Identification of Treponema pallidum subspecies pallidum in a 200-year- old skeletal specimen

Journal of Infectious Diseases

Volumn 180, Issue 6, 1999, Pages 2060-2063

  Kolman, Connie J ^a,d   Centurion Lara, Arturo ^b   Lukehart, Sheila A ^b   Owsley, Douglas W ^c   Tuross, Noreen C ^a  

^a Smithsonian Center for Materials Research and Education   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c SMITHSONIAN INSTITUTION   (United States)

^d NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN ANTIBODY REACTION; ARTICLE; BACTERIAL INFECTION; BACTERIUM IDENTIFICATION; DNA POLYMORPHISM; NONHUMAN; PRIORITY JOURNAL; SYPHILIS; TREPONEMA PALLIDUM;

ANTIGENS, BACTERIAL; BASE SEQUENCE; BONE AND BONES; DNA, BACTERIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTORY, 18TH CENTURY; HUMANS; IMMUNOGLOBULIN G; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYNESIA; SEQUENCE ANALYSIS, DNA; SYPHILIS; TREPONEMA PALLIDUM;

EID: 0032710628     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315151     Document Type: Article

References (14)

1. 1. Centurion-Lara A, Castro C, Castillo R, Shaffer JM, Van Voorhis WC, Lukehart SA. The flanking region sequences of the 15-kDa lipoprotein gene differentiate pathogenic treponemes. J Infect Dis 1998;177:1036-40.
2. 2. Fraser CM, Norris SJ, Weinstock GM, et al. Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science 1998;281:375-88.
3. 3. Kolman CJ, Tuross N. Ancient DNA analysis of humans. Am J Phys Anthropol (in press).
4. 4. Purcell BK, Swancutt MA, Radolf JD. Lipid modification of the 15 kDa major membrane immunogen of Treponema pallidum. Mol Microbiol 1990;4:1371-79.
5. 5. Rothschild BM, Rothschild C. Treponemal disease revisited: skeletal discriminators for yaws, bejel, and venereal syphilis. Clin Infect Dis 1995;20: 1402-08.
6. 6. Williams HU. Human paleopathology. Arch Pathol 1929;7:839-902.
7. 7. Steinbock RT. Paleopathological diagnosis and interpretation. Springfield, IL: Thomas Books, 1976:137.
8. 8. Ortner DJ, Putschar WGJ. Identification of pathological conditions in human skeletal remains. Washington, DC: Smithsonian Institution Press, 1985: 104-234.
9. 9. Salo WL, Aufderheide AC, Buikstra J, Holcomb TA. Identification of Mycobacterium tubercolosis DNA in a pre-Columbian Peruvian mummy. Proc Natl Acad Sci USA 1994;91:2091-4.
10. 10. Drancourt M, Aboudharam G, Signoli M, Dutour O, Raoult D. Detection of 400-year-old Yersinia pestis DNA in human dental pulp: an approach to the diagnosis of ancient septicemia. Proc Natl Acad Sci USA 1998;95: 12637-40.
11. 11. Jackson PJ, Hugh-Jones ME, Adair DM, et al. PCR analysis of tissue samples from the 1979 Sverdlovsk anthrax victims: the presence of multiple Bacillus anthracis strains in different victims. Proc Natl Acad Sci USA 1998;95: 1224-29.
12. 12. Owsley DW, Gill GW, Ousley SD. Biological effects of European contact on Easter Island. In: Larsen CS, Milner GR. In the wake of contact: biological responses to conquest. New York: Wiley-Liss, 1994:161-77.
13. 13. Höss M, Dilling A, Currant A, Pääbo S. Molecular phylogeny of the extinct ground sloth Mylodon darwinii. Proc Natl Acad Sci USA 1996;93:181-5.
14. 14. Baker BJ, Armelagos GJ. The origin and antiquity of syphilis. Curr Anthropol 1988;29:703-37.