Detection and characterization of HLA class I molecules in the supernatant of an hepatocarcinoma cell line and of EBV- transformed B cell lines

Human Immunology

Volumn 60, Issue 5, 1999, Pages 435-441

  Datema, Gert ^a   Mulder, Arend ^a,b   Claas, Frans H J ^a   Van Den Elsen, Peter J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SVM Found Adv Pub Hlth E   (Netherlands)

Author keywords

Class I heavy chain; HLA complexes; Molecular weight; Monoclonal antibody; Soluble HLA

Indexed keywords

HLA ANTIGEN CLASS 1; MONOCLONAL ANTIBODY;

ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; EPSTEIN BARR VIRUS; HLA SYSTEM; HUMAN; LIVER CELL CARCINOMA; LIVER TRANSPLANTATION; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; PRIORITY JOURNAL; SUPERNATANT;

BLOTTING, WESTERN; CULTURE MEDIA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; INTERFERON TYPE II; MOLECULAR WEIGHT; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 0032717437     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00013-0     Document Type: Article

References (31)

1. Davies HffS, Pollard SG, Calne RY: Soluble HLA antigens in the circulation of liver graft recipients. Transplantation 47:524, 1989.
2. Zavazava N, Bottcher H, Muller Ruchholtz W: Soluble MHC class I antigens (sHLA) and anti-HLA antibodies in heart and kidney allograft recipients. Tissue Antigens 42:20, 1993.
3. Chauhan B, Mathew JM, Shenoy S, Flye MW, Howard T, Mohanakumar T: Donor human leukocyte antigens in the circulation of liver allograft recipients. Clin Transplantation 9:14, 1995.
4. 2-microglobulin-free class I heavy chains are released from the surface of activated and leukemia cells by a metalloprotease. J Biol Chem 269:6689, 1994.
5. De Vito-Haynes LD, Demaria S, Bushkin Y, Burlingham WJ: The metalloprotease-mediated pathway is essential for generation of soluble HLA class I proteins by activated cells in vitro: proposed mechanism for soluble HLA release in transplant rejection. Hum Immunol 59:426, 1998.
6. Puppo F, Scudeletti M, Indiveri F, Ferrone S: Serum HLA class I antigens: markers and modulators of an immune response? Immunol Today 16:124, 1995.
7. Francavilla R, Hadzic N, Underhill J, Heaton N, Rela M, Mieli-Vergani G, Donaldson P: Role of HLA compatibility in pediatric liver transplantation. Transplantation 66: 53, 1998.
8. Poli F, Scalamogna M, Aniasi A, Brambilla C, Cardillo M, Crespiatico L, Diomelli B, Pedranzini L, Sirchia G: A retrospective evaluation of HLA-A, B and -DRB1 matching in liver transplantation. Transpl Int 11(Suppl 1):S347, 1998.
9. Kamada N, Wight DGD: Antigen-specific immunosuppression induced by liver transpantation in the rat. Transplantation 38:217, 1983.
10. Mathew JM, Marsh JW, Susskind B, Mohanakumar T: Analysis of T cell responses in liver allograft recipients. Evidence for deletion of donor-specific cytotoxic T-cells in the peripheral circulation. J Clin Invest 91:900, 1993.
11. a rat class I major histocompatibility antigens induce specific alloimmunity. Transplantation 60:602, 1995.
12. Zavazava N, Hausmann R, Muller-Ruchholtz W: Inhibition of anti-HLA-B7 alloreactive CTL by affinity-purified soluble HLA. Transplantation 51:838, 1991.
13. Hausmann R, Zavazava N, Steinmann J, Muller-Ruchholtz W. Interaction of papain-digested HLA class I molecules with human alloreactive cytotoxic T lymphocytes (CTL). Clin Exp Immunol 91:183, 1992.
14. Porto JD, Johansen TE, Catipovic B, Parfiit DJ, Tuveson D, Gether U, Kozlowski S, Fearon DT, Schneck JP: A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations. Proc Natl Acad Sci USA 90:6671, 1993.
15. Mathew JM, Shenoy S, Phelan D, Lowell J, Howard T, Mohanakumar T: Biochemical and immunological evaluation of donor-specific soluble HLA in the circulation of liver transplant patients. Transplantation 62:217, 1996.
16. Zavazava N, Kronke M: Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes. Nature Med 9:1005, 1996.
17. Knowles BB, Howe CC, Aden DP: Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209:497, 1980.
18. Tanabe M, Sekimata M, Ferrone S, Takiguchi M: Structural and functional analysis of monomorphic determinants recognized by monoclonal antibodies reacting with the HLA class I α3 domain. J Immunol 148:3202, 1992.
19. Burlingham WJ, Jankowska-Gan E, DeVito-Haynes L, Fechner JH, Hogan KT, Claas FHJ, Mulder A, Wang X, Ferrone S: HLA-A*0201 antigen mimicry by anti-idiotypic antibodies. J Immunol 161:6705, 1998.
20. Koelman CA, Mulder A, Jutte NHPM, Vaessen LMB, Balk AHMM, Weimar W, Doxiadis UN, Claas FHJ: The application of human monoclonal antibodies for monitoring donor derived soluble HLA class I molecules in the serum of heart transplant patients. Hum Immunol 59: 106, 1998.
21. Brouwenstijn N, Gaugler B, Kruse KM, van der Spek CW, Mulder A, Osanto S, van den Eynde BJ, Schrier PI: Renal-cell carcinoma-specific lysis by cytotoxic T-lymphocyte clones isolated from peripheral blood lymphocytes and tumor-infiltrating lymphocytes. Int J Cancer 68:177, 1996.
22. Neefjes JJ, Stollorz V, Peters PJ, Geuze HJ, Ploegh HL: The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell 61:171, 1990.
23. Stam NJ, Vroom ThM, Peters PJ, Pastoors EB, Ploegh HL: HLA-A- and HLA-B- specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy. Int Immunol 2:113, 1990.
24. 2-microglobulin from HLA class I heavy chains correlates with acquisition of epitopes in the cytoplasmic tail. J Immunol 154:5205, 1995.
25. Doxiadis I, Westhoff U, Grosse-Wilde H: Quantification of soluble HLA class I gene products by an enzyme linked immunosorbent assay. Blut 59:449, 1989.
26. Neefjes JJ, Breur-Vriesendorp BS, van Seventer GA, Ivanyi P, Ploegh HL: An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes. Hum Immunol 16:169, 1986.
27. Dobbe LME, Stam NJ, Neefjes JJ, Giphart MJ: Biochemical complexity of serum HLA class I molecules. Immunogenetics 27:203, 1988.
28. Geissler EK, Korzun WJ, Graeb C: Secreted donor-MHC class I antigen prolongs liver allograft survival and inhibits recipient anti-donor cytotoxic T lymphocyte responses. Transplantation 64:782, 1997.
29. Kurokohchi K, Carrington M, Mann DL, Simonis TB, Alexander-Miller MA, Feinstone SM, Akatsuka T, Berzofsky JA: Expression of HLA class I molecules and the transporter associated with antigen processing in hepatocellular carcinoma. Hepatology 23:1181, 1996.
30. Krangel MS: Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. J Exp Med 163:1173, 1986.
31. Suciu-Foca N, Reed E, D'Agati VD, Ho E, Cohen DJ, Benvenisty AI, McCabe R, Brensilver JM, King DW, Hardy MA: Soluble HLA antigens, anti-HLA antibodies, and antiidiotypic antibodies in the circulation of renal transplant recipients. Transplantation 51:593, 1991.