Elastase substrate specificity tailored through substrate-assisted catalysis and phage display

Protein Engineering

Volumn 12, Issue 11, 1999, Pages 981-987

  Dall'Acqua, William ^a   Halin, Cornelia ^a,b   Rodrigues, Maria L ^a   Carter, Paul ^a  

^a GENENTECH INC   (United States)

^b ETH ZURICH   (Switzerland)

Author keywords

Human neutrophil elastase; Phage display; Protease specificity; Substrate assisted catalysis

Indexed keywords

ALANINE; ARGININE; HISTIDINE; LEUKOCYTE ELASTASE; METHIONINE; THREONINE; VALINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; EMBRYO; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; PHAGE DISPLAY; PICHIA PASTORIS; PRIORITY JOURNAL; PROTEIN DEGRADATION;

FELIS CATUS; PICHIA PASTORIS;

EID: 0032711849     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/12.11.981     Document Type: Article

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