Tuberculin sensitivity: Conversions and reversions in a rural African population

International Journal of Tuberculosis and Lung Disease

Volumn 3, Issue 11, 1999, Pages 962-975

  Fine, Paul E M ^a   Bruce, J ^a   Ponnighaus, J M ^b,c   Nkhosa, P ^b   Harawa, A ^b   Vynnycky, E ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b KARONGA PREVENTION STUDY   (Malawi)

^c Vogtlandklinikum Plauen ^*  (Germany)

Author keywords

Annual risk of infection; Delayed type hypersensitivity; Epidemiology; Malawi; Tuberculin; Tuberculosis

Indexed keywords

BCG VACCINE;

ADOLESCENT; ADULT; ARTICLE; DELAYED HYPERSENSITIVITY; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; INFECTION RISK; MAJOR CLINICAL STUDY; MALAWI; MALE; PREVALENCE; PRIORITY JOURNAL; TUBERCULIN TEST; TUBERCULOSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; HYPERSENSITIVITY, DELAYED; INFANT; LONGITUDINAL STUDIES; MALAWI; MALE; MIDDLE AGED; MODELS, STATISTICAL; RURAL POPULATION; SENSITIVITY AND SPECIFICITY; TUBERCULIN TEST; TUBERCULOSIS;

EID: 0032709641     PISSN: 10273719     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Huebner R E, Schein M F, Bass J B. The tuberculin skin test. Clin Infect Dis 1993; 17: 968-975.
2. Bleiker M A, Sutherland I, Styblo K, ten Dam H G, Mislenovic O. Guidelines for estimating the risks of tuberculous infection from tuberculin test results in a representative sample of children. Bull Int Union Tuberc Lung Dis 1989; 64 (2): 7-12.
3. Palmer C E, Edwards L B. Identifying the tuberculous infected: the dual-test technique. JAMA 1968; 205: 167-169.
4. Rieder H L. Methodological issues in the estimation of the tuberculosis problem from tuberculin surveys. Tubercle Lung Dis 1995; 76: 114-121.
5. de March-Ayuela P. Choosing an appropriate criterion for true or false conversion in serial tuberculin testing. Am Rev Respir Dis 1990; 141: 815-820.
6. Thompson N J, Glassroth J L, Snider D E Jr, Farer L S. The booster phenomenon in serial tuberculin testing. Am Rev Respir Dis 1979; 119: 587-597.
7. Grzybowski S, Allen E A. The challenge of tuberculosis in decline a study based on the epidemiology of tuberculosis in Ontario, Canada. Am Rev Respir Dis 1964; 90: 707-720.
8. Perez-Stable E J, Flaherty D, Schecter G, Slutkin G, Hopewell P C. Conversion and reversion of tuberculin reactions in nursing home residents. Am Rev Respir Dis 1988; 137: 8011-804.
9. Felten M K, Van der Merwe C A. Random variation in tuberculin sensitivity in schoolchildren. Serial skin testing before and after preventive treatment for tuberculosis. Am Rev Respir Dis 1989; 140: 1001-1006.
10. Ponnighaus J M, Fine P E M, Bliss L, Sliney I J, Bradley D J, Rees R J W. The Lepra Evaluation Project (LEP), an epidemiological study of leprosy in Northern Malawi. I. Methods. Lepr Rev 1987; 58: 359-375.
11. Ponnighaus J M, Fine P E M, Gruer P J K, et al. The Karonga Prevention Trial: a leprosy and tuberculosis vaccine trial in Northern Malawi. I. Methods of the vaccination phase. Lepr Rev 1993; 64: 338-356.
12. Fine P E M, Ponnighaus J M, Maine N. The distribution and implications of BCG scars, with particular reference to a population in Northern Malawi. Bull World Health Organ 1989; 67: 35-42.
13. Styblo K, Muwinge H, Chum H J, et al. The second round of the national tuberculin survey in Tanzania, 1988-1992. TSRU Progress Report 1995; 1: 140-191.
14. Bosman M C J, Swai O B, Kwamanga D O, Agwanda R, Idukitta G, Misljenovic O. National tuberculin survey of Kenya, 1986-1990. Int J Tuberc Lung Dis 1998; 2: 272-280.
15. Misljenovic O. Report of the results of the base-line tuberculin survey in schoolchildren in Malawi, January - April 1994. TSRU Progress Report 1996: 101-110.
16. American Thoracic Society. Diagnostic standards and classification of tuberculosis and other mycobacterial diseases 1981. Am Rev Respir Dis 1981; 123: 1-16.
17. American Thoracic Society. Diagnostic standards and classification of tuberculosis. Am Rev Respir Dis 1990; 142: 725-735.
18. Muench H. Catalytic Models in epidemiology. Cambridge, Massachusetts: Harvard University Press, 1959.
19. Styblo K, Meijer J, Sutherland I. The transmission of tubercle bacilli. Its trend in a human population. Tuberculosis Surveillance Research Unit Report No. 1. Bull Int Union Tuberc 1969; 42: 5-104.
20. Ponnighaus J M, Mwanjasi L J, Fine P E M, et al. Is HIV infection a risk factor for leprosy? Int J Lepr Other Mycobact Dis 1991; 59: 221-228.
21. Tala-Heikkila M, Nurmela T, Mislenovic O, Bleiker M A, Tala E. Sensitivity to PPD tuberculin and M. scrofulaceum sensitin in schoolchildren BCG vaccinated at birth. Tubercle Lung Dis 1992; 7: 87-93.
22. Peltola H, Mohamed NM, Kataja M, et al. Risk of infection with Mycobacterium tuberculosis among children and mothers in Somalia. Clin Infect Dis 1993; 18: 106-111.
23. WHO Tuberculosis Research Office. Further studies of geographic variation in naturally acquired tuberculin sensitivity. Bull World Health Organ 1955; 12: 63-83.
24. Ponnighaus J M, Fine P E M. Sensitization studies with potential leprosy vaccine preparations in Northern Malawi. Int J Lepr Other Mycobact Dis 1986; 54: 25-37.
25. Ponnighaus J M, Fine P E M, Sterne J A C, et al. Efficacy of BCG against leprosy and tuberculosis in Northern Malawi. Lancet 1992; 339: 636-639.
26. Karonga Prevention Trial Group. Randomized controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Lancet 1996; 348: 17-24.
27. Fine P E M, Sterne J A C, Ponnighaus J M, Rees R J W. Delayed-type hypersensitivity, mycobacterial vaccines and protective immunity. Lancet 1994; 344: 1245-1249.
28. Tuberculosis Prevention Trial Madras. Trial of BCG vaccines in South India for tuberculosis prevention. Indian J Med Res 1980; 72 (Suppl): 1-74.
29. Palmer C E. BCG vaccination and tuberculin allergy. Lancet 1952; 10 May: 935-940.
30. Roelsgaard E, Iversen E, Blocher C. Tuberculosis in tropical Africa an epidemiological study. Bull World Health Organ 1964; 30: 459-518.
31. Nyboe J. Interpretation of tuberculosis infection age curves. Bull World Health Organ 1957; 17: 319-339.
32. Neuenschwander B E, Kim S J, Zwahlen M, Engel R R, Rieder H L. Trends in the prevalence of infection with Mycobacterium tuberculosis in Korea from 1965 to 1995 - an analysis of seven surveys by mixture models. TSRU Progress Report 1999; II: 13-46.
33. Gay N J. Analysis of serological surveys using mixture models: application to a survey of parvovirus B19. Stat Med 1996; 15: 1567-1573.
34. Mayurnath S, Vallishayee R S, Radhamani M P, Prabhakar R. Prevalence study of tuberculous infection over fifteen years, in a rural population of Chingleput district (south India). Indian J Med Res 1991; 93: 74-80.
35. Sutherland I. The effect of tuberculin reversion upon the estimate of the annual risk of tuberculous infection. Bull Int Union Tuberc 1971; XLV: 115-118.
36. Narain R, Nair S S, Chandrasekhar P, Ramantha Rao G. Problems connected with estimating the incidence of tuberculosis infection. Bull World Health Organ 1966; 34: 605-622.
37. Glynn J R, Warndorff D K, Fine P E M, Msiska G K, Munthali M M, Ponnighaus J M. The impact of HIV on morbidity and mortality in sub-Saharan Africa: a study in rural Malawi and review of the literature. Health Trans Rev 1998; 7: 75-87.
38. Press W H, Teukolsky S A, Vetterling W T, Flannery B P. Numerical recipes in C: the art of scientific computing. Cambridge, UK: Cambridge University Press, 1992.