Analgesic efficacy of immediate and sustained release paracetamol and plasma concentration of paracetamol. Double blind, placebo-controlled evaluation using painful laser stimulation
    • Nielsen JC Bjerring P Arendt-Nielsen L Petterson KJ Analgesic efficacy of immediate and sustained release paracetamol and plasma concentration of paracetamol. Double blind, placebo-controlled evaluation using painful laser stimulation Eur J Clin Pharm 42 3 1992 261 264
    • (1992) Eur J Clin Pharm , vol.42 , Issue.3 , pp. 261-264
    • Nielsen, JC1    Bjerring, P2    Arendt-Nielsen, L3    Petterson, KJ4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.