1-Imidazolylcarbonyloxy-substituted tetrahydroquinolines and pyridines: Synthesis and evaluation of P450 TxA2 inhibition

Archiv der Pharmazie

Volumn 332, Issue 10, 1999, Pages 358-362

  Hartmann, Rolf W ^a   Frotscher, Martin ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

1 imidazolylcarbonyloxy substituted tetrahydroquinolines and pyridines; Pharmacophore model; Prophylaxis of metastases; Thromboxane A2 synthase (P450 TxA2) inhibitors

Indexed keywords

5 (1 IMIDAZOLYLCARBONYLOXY) 5,6,7,8 TETRAHYDROQUINOLINE; CYTOCHROME P450; DAZOXIBEN; PYRIDINE DERIVATIVE; QUINOLINE DERIVATIVE; THROMBOXANE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; METASTASIS; PHARMACOPHORE; PRIORITY JOURNAL;

HUMANS; PYRIDINES; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBOXANE-A SYNTHASE;

EID: 0032716613     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(199910)332:10<358::AID-ARDP358>3.0.CO;2-D     Document Type: Article

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