Correlation of the intrinsic clearance of donepezil (Aricept®) between in vivo and in vitro studies in rat, dog and human

Xenobiotica

Volumn 29, Issue 11, 1999, Pages 1059-1072

  Matsui, K ^a   Taniguchi, S ^a   Yoshimura, T ^a  

^a EISAI CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; CHOLINESTERASE INHIBITOR; DONEPEZIL;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEALKYLATION; DEMETHYLATION; DOG; DRUG CLEARANCE; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY CLEARANCE; LIVER CLEARANCE; LIVER MICROSOME; MALE; NONHUMAN; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PLASMA CLEARANCE; RAT; SEX DIFFERENCE; SPECIES DIFFERENCE;

ANIMALIA; CANIS FAMILIARIS;

EID: 0032717488     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/004982599237958     Document Type: Article

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