Endothelial adhesion molecule expression and its inhibition by recombinant bactericidal/permeability-increasing protein are influenced by the capsulation and Lipooligosaccharide structure of Neisseria meningitidis

Infection and Immunity

Volumn 67, Issue 11, 1999, Pages 5626-5633

  Dixon, Garth L J ^a   Heyderman, Robert S ^b   Kotovicz, Karolena ^a   Jack, Dominic L ^a   Andersen, Svein R ^c   Vogel, Ulrich ^d   Frosch, Matthias ^d   Klein, Nigel ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b Dept Anat Sch Med Sci U   (United Kingdom)

^c Churchill Hospital   (United Kingdom)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CELL ADHESION MOLECULE; ENDOTOXIN ANTIBODY; INTERCELLULAR ADHESION MOLECULE 1; OLIGOSACCHARIDE; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BACTERIAL MEMBRANE; BACTERICIDAL ACTIVITY; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM INJURY; HUMAN; HUMAN CELL; INFLAMMATION; INFLAMMATORY CELL; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032707708     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.67.11.5626-5633.1999     Document Type: Article

References (43)

1. Andersen, S. R., K. Bry, K. Thorseng, and E. Jantzen. 1996. Heterogeneity of lipopolysaccharides of Neisseria meningitidis revealed by thin-layer chromatography combined with monoclonal antibodies. J. Microbiol. Methods 25:187.
2. Arditi, M., J. Zhou, S. H. Huang, P. M. Luckett, M. N. Marra, and K. S. Kim. 1994. Bactericidal/permeability-increasing protein protects vascular endothelial cells from lipopolysaccharide-induced activation and injury. Infect. Immun. 62:3930-3936.
3. 2-terminal fragment with isolated LPS and intact Proteus mirabilis and Escherichia coli. Infect. Immun. 62:259-265.
4. Carlos, T. M., and J. M. Harlan. 1994. Leukocyte-endothelial adhesion molecules. Blood 84:2068-2101.
5. Dustin, M. L., and T. A. Springer. 1988. Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to cultured endothelial cells. J. Cell Biol. 107:321-331.
6. Gazzano-Santoro, H., J. B. Parent, L. Grinna, A. Horwitz, T. Parsons, G. Theofan, P. Elsbach, J. Weiss, and P. J. Conlon. 1992. High-affinity binding of the bactericidal/permeability-increasing protein and a recombinant amino-terminal fragment to the lipid A region of lipopolysaccharide. Infect. Immun. 60:4754-4761.
7. Hammerschmidt, S., C. Birkholz, U. Zahringer, B. D. Robertson, J. van Putten, O. Ebeling, and M. Frosch. 1994. Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis. Mol. Microbiol. 11:885-896.
8. Hammerschmidt, S., R. Hilse, J. P. van Putten, R. Gerardy-Schahn, A. Unkmeir, and M. Frosch. 1996. Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element. EMBO J. 15:192-198.
9. Hammerschmidt, S., A. Muller, H. Sillmann, M. Muhlenhoff, R. Borrow, A. Fox, J. van Putten, W. D. Zollinger, R. Gerardy-Schahn, and M. Frosch, 1996. Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease. Mol. Microbiol. 20:1211-1220.
10. Heyderman, R. S., N. J. Klein, O. A. Daramola, S. Hammerschmidt, M. Frosch, B. D. Robertson, M. Levin, and C. A. Ison. 1997. Induction of human endothetial tissue factor expression by Neisseria meningitidis: the influence of bacterial killing and adherence to the endothelium. Microb. Pathog. 22:265-276.
11. Hill, W. R., and T. D. Kinney. 1947. The cutaneous lesions in acute meningococcaemia. JAMA 134:513.
12. Huang, K., D. M. Fishwild, H. M. Wu, and R. L. Dedrick. 1995. Lipopolysaccharide-induced E-selectin expression requires continuous presence of LPS and is inhibited by bactericidal/permeability-increasing protein. Inflammation 19:389-404.
13. Jarvis, G. A., J. Li, and K. Swanson. 1999. Invasion of human mucosal epithelial cells by Neisseria gonorrhoeae upregulates expression of intercellular adhesion molecule 1 (ICAM-1). Infect. Immun. 67:1149-1156.
14. Jones, D. M. 1995. Epidemiology of meningococcal disease in Europe and the USA, p. 71-114. In K. Cartwright (ed.), Meningococcal disease. John Wiley & Sons Ltd., Chichester, United Kingdom.
15. Jones, D. M., R. Borrow, A. J. Fox, S. Gray, K. A. Cartwright, and J. T. Poolman. 1992. The lipooligosaccharide immunotype as a virulence determinant in Neisseria meningitidis. Microb. Pathog. 13:219-224.
16. Kahler, C. M., L. E. Martin, G. C. Shin, M. M. Rahman, R. W. Carlson, and D. S. Stephens. 1998. The (alpha2-→8)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serum. Infect. Immun. 66:5939-5947.
17. Karmann, K., W. Min, W. C. Fanslow, and J. S. Pober. 1996. Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1. J. Exp. Med. 184:173-182.
18. Kirsch, E. A., R. P. Barton, L. Kitchen, and B. P. Giroir. 1996. Pathophysiology, treatment and outcome of meningococcemia: a review and recent experience. Pediatr. Infect. Dis. J. 15:967-978.
19. Kirschning, C. J., H. Wesche, A. T. Merrill, and M. Rothe. 1998. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J. Exp. Med. 188:2091-2097.
20. Klein, N. J., C. A. Ison, M. Peakman, M. Levin, S. Hammerschmidt, M. Frosch, and R. S. Heyderman. 1996. The influence of capsulation and lipooligosaccharide structure on neutrophil adhesion molecule expression and endothelial injury by Neisseria meningitidis. J. Infect. Dis. 173:172-179.
21. Kotowicz, K., R. E. Callard, K. Friedrich, D. J. Matthews, and N. Klein. 1996. Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor. Int. Immunol. 8:1915-1925.
22. Marra, M. N., C. G. Wilde, J. E. Griffith, J. L. Snable, and R. W. Scott. 1990. Bactericidal/permeability-increasing protein has endotoxin-neutralizing activity. J. Immunol. 144:662-666.
23. Mercier, J. C., F. Beaufils, J. F. Hartmann, and D. Azema. 1988. Hemodynamic patterns of meningococcal shock in children. Crit. Care Med. 16:27-33.
24. Miles, A. A., S. S. Misia, and J. O. Irwin. 1932. The estimation of the bactericidal power of blood. Journal Hyg. Camb. 38:732.
25. Naumann, M., T. Rudel, B. Wieland, C. Bartsch, and T. F. Meyer. 1998. Coordinate activation of activator protein 1 and inflammatory cytokines in response to Neisseria gonorrhoeae epithelial cell contact involves stress response kinases. J. Exp. Med. 188:1277-1286.
26. Naumann, M., S. Wessler, C. Bartsch, B. Wieland, and T. F. Meyer. 1997. Neisseria gonorrhoeae epithelial cell interaction leads to the activation of the transcription factors nuclear factor kappaB and activator protein 1 and the induction of inflammatory cytokines. J. Exp. Med. 186:247-258.
27. 2+ and tumor necrosis factor-induced degranulation in adherent human neutrophils. J. Biol. Chem. 265:14358-14363.
28. Rock, F. L., G. Hardiman, J. C. Timans, R. A. Kastelein, and J. F. Bazan. 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95:588-593.
29. Sotto, M. N., B. Langer, S. S. Hoshino, and T. de Brito. 1976. Pathogenesis of cutaneous lesions in acute meningococcemia in humans: light, immunofluorescent, and electron microscopic studies of skin biopsy specimens. J. Infect. Dis. 133:506-514.
30. Springer, T. A. 1994. Traffic signals for lymphocyte recirculation and leukocyte migration: the multistep paradigm. Cell 76:301-314.
31. Tsai, C. M., C. E. Frasch, E. Rivera, and H. D. Hochstein. 1989. Measurement of lipopolysaccharide (endotoxin) in meningococcal protein and polysaccharide preparations for vaccines usage. J. Biol. Stand. 17:249-258.
32. Virji, M., H. Kayhty, D. J. Ferguson, C. Alexandrescu, J. E. Heckels, and E. R. Moxon. 1991. The vole of pili in the interactions of pathogenic Neisseria with cultured human endothelial cells. Mol. Microbiol. 5:1831-1841.
33. Virji, M., K. Makepeace, D. J. Ferguson, M. Achtman, and E. R. Moxon. 1993. Meningococcal Opa and Ope proteins: their role in colonization and invasion of human epithelial and endothelial cells. Mol. Microbiol. 10:499-510.
34. Virji, M., K. Makepeace, D. J. Ferguson, M. Achtman, J. Sarkari, and E. R. Moxon. 1992. Expression of the Opc protein correlates with invasion of epithelial and endothelial cells by Neisseria meningitidis. Mol. Microbiol. 6:2785-2795.
35. Virji, M., K. Makepeace, I. R. Peak, D. J. Ferguson, M. P. Jennings, and E. R. Moxon. 1995. Opc- and pilus-dependent interactions of meningococci with human endothelial cells: molecular mechanisms and modulation by surface polysaccharides. Mol. Microbiol. 18:741-754.
36. Vogel, U., H. Claus, G. Heinze, and M. Frosch. 1997. Functional characterization of an isogenic meningococcal alpha-2,3-sialyltransferase mutant: the role of lipooligosaccharide sialylation for serum resistance in serogroup B meningococci. Med. Microbiol. Immunol. Berlin 184:159-166.
37. Vogel, U., H. Claus, G. Heinze, and M. Frosch. 1999. Role of lipopolysaccharide sialylation in serum resistance of serogroup B and C meningococcal disease isolates. Infect. Immun. 67:954-957.
38. Vogel, U., S. Hammerschmidt, and M. Frosch. 1996. Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitidis serogroup B are prerequisites for virulence of meningococci in the infant rat. Med. Microbiol. Immunol. Berlin 185:81-87.
39. von Asmuth, E. J., M. A. Denlener, V. Bazil, M. G. Bouma, J. F. Leeuwenberg, and W. A. Buurman. 1993. Anti-CD14 antibodies reduce responses of cultured human endothelial cells to endotoxin. Immunology 80:78-83.
40. Weiss, J., Q. S. Beckerdite, and P. Elsbach. 1980. Resistance of gramnegative bacteria to purified bactericidal leukocyte proteins: relation to binding and bacterial lipopolysaccharide structure. J. Clin. Investig. 65:619-628.
41. 2-terminal fragment cause killing of serum-resistant gram-negative bacteria in whole blood and inhibit tumor necrosis factor release induced by the bacteria. J. Clin. Investig. 90:1122-1130.
42. Wright, S. D. 1999. Toll, a new piece in the puzzle of innate immunity. J. Exp. Med. 189:605-609.
43. Yang, R. B., M. R. Mark, A. Gray, A. Huang, M. H. Xie, M. Zhang, A. Goddard, W. I. Wood, A. L. Gurney, and P. J. Godowski. 1998. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 395:284-288.