The aspartate aminotransferase-catalysed exchange of the α-protons of aspartate and glutamate: The effects of the R386A and R292V mutations on this exchange reaction

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1434, Issue 1, 1999, Pages 191-201

  Mahon, Marrita M ^a   Graber, Rachel ^b   Christen, Philipp ^b   Malthouse, J Paul G ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Proton exchange; Amino acid; Aspartate aminotransferase

Indexed keywords

ASPARTATE AMINOTRANSFERASE; ASPARTIC ACID; GLUTAMIC ACID;

ARTICLE; CATALYSIS; ENZYME ANALYSIS; ESCHERICHIA COLI; MATHEMATICAL ANALYSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; REACTION ANALYSIS; STEREOSPECIFICITY;

ASPARTATE AMINOTRANSFERASES; ASPARTIC ACID; DEUTERIUM; GLUTAMIC ACID; GLYCINE HYDROXYMETHYLTRANSFERASE; HYDROGEN-ION CONCENTRATION; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MUTATION; PROTONS; STEREOISOMERISM; TRYPTOPHAN SYNTHASE;

ESCHERICHIA COLI;

EID: 0032712167     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(99)00181-8     Document Type: Article

References (38)

1. John R.A. Biochim. Biophys. Acta. 1248:1995;81-96.
2. Hayashi H. J. Biochem. 118:1995;463-473.
3. L. Davis, D.E. Metzler, Enzymes, 3rd Edn. Vol. 3, 1972, pp. 33-74.
4. Dunathan H.C. Proc. Natl. Acad. Sci. USA. 55:1966;712-716.
5. Dunathan H.C. Adv. Enzymol. Relat. Areas Mol. Biol. 38:1971;79-134.
6. Dunathan H.C., Voet J.G. Proc. Natl. Acad. Sci. USA. 71:1974;3888-3891.
7. Malthouse J.P.G., Milne J.J., Gariani L.S. Biochem. J. 274:1991;807-812.
8. Milne J.J., Malthouse J.P.G. Biochem. Soc. Trans. 22:1994;43S.
9. Milne J.J., Malthouse J.P.G. Biochem. J. 311:1995;1015-1019.
10. Milne J.J., Malthouse J.P.G. Biochem. J. 314:1996;787-791.
11. Fitzpatrick T.B., Malthouse J.P.G. Biochem. Soc. Trans. 24:1996;132S.
12. Fitzpatrick T.B., Malthouse J.P.G. Eur. J. Biochem. 252:1998;113-117.
13. Mahon M.M., Gramatikova S.I., Christen P., Fitzpatrick T.B., Malthouse J.P.G. FEBS Lett. 427:1998;74-78.
14. Fitzpatrick T.B., Malthouse J.P.G. Biochim. Biophys. Acta. 1386:1998;220-226.
15. Cooper A.J.L. J. Biol. Chem. 251:1976;1088-1096.
16. Babu U.M., Johnston R.B. Biochemistry. 15:1976;5671-5678.
17. Walter U., Luthe H., Gerhadt F., Soling H.D. Eur. J. Biochem. 59:1975;395-403.
18. Gehring H. Biochemistry. 23:1984;6335-6340.
19. Kirsch J.F., Eichele G., Ford G.C., Vincent M.G., Jansonius J.J., Gehring H., Christen P. J. Mol. Biol. 174:1984;497-525.
20. Graber R., Kasper P., Malashkevich V.N., Sandmeier E., Berger P., Gehring H., Jansonius J.N., Christen P. Eur. J. Biochem. 232:1995;686-690.
21. Birchmeier W., Wilson K.J., Christen P. J. Biol. Chem. 248:1973;1751-1759.
22. Ziak M., Jager J., Malashkevich V.N., Gehring H., Jaussi R., Jansonius J.N., Christen P. Eur. J. Biochem. 211:1993;475-484.
23. Kamitori S., Okamoto A., Hirotsu K., Higuchi T., Kuramitsu S., Kagamiyama H., Matsuura Y., Katsube Y. J. Biochem. 108:1990;175-184.
24. A. Cornish-Bowden, in: Fundamentals of Enzyme Kinetics, Portland Press, London, 1995, pp. 87-88.
25. Malthouse J.P.G., Milne J.J., Fitzpatrick T.B., Mahon M.M. Biochem. Soc. Trans. 24:1996;134S.
26. Malthouse J.P.G., Fitzpatrick T.B., Mahon M.M. Biochem. Soc. Trans. 26:1998;66.
27. Inoue Y., Kuramitsu S., Inoue K., Kagamiyama H., Hiromi K., Tanase S., Morino Y. J. Biol. Chem. 264:1989;9673-9681.
28. Kochhar S., Christen P. Eur. J. Biochem. 175:1988;433-438.
29. Hayashi H., Kuramitsu S., Inoue Y., Morino Y., Kagamiyama H. Biochem. Biophys. Res. Commun. 159:1989;337-342.
30. Velick S.F., Vavra J. J. Biol. Chem. 237:1962;2109-2122.
31. Danishefsky A.T., Onnufer J.J., Petsko G.A., Ringe D. Biochemistry. 30:1991;1980-1985.
32. Sandmeier E., Christen P. J. Biol. Chem. 257:1982;6745-6750.
33. Cronin C.N., Kirsch J.F. Biochemistry. 27:1988;4572-4579.
34. Kamitori S., Okamoto A., Hirotsu K., Higuchi T., Kuramitsu S., Kagamiyama H., Matsuura Y., Katsube Y. J. Biochem. 108:1990;175-184.
35. A. Arnone, P.D. Briley, P.H. Rogers, C.C. Hyde, C.M. Metzler, D.E. Metzler, in: J.F. Griffin, W.L. Duax (Eds.), Molecular Structure and Biological Activity, Elsevier Science, New York, 1982, pp. 57-77.
36. Rhee S., Silva M.M., Hyde C.C., Rogers P.H., Metzler C.M., Metzler D.E., Arnone A. J. Biol. Chem. 272:1997;17293-17302.
37. Kochhar S., Christen P. Eur. J. Biochem. 203:1992;563-569.
38. 6, Vol. 2, Birkhauser Verlag, Basel, 1987, pp. 89-102.