The practical significance of potential biases in estimates of the AIDS incubation period distribution in the UK register of HIV seroconverters

AIDS

Volumn 13, Issue 14, 1999, Pages 1943-1951

  Porter, Kholoud ^a,c   Johnson, Anne M ^b   Phillips, Andrew N ^b   Darbyshire, Janet H ^a  

^a Med Res Cncl Clinical Trials Unit   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c MRC CLINICAL TRIALS UNIT   (United Kingdom)

Author keywords

Bias; Cohort; Incubation period; Late entry; Progression; Seroconverters

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DATA ANALYSIS; DEATH; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCUBATION TIME; KAPOSI SARCOMA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SEROCONVERSION;

EID: 0032708910     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199910010-00018     Document Type: Article

References (30)

1. UK Register of HIV Seroconverters Steering Committee. The UK Register of HIV Seroconverters: methods and analytical issues. Epidem & Infec 1996, 117:305-312.
2. UK Register of HIV Seroconverters Steering Committee. The AIDS incubation period in the UK estimated from a national register of HIV seroconverters. AIDS 1998, 12:659-667.
3. UK Register of HIV Seroconverters Steering Committee. How soon after HIV seroconversion is anti-retroviral therapy initiated? AIDS 1999, 13:1241-1247.
4. Clayton C, Hills M. Statistical Models in Epidemiology. Oxford: Oxford University Press; 1993.
5. Gill ON, Nicoll A, Molesworth AM, et al. Combining sequential HIV prevalence with mortality estimates to measure recent HIV incidence in England and Wales. XII International Conference on AIDS, Geneva 1998 [abstract 43440].
6. Crowe SM, Carlin JB, Stewart KI, Luca CR, Hoy JF. Predictive value of CD4 lymphocyte numbers for the development of opportunistic infections and malignancies in HIV-infected persons. J Acquir Immune Defic Syndr 1991, 4:770-776.
7. Brettle RP, McNeil AJ, Burns S, et al. Progression of HIV: follow up of Edinburgh injecting drug users with narrow seroconversion intervals in 1983-1985. AIDS 1996, 10:419-430.
8. van Benthem BHB, Veugelers PJ, Schechter MT, Kaldor JM, Page-Shafer KA, van Griensven GJP. Modelling the AIDS incubation time: evaluation of the right censoring strategies. AIDS 1997, 11:834-835.
9. The Italian Seroconversion Study. Disease progression and early predictors of AIDS in HIV-seroconverted injecting drug users. AIDS 1992, 6:421-426.
10. Rezza C, Lazzarin A, Angarano C, et al. The natural history of HIV infection in intravenous drug users: risk of disease progression in a cohort of seroconverters. AIDS 1989, 3:87-90.
11. Rezza G, Lazzarin A, Angarano G, et al. Risk of AIDS in HIV seroconverters: a comparison between intravenous drug users and homosexual males. Eur J Epidemiol 1990, 6:99-101.
12. Evans BG. The extent of under-reporting of AIDS cases in England, Wales and Northern Ireland. June 1995, CDSC, DM thesis.
13. Norton J, Elford J, Sherr L, Miller R, Johnson MA. Repeat HIV testers at a London same-day testing clinic. AIDS 1997, 11:773-781.
14. Dorrucci M, Rezza G, Vlahov D, et al. Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users. Italian Seroconversion Study. AIDS 1995, 9:597-604.
15. Pedersen C, Lindhardt BØ, Jensen BL, et al. Clinical course of primary HIV infection: consequences for subsequent course of infection. BMJ 1989, 299:154-157.
16. 6/I, AIDS, and death from AIDS? BMJ 1994, 309:1535-1537.
17. Sinicco A, Fora R, Sciandra M, Luchini A, Caramello P, Gioannini P. Risk of developing AIDS after primary acute HIV-1 infection. J Acquir Immune Defic Syndr 1993, 6:575-581.
18. Darby SC, Rizza CR, Doll R, Spooner RJD, Stratton IM, Thakrar B. Incidence of AIDS and excess mortality associated with HIV in haemophiliacs in the United Kingdom: report on behalf of the directors of haemophilia centres in the United Kingdom. BMJ 1989, 298:1064-1068.
19. Goedert JJ, Kessler CM, Aledort LM, et al. A prospective study of human immunodeficiency virus type 1 infection and the development of AIDS in subjects with haemophilia. N Engl J Med 1989, 321:1141-1148.
20. Eyster ME, Gail MH, Ballard JO, Al-Mondhiry H, Goedert JJ. Natural history of human immunodeficiency virus infections in haemophiliacs: effects of T-cell subsets, platelet counts, and age. Ann Int Med 1987, 107:1-6.
21. Ragni MV, Kingsley LA. Cumulative risk for AIDS and other HIV outcomes in a cohort of haemophiliacs in Western Pennsylvania. J Acquir Immune Defic Syndr 1990, 3:708-713.
22. Schinaia N, Ghirardini A, Chiarotti F, Gringeri A, Mannucci PM. Progression to AIDS among Italian HIV-seropositive haemophiliacs. AIDS 1991, 5:385-391.
23. Flegg PJ. The natural history of HIV infection: a study in Edinburgh drug users. J Infect 1994, 29:311-321.
24. Hessol NA, Koblin BA, van Griensven GJP, et al. Progression of human immunodeficiency virus type 1 (HIV-1) infection among homosexual men in hepatitis B vaccine trial cohorts in Amsterdam, New York City, and San Francisco, 1976-1991. Am J Epidemiol 1994, 139:1077-1087.
25. Veugelers PJ, Page KA, Tindall B, et al. Determinants of HIV disease progression among homosexual men registered in the Tricontinental Seroconverter Study. Am J Epidemiol 1994, 140:747-758.
26. Sinicco A, Fora R, Raiteri R, et al. Is the clinical course of HIV-1 changing? Cohort study. BMJ 1997, 314:1232-1237.
27. Taylor JMG, Schwartz K, Detels R. The time from infection with Human Immunodeficiency Virus (HIV) to the onset of AIDS. J Infect Dis 1986, 154:694-697.
28. Muñoz A, Xu J. Models for the incubation of AIDS and variations according to age and period. Stat Med 1996, 15:2459-2473.
29. Keet IPM, Veugelers PJ, Koot M, et al. Temporal trends of the natural history of HIV-1 infection following seroconversion between 1984 and 1993 [letter]. AIDS 1996, 10:1601-1602.
30. Porter K, Fairley CK, Wall PG, et al. AIDS defining diseases in the UK: the impact of PCP prophylaxis and twelve years of change. Int J STD & AIDS 1996, 7:252-257.