Target and filter concepts for accelerator-driven boron neutron capture therapy applications

Nuclear Technology

Volumn 125, Issue 1, 1999, Pages 104-114

  Powell, James R ^a   Ludewig, Hans ^a   Todosow, Michael ^a   Reich, Morris ^a  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Boron capture therapy; Neutron source; Target filter

Indexed keywords

BERYLLIUM; IRON; LITHIUM; MAGNESIUM; METAL FOIL; METALLIC FILMS; NEUTRON SCATTERING; PARTICLE BEAMS; PROTONS; RADIOTHERAPY; TARGETS; TISSUE;

BORON NEUTRON CAPTURE THERAPY (BNCT);

NEUTRON SOURCES;

EID: 0032712964     PISSN: 00295450     EISSN: None     Source Type: Journal    
DOI: 10.13182/nt99-a2936     Document Type: Article

References (16)

1. P. A. ZAHL and F. S. COOPER, "Physical and Biological Considerations in the Use of Slow Neutrons for Cancer Therapy," Radio!., 37, 673 (1941).
2. W. H. SWEET, "The Uses of Nuclear Disintegration in the Diagnosis and Treatment of Brain Tumor," N. Eng. J. Med., 245, 875 (1951).
3. D. N. SLATKIN, "A History of Boron Neutron Capture Therapy of Brain Tumors," Brain, 114, 1609 (1991).
4. R. G. FAIRCHILD, "Development and Dosimetry of an Epithermal Neutron Beam for Possible Use in Neutron Capture Therapy," Phys. Med. Biol., 10, 4, 491 (1965).
5. R. G. FAIRCHILD et al., "Installation and Testing of an Optimized Epithermal Neutron Beam at the Brookhaven Medical Research Reactor (BMRR)," Neutron Beam Design, Development and Performance for Neutron Capture Therapy, p. 185, O. HARLING, J. BERNARD, and R. ZAMENHOF, Eds., Plenum Press, New York (1989).
6. H. B. LIU and R. M. BRUGGER, "An Epithermal Neutron Beam from the MURR and from an Accelerator Source Compared to the Beam at the BMRR," Advances in Neutron Capture Therapy, p. 109, A. H. SOLWAY, Ed., Plenum Press, New York (1993).
7. O. K. HARLING, J. A. BERNARD, and R. G. ZAMENHOF, Neutron Beam Design, Development and Performance for Neutron Capture Therapy, Plenum Press, New York (1989).
8. Proc. 1st Int. Workshop Accelerator Based Neutron Sources for Boron Neutron Capture Therapy, Jackson, Wyoming, September 11-14, 1994, D. W. NIGG, Ed.
9. C. K. C. WANG, P. E. EGGERS, and H. L. CRAWFORD, "Accelerator Neutron Irradiation Facility for Hospital Based Neutron Capture Therapy," Advances in Neutron Capture Therapy, p. 119, A. H. SOLWAY, Ed., Plenum Press, New York (1993).
10. T. H. WU, R. BRUGGER, and J. F. KUNZE, "Low Energy Accelerator-Based Neutron Sources for Neutron Capture Therapy," Advances in Neutron Capture Therapy, p. 105, A. H. SOLWAY, Ed., Plenum Press, New York (1993).
11. D. I. GARBER and R. R. KINSEY, "Neutron Cross Sections, Vol. II, Curves," 3rd ed., BNL 325, Brookhaven National Laboratory (1976).
12. Handbook of Chemistry and Physics, 67th ed., R. C. WEAST, Ed., Chemical Rubber Company (1987).
13. "MCNP: A General Monte Carlo Code for Neutron and Photon Transport," Version 3A, LA-7396-MS, J. F. BRIESMEISTER, Ed., Los Alamos National Laboratory (1986).
14. P. THIEBERG, Brookhaven National Laboratory, Personal Communication (1995).
15. J. POWELL, H. LUDEWIG, M. TODOSOW, and M. REICH, "NIFTI and DISCOS: New Concepts for a Compact Accelerator Neutron Source for Boron Neutron Capture Therapy Applications," BNL 60635, Brookhaven National Laboratory (1995).
16. S. D. CLEMENT et al., "Monte Carlo Methods of Neutron Capture Therapy at the MIT Research Reactor (MITR-I)," Neutron Beam Design, Development, and Performance For Neutron Capture Therapy, p. 51, O. HARDING, J. BERNARD, and R. ZAMENHOF, Eds., Plenum Press, New York (1989).