Antigiardial and immunostimulatory effect of Piper longum on giardiasis due to Giardia lamblia

Phytotherapy Research

Volumn 13, Issue 7, 1999, Pages 561-565

  Tripathi, D M ^a   Gupta, N ^a   Lakshmi, V ^a   Saxena, K C ^a   Agrawal, A K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Giardia lamblia; Giardiasis; Herbal drug; Immunostimulation; Piper longum

Indexed keywords

ANTIPROTOZOAL AGENT; HERBACEOUS AGENT; IMMUNOSTIMULATING AGENT; PIPER LONGUM EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; EXPERIMENTAL INFECTION; FEMALE; GIARDIA LAMBLIA; GIARDIASIS; HEMAGGLUTINATION; MACROPHAGE MIGRATION; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHAGOCYTOSIS; PLAQUE FORMING CELL; TROPHOZOITE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIPROTOZOAL AGENTS; GIARDIA LAMBLIA; GIARDIASIS; MACROPHAGES, PERITONEAL; MICE; PLANT EXTRACTS; PLANTS, MEDICINAL;

ANIMALIA; GIARDIA INTESTINALIS; PIPER LONGUM;

EID: 0032709870     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199911)13:7<561::AID-PTR479>3.0.CO;2-W     Document Type: Article

References (21)

1. Agarwal, A. K., Singh, M., and Gupta, N. et al. (1994). Management of giardiasis by an immuno-modulatory herbal drug - Pippali Rasayana. Ethnopharmacol 44, 143-146.
2. Aggarwal, A., Bhatia, A., Naik, S. R., and Vinayak, V. K. (1983). Variable virulence of isolates of Giardia lamblia (in mice). Ann. Trop. Med. Parasitol. 77, 328-332.
3. Agrawal, A. K., Tripathi, D. M., and Sahai, R. et al. (1997) Management of giardiasis by a herbal drug Pippali Rasayana: A clinical study. J. Ethnopharmacol. 56, 233-236.
4. Ament, M. E., and Rubin, C. E. (1972). Relation of giardiasis to abnormal intestinal structure and function in gastro-intestinal immuno-deficiency syndromes. Gastroenterology 62, 216-226.
5. Black, R. E., Dykes, A. C., Sinclair, S. P., and Wells, J. G. (1977). Giardiasis in day care centres: evidence of person to person transmission. Pediatrics 60, 486-491.
6. Chopra, R. N., Nayar, S. L., and Chopra, I. C. (1956). Glossary of Indian Medicinal Plants, p. 194. CSIR Publications, New Delhi.
7. D'Cruz, J. L., Nimbkar, A. Y., and Kokati, C. K. (1980). Evaluation of fruits of Piper (Linn) and Adhatoda vasica (nees) for antihelminthic activity. Indian Drugs 17, 99-101.
8. Farthing, M. J. G. (1989) Host-parasite interactions in human Giardiasis. Quart. J. Med. 70, 191-204.
9. Jerne, N. K., and Nordin, A. A. (1963). Plaque formation in agar by single antibody producing cell. Science 140, 405.
10. Jokipil, L., and Jokipil, A. M. M. (1979). Single dose metronidazole and tinidazole as therapy of giardiasis: success rates, side effects, drug absorption and elimination. J. Infect., Dis. 140, 984-988.
11. Leijh, P. C. J., Van der Barselar, M. T., and Van Furth, R. (1977). Kinetics of phagocytosis and intracellular killing of Candida albicans by human granulocytes and monocytes. Infect. Immun. 17, 313-318.
12. Manavalan, P., and Singh, J. (1979). Chemical and some pharmacological studies on leaves of Piper longum (Linn). Indian J. Pharmaceut. Sci. 41, 190-191.
13. Pandeya, G. (Ed.) (1983). Caraka Chikitsa Part II, Kashi Sanskrit Series 194, pp. 29-34. Chaukhambha Sanskrit Sansthan, Varanasi, India.
14. Rege, N., Dahanukar, S., and Karandikar, S. M. (1984). Hepatoprotective effects of Piper longlum against carbon tetrachloride induced liver damage. Indian Drugs 21, 569-572.
15. Satyavati, G. V., Gupta, A. K., and Tandon, A. K. (1987). Medicinal Plants of India, vol. 2, pp. 426-456. ICMR Publications, New Delhi.
16. Saxena, K. C., Puri, A., Sumati, R., Saxena, R., and Saxena, R. P. (1991). Macrophage migration as an index of immune status. Immunol. Invest. 20, 431-440.
17. Shastri, K. N., and Chaturvedi, G. N. (1986). Caraka Samhita Compilation 13th ed. Chi 1-1/7, 8. Chaukhamba Vidya Bhawan, Varanasi, India.
18. Stavitsky, A. B. (1954). Micro methods for the study of proteins and antibodies. I. Procedure and general applications of haemagglutination and haemagglutination reactions with tannic acid and proteins treated red blood cells. J. Immunol. 72, 360-367.
19. Upcroft, J. A., and Upcroft, P. (1993). Drug resistance and Giardia. Parasitol. Today 9, 187-190.
20. Walia, B. N. S., Ganguly, N. K., and Mahajan, R. C. (1986). Morbidity in pre-school Giardia cyst excretors. Trop. Geogr. Med. 38, 367-370.
21. Warrier, P. K. (1981). The importance of black piper in Ayurveda. Indian Spices 18, 3-5.