Lung cancer risk in families of nonsmoking probands: Heterogeneity by age at diagnosis

Genetic Epidemiology

Volumn 17, Issue 4, 1999, Pages 253-273

  Yang, Ping ^a   Schwartz, A G ^b   McAllister, A E ^c   Swanson, G M ^d   Aston, C E ^c  

^a MAYO CLINIC   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Chronic lung diseases; Familial aggregation; Lung cancer; Mendelian inheritance; Tobacco exposure

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CANCER RISK; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; GENETIC LINKAGE; GENETIC RISK; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; RISK FACTOR; SMOKING;

ADULT; AGE DISTRIBUTION; AGED; CHROMOSOME SEGREGATION; FEMALE; GENETIC HETEROGENEITY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; MODELS, GENETIC; PEDIGREE; POPULATION SURVEILLANCE; REGRESSION ANALYSIS; RISK FACTORS; SMOKING;

NICOTIANA TABACUM;

EID: 0032713814     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(199911)17:4<253::AID-GEPI2>3.0.CO;2-K     Document Type: Article

References (59)

1. Akaike H. 1974. A new look at the statistical model identification. IEEE Trans Automatic Control AC 19:716-723.
2. Amos CI, Caporaso NE, Weston A. 1992. Host factors in lung cancer risk: a review of interdisciplinary studies. Cancer Epidemiol Biomarkers Prev 1:505-513.
3. Anttila S, Luostarinen L, Hirvonen A, Elovaara E, Karjalainen A, Nurminen T, Hayes JD, Vainio H, Ketterer D 1995. Pulmonary expression of glutathione S-transferase M3 in lung cancer patients: Association with GSTM1 polymorphism, smoking, and asbestos exposure. Cancer Res 55:3305-3309.
4. Bateson W. 1907. The progress of genetics since the rediscovery of Mendel's paper. Progressus Rei Botanicae 1:368.
5. Beaty TH. 1997. Evolving methods in genetic epidemiology. I. Analysis of genetic and environmental factors in family studies. Epidemiol Rev 19:14-23.
6. Bonney GE. 1986. Regressive logistics models for familial diseases and other binary traits. Biometrics 42:611-625.
7. Cannings C, Thompson EA. 1977. Ascertainment in the sequential sampling of pedigrees. Clin Genet 12:208-212.
8. Chern HD, Lesnick T, Becich MJ, Dickinson A, Persad R, Sibley G, Smith P, Romkes-Sparks M, Branch RA. 1994. Association of low CYP3A4 activity and p53 mutation in aggressive bladder cancer in man. Can J Physiol Pharmacol 7281:603.
9. Chern HD, Persad RA, Fleming CM, Bryant JL, Romkes-Sparks M, Sibley GA, Smith PJB, Branch RA. 1995. N-acetyltransferase slow acetylator phenotype increases susceptibility to occupational related aggressive bladder cancer. AACR Conference Proc 36:121.
10. Cohen BH. 1980. Chronic obstructive pulmonary disease: A challenge in genetic epidemiology. Am J Epidemiol 112:274-288.
11. Cohen BH, Graves CG, Levy DA, Permutt S, Diamond EL, Kreiss P, Menkes HA, Quaskey S, Tockman MS. 1977. A common familial component in lung cancer and chronic obstructive pulmonary disease. Lancet 2:523-526.
12. 1-antitrypsin deficiency. In: Scriver CR, Beaudet AL, Sly WS, Valle D, editors. The metabolic and molecular bases of inherited disease, 7th ed. New York: The McGraw-Hill Company, p 4125-4158.
13. Elston RC, George VT. 1989. Age of onset, age at examination, and other covariates in the analysis of family data. Genet Epidemiol 6:217-220.
14. Gaedigk A, Blum M, Gaedigk R, Eichelbaum M, Meyer UA. 1991. Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphisms. Am J Hum Genet 48:943-950.
15. Gauderman WJ, Morrison JL, Carpenter CL, Thomas DC. 1997. Analysis of gene-smoking interaction in lung cancer. Genet Epidemiol 14:199-214.
16. Illis WR, Swanson GM, Satariano ER, Schwartz AG. 1987. Summary measures of occupational history: A comparison of latest occupation and industry with usual occupation and industry. Am J Public Health 77:1532-1534.
17. Jacqz E, Hall S, Branch RA. 1986. Genetically determined polymorphisms in oxidate drug metabolism. Hepatology 6:1020-1032.
18. Khoury MJ, Beaty TH, Cohen BH. 1993. Genetic approaches to familial aggregation. I. Analysis of heritability. In: Khoury MJ, Beaty TH, Cohen BH, editors. Fundamentals of genetic epidemiology. New York: Oxford University Press, p 200-232.
19. Lalouel JM, Morton NE. 1981. Complex segregation analysis with pointers. Hum Hered 31:312-321.
20. Levois M, Switzer P. 1998. Differential exposure misclassification in case-control studies of environmental tobacco smoke and lung cancer. J Clin Epidemiol 51:37-54.
21. Lower GM. 1982. Concepts in causality: Chemically induced human bladder cancer. Cancer 49:1056-1066.
22. Lustbader ED, Williams WR, Bondy ML, Strom S, Strong LC. 1992. Segregation analysis of cancer in families of childhood soft-tissue-sarcoma patients. Am J Hum Genet 51:344-356.
23. Lynch HT, Kimberling WJ, Markvicka SE, Biscone KA, Lynch JF, Whorton E, Mailliard J. 1986. Genetics and smoking-associated cancers. Cancer 57:1640-1646.
24. Mack W, Langholz B, Thomas DC. 1990. Survival models for familial aggregation of cancer. Environ Health Perspect 37:27-35.
25. McDuffie HH. 1991. Clustering of cancer in families of patients with primary lung cancer. J Clin Epidemiol 44:69-76.
26. Miller JA, Miller EC. 1983. Some historical aspects of N-aryl carcinogens and their metabolic activation. Environ Health Perspect 49:3-12.
27. Mizzo M, Sozzi G, Musso K, Pilotti S, Incarbone M, Pastorino U, Peirotti MA. 1996. Microsatellite alterations in bronchial and sputum specimens of lung cancer patients. Cancer Res 56:2285-2288.
28. Nakachi K, Imai K, Hayashi S-i, Watanabe J, Kawajiri K. 1991. Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. Cancer Res 5119.5177-5180.
29. National Cancer Institute Division of Cancer Prevention and Control. 1988. Annual Cancer Statistics Review. Bethesda: National Institutes of Health.
30. Nebert DW, Nelson DR, Coon MJ, Estabrook RW, Feyereisen R, Fujii-Kuriyama Y, Gonzalez FJ, Guengerich FP, Gunsalus IC, Johnson EF, Loper JC, Sato R, Waterman MR, Waxman DJ. 1991. The P450 superfamily: Update on new sequence, gene mapping, and recommended nomenclature. DNA Cell Biol 10:1-14.
31. Ooi WL, Elston RC, Chen VW, Bailey-Wilson JE, Rothschild H. 1986. Increased familial risk for lung cancer. J Natl Cancer Inst 76:217-222.
32. Osann KE. 1991. Lung cancer in women: The importance of smoking, family history of cancer, and medical history of respiratory disease. Cancer Res 51:4893-4897.
33. Ries LAG, Miller BA, Hankey BF, Kosary CL, Harras A, Edwards BK, editors. 1994. SEER Cancer Statistics Review, 1973-1991: Tables and Graphs, National Cancer Institute. NIH Pub. No. 94-2789, Bethesda, MD: National Institutes of Health.
34. Romkes-Sparks M, Mnuskin A, Chern H-D, Persad R, Branch RA. 1993. Cytochrome P4502D6 mRNA expression in bladder tissue is related to debrisoquine hydroxylation activity in normal subjects and patients with bladder cancer. AACR Conference Proc 34:143.
35. Samet JM, Humble CG, Pathak DR. 1986. Personal and family history of respiratory disease and lung cancer risk. Am Rev Respir Dis 134:466-470.
36. SAS Institute Inc. 1990. SAS Technical Report P-200, SAS/STAT Software: CALIS and LOGISTIC Procedures, Release 6.04, Cary, NC: SAS Institute Inc.
37. Schlesselman JJ. 1982. Multivariate analysis. In: Schlesselman JJ, editor. Case-control studies: design, conduct, analysis. New York: Oxford University Press, p 227-290.
38. Schottenfeld D. 1996. Epidemiology of lung cancer. In: Pass HI, Mitchell JB, Johnson DH, Turrisi AT, editors. Lung cancer principles and practice. Philadelphia: Lippincott-Raven Publishers, p 305-321.
39. Schwartz AG, Yang P, Swanson GM. 1996. Familial risk of lung cancer among nonsmokers and their relatives. Am J Epidemiol 144:554-562.
40. Schwartz AG, Rothrock M, Yang P, Swanson GM. 1999. Increased cancer risk among relatives of nonsmoking lung cancer cases. Genet Epidemiol (in press).
41. Seidegård J, Pero RW, Miller DG, Beattie EJ. 1986. A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer. Carcinogenesis 7:751-753.
42. Sellers TA. 1996. Familial predisposition to lung cancer. In: Eeles RA, Ponder BAJ, Easton DF, Horwich A, editors. Genetic predisposition to cancer. London: Chapman & Hall, p 344-353.
43. Sellers TA, Ooi WL, Elston RC, Chen VW, Bailey-Wilson JE, Rothschild H. 1987. Increased familial risk for non-lung cancer among relatives of lung cancer patients. Am J Epidemiol 126:237-246.
44. Sellers TA, Bailey-Wilson JE, Elston RC, Wilson AF, Elston GZ, Ooi WL, Rothschild H. 1990. Evidence for Mendelian inheritance in the pathogenesis of lung cancer. J Natl Cancer Inst 82:1272-1279.
45. Sellers TA, Potter JD, Folsom AR. 1991. Association of incident lung cancer with family history of female reproductive cancers: The Iowa Women's Health Study. Genet Epidemiol 8:199-208.
46. Sellers TA, Potter JD, Bailey-Wilson JE, Rich SS, Rothschild H, Elston RC. 1992. Lung cancer detection and prevention: Evidence for an interaction between smoking and genetic predisposition. Cancer Res 52(Suppl):2694s-2697s.
47. Shaw GL, Falk RT, Pickle LW, Mason TJ, Buffler PA. 1991. Lung cancer risk associated with cancer in relatives. J Clin Epidemiol 44:429-437.
48. Shopland DR. 1996. Cigarette smoking as a cause of cancer. In Cancer Rates and Risks. National Cancer Institute, NIH Publication No. 967-691. 4th edition. Bethesda: National Institutes of Health, p 67-72.
49. Statistical Analysis for Genetic Epidemiology (SAGE) Version 2 1991. Shreveport: Department of Biometry and Genetics, Louisiana State University Medical Center.
50. Swanson GM, Schwartz AG, Brown KL. 1985. Population-based occupational cancer incidence surveillance. J Occup Med 27:439-444.
51. Tokuhata GK, Lilienfeld AM. 1963. Familial aggregation of lung cancer in humans. J Natl Cancer Inst 30:289-312.
52. U.S.Bureau of the Census 1981. Alphabetic Index of Industries and Occupations, 1980. Washington, DC: Government Printing Office.
53. Weiland I, Ammermuller T, Bohm M, Totzeck B, Rajewsky MF. 1996. Microsatellite instability and loss of heterozygosity at the hMLH1 locus on chromosome 3p21 occur in a subset of nonsmall cell lung carcinomas. Oncol Res 8:1-5.
54. Williams WR, Anderson DE. 1984. Genetic epidemiology of breast cancer; segregation analysis of 200 Danish pedigrees. Genet Epidemiol 1:7-20.
55. Wu AH, Yu MC, Thomas DC, Pike MC, Henderson BE. 1988. Personal and family history of lung disease as risk factors for adenocarcinoma of the lung. Cancer Res 48:7279-7284.
56. Yang P, Buetow KH, Lustbader E, Lanier AP, McMahon BJ, McGlynn KA. 1990. Evidence for a major locus modifying risk of hepatocellular carcinoma. Am J Hum Genet 47(Suppl):A25.
57. Yang P, Romkes M, Schwartz AG, Rittmeyer L, Adedoyin A, Landreneau R, Mauro K, Branch RA. 1996. Polymorphisms at the NAT2* locus associated with increased cancer risk in first-degree relatives of lung cancer patients. Genet Epidemiol 3:308-309.
58. Yang P, Schwartz AG, McAllister AE, Aston CE, Swanson GM. 1997a. Genetic analysis of families with nonsmoking lung cancer probands. Genet Epidemiol 14:181-197.
59. 1AT) deficiency carriers found in lung cancer patients. Am J Hum Genet 61:.A15.