Mutant channels contribute < 50% to Na+ current in paramyotonia congenita muscle

Brain

Volumn 122, Issue 6, 1999, Pages 1085-1092

  Mitrovic, Nenad ^b   George Jr , Alfred L ^a   Rüdel, Reinhardt ^c   Lehmann Horn, Frank ^c   Lerche, Holger ^c  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF ULM   (Germany)

^c NONE

Author keywords

Channelopathies; Human skeletal muscle; Inactivation; Na+ channel; Patch clamp

Indexed keywords

MUTANT PROTEIN; SODIUM CHANNEL; VOLTAGE GATED CHANNEL FORMING PROTEIN;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; DISEASE SEVERITY; DNA TRANSFECTION; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; KIDNEY CELL; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; SODIUM CURRENT; THOMSEN DISEASE;

AMINO ACID SUBSTITUTION; CELL LINE; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; MYOTONIA CONGENITA; POINT MUTATION; RECOMBINANT PROTEINS; SODIUM CHANNELS; THERMODYNAMICS; TRANSFECTION;

EID: 0032717312     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/122.6.1085     Document Type: Article

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