Fluoxetine versus amitriptyline in the treatment of major depression with associated anxiety (anxious depression): A double-blind comparison

International Clinical Psychopharmacology

Volumn 14, Issue 6, 1999, Pages 321-327

  Versiani, M ^c   Ontiveros, A ^c   Mazzotti, G ^c   Ospina, J ^c   Davila J ^c   Mata, S ^c   Pacheco, A ^c   Plewes, J ^a   Tamura, R ^a   Palacios, M ^b  

^a ELI LILLY AND COMPANY   (United States)

^b Eli Lilly Campania de Venezuela SA   (United States)

^c NONE

Author keywords

Amitriptyline; Anxiety; Anxious depression; Fluoxetine; Major depression

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; FLUOXETINE;

ABDOMINAL PAIN; ADULT; AMBLYOPIA; ANXIETY; ANXIETY NEUROSIS; ARTICLE; ASTHENIA; CLINICAL TRIAL; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; DYSPEPSIA; FEMALE; GASTRITIS; HAMILTON SCALE; HEADACHE; HUMAN; INSOMNIA; LIBIDO; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SOMNOLENCE; SWEATING; TACHYCARDIA; TREMOR; VERTIGO; WEIGHT GAIN; XEROSTOMIA;

EID: 0032711240     PISSN: 02681315     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004850-199911000-00001     Document Type: Article

References (37)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th Edn. Washington, DC: American Psychiatric Association.
2. Akiskal HS (1990). Toward a clinical understanding of the relationship of anxiety and depressive disorders. In: Comorbidity of Mood and Anxiety Disorders (Maser JD, Cloninger CR, ed.), Washington, DC: American Psychiatric Press. pp. 597-607.
3. Akiskal HS (1992) Le deprime avant la depression. Encephale 18:485-489.
4. Akiskal HS, Lemmi H, Dickson H, King D, Yerevanian B, Valkenburg CV (1984) Chronic depressions. Part 2. Sleep EEG differentiation of primary dysthymic disorders from anxious depressions. J Affect Disord 6:287-295.
5. Angst J, Vollrath M, Merikangas KR, Ernst C (1990) Comorbidity of anxiety and depression in the Zurich cohort study of young adults. In: Comorbidity of Mood and Anxiety Disorders (Maser JD, Cloninger CR, ed.), Washington, DC: American Psychiatric Press. pp. 123-137.
6. Bressa GM, Grugnoli R, Pancheri P (1989) A controlled comparison of fluoxetine and amitriptyline in major depression. Clin Psychopharmacol 4:69-73.
7. Chouinard G (1985) A double-blind controlled clinical trial of fluoxetine and amitriptyline in patients with major depressive disorder. J Clin Psychiatry 46:32-37.
8. Clayton PJ, Grove WM, Coryell W, Keller M, Hirschfeld R, Fawcett J (1991) Follow-up and family study of anxious depression. Am J Psychiatry 148:1512-1517.
9. Cleary MA, Guy W (1975) Factor analysis of the Hamilton depression scale. Drugs Experimental Clinical Research 1:115-120.
10. Cloninger CR, Martin RL, Guze SB, Clayton PL (1990) The empirical structure of psychiatric comorbidity and its theoretical significance. In: Comorbidity of Mood and Anxiety Disorders (Maser JD, Cloninger CR, ed.), Washington, DC: American Psychiatric Press. pp. 439-462.
11. Coryell W, Endicott J, Andreasen NC, Keller MB, Clayton PJ, Hirschfeld RMA, et al. (1988) Depression and panic attacks: The significance of overlap as reflected in follow-up and family study data. Am J Psychiatry 145:293-300.
12. Dalery J, Bouhassira M, Kress J-P, Lancrenon S, Tafani A, Hantouche EG (1995) Agitated-anxious versus blunted-retarded major depressions: Different clinical effects of fluoxetine. Encephale 21:217-225.
13. Davidson JR, Miller RD, Turnball CD (1982) Atypical depression. Arch Gen Psychiatry 35:527-534.
14. Fawcett J, Zajecka JM, Kravitz HM (1989) Fluoxetine versus amitriptyline in adult outpatients with major depression. Curr Ther Clin Exp, 45:821-832.
15. Feighner JP, Cohn JB (1985) A comparative trial of fluoxetine and amitriptyline in patients with major depressive disorder. J Clin Psychiatry 45:369-372.
16. Filtcau MJ, Baruch P, Lapierre YD, Bakish D, Blanchard A (1995) SSRIs in anxious-agitated depression: A post-hoc analysis of 279 patients. Int Clin Psychopharmacol 10:51-54.
17. Frances A, Manning D, Marin D, Kocsis J, McKinney K, Hall W, Kline M (1992) Relationship of anxiety and depression. Psychopharmacology (Berl) 106 (Suppl.):S82-S86.
18. Garcia AR (1986) Epidemiology of depression in Latin America. Psychopathology (Switzerland) 19 (Suppl. 2):22-25.
19. Gibbons RD, Clark DC, Kupfer DJ (1993) Exactly what does the Hamilton depression rating scale measure? J Psychiatric Res 27:259-273.
20. Guy W (1976) ECDEU Assessments Manual for Psychopharmacology. Rockville, MD: NIMH.
21. Joyce PR, Paykel ES (1989) Predictors for drug response in depression. Arch Gen Psychiatry 46:89-99.
22. Klein DF (1993) Mixed anxiety and depression, for and against. Encephale 19:493-495.
23. Liebowitz MR, Keller MB (1993) Depression with anxiety and atypical depression. J Clin Psychiatry 54:10-15.
24. Liebowitz MR, Quitkin FM, Stewart JH, McGrath PJ, Harrison W, Rabkin J, et al. (1988) Antidepressant specificity in atypical depression. Arch Gen Psychiatry 45:000-000.
25. Otto MW, Pollack MH, Fava M, Uccello R, Rosenbaum JF (1995) Elevated anxiety sensitivity index scores in patients with major depression: Correlates and changes with antidepressant treatment. J Anxiety Disord 9:117-123.
26. Parker G, Wilhelm K, Asghari A (1997) Early onset depression: The relevance of anxiety. Early Onset Depression: The Relevante of Anxiety. 32:30-37.
27. Partiot A, Jouvent R, Pierson A, Brauch P, Beuzen JN, Ammar S, Widlocher D (1997) Are there differential effects of fluoxetine in retarded/blunted affect versus agitated/anxious depressives? A clinical study. Eur Psychiatry 12:21-27.
28. Robinson DS, Nies A, Ravaris CL, Lamborn KR (1973) The monamine oxidase inhibitor, phenelzine, in the treatment of depressive anxiety states. Arch Gen Psychiatry 29:407-413.
29. Roth M, Gurney C, Garside R, Kerr T (1972) Studies in the classification of affective disorders: The relationship between anxiety states and depressive illness. Br J Psychiatry 12:147-161.
30. Schapira KM, Rogh M, Kerr T (1972) The prognosis of affective disorders: The differentiation of anxiety states from depressive illness. Br J Psychiatry 121:175-181.
31. Schatzberg AF (1995) Fluoxetine in the treatment of comorbid anxiety and depression. J Clin Psychiatry 13:2-12.
32. Tollefson GD, Holman SL, Sayler ME, Potvin JH (1994) Fluoxetine, placebo, and tricyclic antidepressants in major depression with and without anxious features. J Clin Psychiatry 55:50-59.
33. Van Valkenburg C, Akiskal HS, Puzantian V, Rosenthal T (1984) Anxious depressions: Clinical, family history, and naturalistic outcomes. Comparisons with panic and major depressive disorders. J Affect Disord 6:67-82.
34. WHO (1992) The ICD-10 Classification of Mental and Behavioural Disorders. Clinical Descriptions and Diagnostic Guidelines. Geneva: World Health Organization.
35. Young JPR, Coleman A, Lader MH (1987) A controlled comparison of fluoxetine and amitriptyline in depressed outpatients. Br J Psychiatry 150:340-377.
36. Zinbarg RE, Barlow DH, Liebowitz M, Street L, Broadhead E, Katon W, et al. (1994) The DSM-IV field trial for mixed anxiety-depression. Am J Psychiatry 151:1153-1162.
37. Zisook S, Schuchter SR, Gallagher T (1993) Atypical depression in an outpatient psychiatric population. Depression 1:268-274.