Determination of the LOD and LOQ of an HPLC method using four different techniques

Pharmaceutical Technology

Volumn 23, Issue 10, 1999, Pages 86-90

  Paino, Thomas C ^a   Moore, Angola D ^a  

^a MALLINCKRODT PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONCENTRATION RESPONSE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; REVIEW; SIGNAL NOISE RATIO;

EID: 0032717452     PISSN: 01478087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (10)

1. USP 23 (1225) (United States Pharmacopeial Convention, Inc., Rockville, MD, 1995), p. 1983.
2. M.E. Swartz and I.S. Krull, "Validation of Chromatographic Methods," Pharm. Technol. 22 (3), 104-118 (1998).
3. M.E. Swartz and I.S. Krull, "Frequently Asked Questions about Analytical Method Validation," LC·GC 16 (5), 464-476 (1998).
4. M.E. Swartz and I.S. Krull, "Determining Limits of Detection and Quantitation," LC·GC 16 (10), 922-924 (1998).
5. American Chemical Society Committee Report, "Guidelines for Data Acquisition and Data Quality Evaluation in Environmental Chemistry," Anal. Chem. 52, 2242 (1980).
6. American Chemical Society Committee Report, "Principles of Environmental Measurement," Anal. Chem. 55, 2210-2218 (1983).
7. J.K. Taylor, Quality Assurance of Chemical Measurements (Lewis Publishers, Inc., Chelsea, Michigan, 1987), pp. 79-82.
8. J.A. Glaser et al., "Trace Analysis for Waste Waters - Method Detection Limit," Environ. Sci. Technol. 15, 1426-1435 (1981).
9. ICH Q2B, "Validation of Analytical Procedures: Methodology" (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use, Geneva, Switzerland, November 1996).
10. A. Hubaux and G. Vos, "Decision and Detection Limits for Linear Calibration Curves," Anal. Chem. 42 (8), 849-855 (1970).