Intracellular and cell surface heterotypic associations of human leukocyte antigen-DR and human invariant chain

Human Immunology

Volumn 60, Issue 11, 1999, Pages 1101-1112

  Triantafilou, Kathy ^a   Triantafilou, Martha ^a   Wilson, Keith M ^b   Cherry, Richard J ^a   Fernandez, Nelson ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

CD74; Heterotypic associations; HLA DM; HLA DR; Surface invariant chain

Indexed keywords

HLA DR ANTIGEN;

ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CELL SURFACE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; GOLGI COMPLEX; HLA SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; CELL COMPARTMENTATION; CELL LINE; CELL MEMBRANE; GOLGI APPARATUS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-D ANTIGENS; HLA-DR ANTIGENS; HUMANS; INTRACELLULAR FLUID; MACROMOLECULAR SUBSTANCES; MICROSCOPY, CONFOCAL; TRANSFECTION;

EID: 0032711217     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(99)00097-X     Document Type: Article

References (34)

1. Germain R.N., Margulies D.H. The biochemistry and cell biology of antigen processing and presentation. Ann Rev Immunol. 11:1993;403.
2. Jones P.P., Murphy D.H., Hewgill D., McDevitt H.O. Detection of a common polypeptide chain in I-A and I-E subregion immunoprecipitates. Mol Immunol. 16:1978;51.
3. Marks M.S., Blum J.S., Cresswell P. Invariant chain trimers are sequestered in the rough endoplasmic-reticulum in the absence of association with HLA class-II antigens. J Cell Biol. 111:1990;2519.
4. Roche P.A., Cresswell P. Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding. Nature. 345:1990;615.
5. Bakke O., Bremnes B., Hardersen H., Madsen T. MHC class II associated invariant chain contains a sorting signal for endosomal compartments. Cell. 63:1990;707.
6. Lotteau V., Teyton L., Peleraux A., Nilsson T., Karlsson L., Schmid S.L., Quaranta V., Peterson P.A. Intracellular-transport of class-II MHC molecules directed by invariant chain. Nature. 348:1990;600.
7. Anderson M.S., Miller J. Invariant chain can function as a chaperone protein for class-II major histocompatibility complex-molecules. Proc Natl Acad Sci USA. 89:1992;258.
8. Tulp A., Verwoerd D., Dobberstein B., Ploegh H.L., Pieters J. Isolation and characterization of the intracellular MHC class-II compartment. Nature. 369:1994;120.
9. Rudensky A.Y., Prestonhurlburt P., Al Ramadi B.K., Rothbard J., Janeway C.A. Truncation variants of peptides isolated from MHC class-II molecules suggest sequence motifs. Nature. 359:1992;429.
10. Rudensky A.Y., Prestonhurlburt P., Hong S.C., Barlow A., Janeway C.A. Sequence-analysis of peptides bound to MHC class-II molecules. Nature. 353:1991;622.
11. Hunt D.F., Henderson R.A., Shabanowitz J., Sakaguchi K., Michel H., Sevilir N., Cox A.L., Appella E., Engelhard V.H. Peptides presented to the immune-system by the murine class-II major histocompatibility complex molecule-I-a(D). Science. 256:1992;1817.
12. Chicz R.M., Urban R.G., Gorga J.C., Vignali D.A., Lane W.S., Strominger J.L. Characterization of naturally processed self peptides bound to HLA-DR alleles. J Cell Biochem. 122:1993;259.
13. Freisewinkel I.M., Schenck K., Koch N. The segment of invariant chain that is critical for association with major histocompatibility complex class-II molecules contains the sequence of a peptide eluted from class-II polypeptides. Proc Natl Acad Sci USA. 90:1993;216.
14. Romagnoli P., Germain R.N. The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class-II folding, transport, and peptide occupancy. J Exp Med. 180:1994;1107.
15. Ghosh P., Amaya M., Mellins E., Wiley D.C. The structure of an intermediate in class-II MHC maturation - CLIP bound to HLA-DR3. Nature. 378:1995;457.
16. Denzin L.K., Robbins N.F., Carboynewcomb C., Cresswell P. Assembly and intracellular-transport of HLA-DM and correction of the class-II antigen-processing defect in T2 cells. Immunity. 1:1994;595.
17. Morris P., Shaman J., Attaya M., Amaya M., Goodman S., Bergman C., Monaco J.J., Mellins E. An essential role for HLA-DM in antigen presentation by class-II major histocompatibility molecules. Nature. 368:1994;551.
18. Fling S.P., Arp B., Pious D. HLA-DMA and HLA-DMB genes are both required for MHC class-II peptide complex-formation in antigen-presenting cells. Nature. 368:1994;554.
19. Sloan V.S., Cameron P., Porter G., Gammon M., Amaya M., Mellins E., Zaller D.M. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature. 375:1995;802.
20. Sherman M.A., Weber D.A., Jensen P.E. DM enhances peptide binding to class-II MHC by release of invariant chain-derived peptide. Immunity. 3:1995;197.
21. Denzin L.K., Cresswell P. HLA-DM induces CLIP dissociation from MHC class-II alpha-beta dimers and facilitates peptide loading. Cell. 82:1995;155.
22. Martin W.D., Hicks G.G., Mendiratta S.K., Leva H.I., Ruley H.E., Vankaer L. H2-M mutant mice are defective in the peptide loading of class-II molecules, antigen presentation, and T-cell repertoire selection. Cell. 84:1996;543.
23. Wraight C.J., Vanendert P., Moller P., Lipp J., Ling N.R., Maclennan I.M., Koch N., Moldenhauer G. Human major histocompatibility complex class-II invariant chain is expressed on the cell-surface. J Biol Chem. 265:1990;5783.
24. Koch N., Moldenhauer G., Hofmann W.J., Moller P. Rapid intracellular pathway gives rise to cell-surface expression of the MHC class-II-associated invariant chain (CD74). J Immunol. 147:1991;259.
25. Wilson K.M., Labeta M.O., Pawelec G., Fernandez N. Cell surface expression of human histocompatibility leukocyte antigen (HLA) class II-associated invariant chain (CD74) does not always correlate with cell surface expression of HLA class II molecules. Immunology. 79:1993;331.
26. Smith P.R., Wilson K.M., Morrison I.E.G., Cherry R.J., Fernandez N. Imaging of individual cell surface MHC antigens using fluorescent particles. Fernandez N., Butcher G. MHC Biochemistry and Genetics. Practical Approach Series. 1996;131-151 Oxford University Press.
27. Epstein A.L., Marder R.J., Winter J.N., Fox R.I. Two new monoclonal antibodies (LN1, LN2) reactive with B5 formalin-fixed, paraffin-embedded tissues with follicular center and mantle zone human B lymphocytes and derived tumours. J Immunol. 133:1984;1028.
28. Dodi A.I., Brett S., Nordeng T., Sidhu S., Batchelor R.J., Lombardi G., Bakke O., Lechler R.I. The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell-line. Eur J Immunol. 24:1994;1632.
29. Henne C., Schwenk F., Koch N., Moller P. Surface expression of the invariant chain (CD74) is independent of concomitant expression of major histocompatibility complex class-II antigens. Immunol. 84:1995;177.
30. Weiss S., Bogen B. MHC class-II-restricted presentation of intracellular antigen. Cell. 64:1991;767.
31. Brooks A., Hartley S., Kjernielsen L., Perera J., Goodnow C.C., Basten A., McCluskey J. Class-II-restricted presentation of an endogenously derived immunodominant T-cell determinant of hen egg lysozyme. Proc Natl Acad Sci USA. 88:1991;258.
32. Chen B.P., Rothbard J., Parham P. Apparent lack of MHC restriction in binding of class-I HLA molecules to solid-phase peptides. J Exp Med. 172:1990;568.
33. Nuchtern J.G., Biddison W.E., Klausner R.D. Class-II MHC molecules can use the endogenous pathway of antigen presentation. Nature. 343:1990;74.
34. Adorini L., Moreno J., Momburg F., Hammerling G.J., Gery J.C., Valli A., Fuchs S. Exogenous peptides compete for the presentation of endogenous antigens to major histocompatibility complex class II-restricted T-cells. J Exp Med. 174:1991;940.