Diagnostic accuracy of oropharyngeal cultures in infants and young children with cystic fibrosis

Pediatric Pulmonology

Volumn 28, Issue 5, 1999, Pages 321-328

  Rosenfeld, Margaret ^a,f   Emerson, Julia ^a   Accurso, Frank ^b   Armstrong, David ^c   Castile, Robert ^d   Grimwood, Keith ^c   Hiatt, Peter ^e   McCoy, Karen ^d   McNamara, Sharon ^a   Ramsey, Bonnie ^a   Wagener, Jeffrey ^b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c ROYAL CHILDREN'S HOSPITAL   (Australia)

^d OHIO STATE UNIVERSITY   (United States)

^e TEXAS CHILDREN S HOSPITAL   (United States)

^f SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

Author keywords

Bronchoalveolar lavage; Children; Colonization; Cystic fibrosis; Diagnostic accuracy; Haemophilus influenzae; Infants; Infection; Pseudomonas aeruginosa; Sensitivity; Specificity; Staphylococcus aureus

Indexed keywords

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL INFECTION; BACTERIUM CULTURE; CHILD; CHILDHOOD DISEASE; CYSTIC FIBROSIS; DIAGNOSTIC ACCURACY; FEMALE; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OROPHARYNX; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RESPIRATORY TRACT INFECTION; STAPHYLOCOCCUS AUREUS;

BACTERIAL INFECTIONS; BRONCHOALVEOLAR LAVAGE FLUID; BRONCHOSCOPY; CHILD, PRESCHOOL; CYSTIC FIBROSIS; FEMALE; HUMANS; INFANT; MALE; OROPHARYNX; PREDICTIVE VALUE OF TESTS; RESPIRATORY TRACT INFECTIONS; SENSITIVITY AND SPECIFICITY;

EID: 0032718969     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0496(199911)28:5<321::AID-PPUL3>3.0.CO;2-V     Document Type: Article

References (18)

1. Abman SH, Ogle JW, Harbeck RJ, Butler-Simon N, Hammond KB, Accurso FJ. Early bacteriologic, immunologic, and clinical courses of young infants with cystic fibrosis identified by neonatal screening. J Pediatr 1991;119:211-217.
2. Armstrong DS, Grimwood K, Carlin JB, Carzino R, Olinsky A, Phelan PD. Bronchoalveolar lavage or oropharyngeal cultures to identify lower respiratory pathogens in infants with cystic fibrosis. Pediatr Pulmonol 1996;21:267-275.
3. Balough K, McCubbin M, Weinberger M, Smits W, Ahrens R, Fick R. The relationship between infection and inflammation in the early stages of lung disease from cystic fibrosis. Pediatr Pulmonol 1995;20:63-70.
4. Khan TZ, Wagener JS, Bost T, Martinez J, Accurso FJ, Riches DWH. Early pulmonary inflammation in infants with cystic fibrosis. Am J Respir Crit Care Med 1995;151:1075-1082.
5. Iacocca VF, Sibinga M, Barbero G. Respiratory tract bacteriology in cystic fibrosis. Am J Dis Child 1963;106:115-24.
6. Huang NM, Van Loon EL, Shang KT. The flora of the respiratory tract of patients with cystic fibrosis of the pancreas. J Pediatr 1961;59:512-521.
7. Thomassen MJ, Klinger JD, Badger SJ, van Heeckeren DW, Stern RC. Cultures of thoracotomy specimens confirm usefulness of sputum cultures in cystic fibrosis. J Pediatr 1984;104:352-356.
8. Ramsey BW, Wentz KR, Smith AL, Richardson M, Williams-Warren J, Hedges DL, Gibson R, Redding GJ, Lent K, Harris K. Predictive value of oropharyngeal cultures for identifying lower airway bacteria in cystic fibrosis patients. Am Rev Respir Dis 1991;144:331-337.
9. Ramsey B, McNamara S, Gibson R, Emerson J, Rosenfeld M, Hiatt P, McConnell R, McCoy K, Lawrence C, Olson P. P. aeruginosa (Pa) colonization in young children with cystic fibrosis. Pediatr Pulmonol [Suppl] 1998;17:320-321.
10. Leisenring W, Sullivan Pepe M, Longton G. A marginal regression modeling framework for evaluating medical diagnostic tests. Stat Med 1997;16:1263-1281.
11. Kahn FW, Jones JM. Diagnosing bacterial respiratory infection by bronchoalveolar lavage. J Infect Dis 1987;155:862-869.
12. Thorpe JE, Baughman RP, Frame PT, Wessler TA, Staneck JL. Bronchoalveolar lavage for diagnosing acute bacterial pneumonia. J Infect Dis 1987;155:855-861.
13. Schmidt RM, Rosenkranz, HS. Antimicrobial activity of local anesthetics: lidocaine and procaine. J Infect Dis 1970;121:597-607.
14. Ravin CE, Latimer JM, Matsen JM. In vitro effects of lidocaine on anaerobic respiratory pathogens and strains of Haemophilus influenzae. Chest 1977;72:439-441.
15. Cystic Fibrosis Foundation Committee for Clinical Practice Guidelines. Clinical practice guidelines for cystic fibrosis. Bethesda, MD: Cystic Fibrosis Foundation; 1997. p 11.
16. Kerem E, Corey M, Gold R, Levison H. Pulmonary function and clinical course in patients with cystic fibrosis after pulmonary colonization with Pseudomonas aeruginosa. J Pediatr 1990;116: 714-719.
17. Abman SH, Ogle JW, Harback RJ, Butler-Simon N, Hammond KB, Accurso FJ. Early bacteriologic, immunologic, and clinical course of young infants with cystic fibrosis identified by neonatal screening. J Pediatr 1991;119:211-217.
18. Hudson VL, Wielinski CL, Regelmann WE. Prognostic implications of initial oropharyngeal bacteria flora in patients with cystic fibrosis diagnosed before the age of two years. J Pediatr 1993; 122:854-860.