Evaluation of cytoreductive surgery with pelvic and paraaortic lymphadenectomy and intermittent cisplatin-based combination chemotherapy for improvement of long-term survival in ovarian cancer

European Journal of Gynaecological Oncology

Volumn 20, Issue 5-6, 1999, Pages 361-366

  Yokoyama, Yoshihito ^a   Sakamoto, T ^a   Sato, S ^a   Saito, Y ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Intermittent chemotherapy; Long term survival; Ovarian cancer; Pelvic and paraaortic lymphadenectomy

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER REGRESSION; CANCER STAGING; CANCER SURVIVAL; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; EVALUATION; FEMALE; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MULTIVARIATE ANALYSIS; OVARY CANCER; PARAAORTIC LYMPH NODE; PELVIS LYMPHADENECTOMY; PROGNOSIS;

ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; AORTA; CHEMOTHERAPY, ADJUVANT; CISPLATIN; FEMALE; HUMANS; LYMPH NODE EXCISION; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; OVARIAN NEOPLASMS; PELVIS;

EID: 0032707046     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Piver M. S., Lele S. B., Marchetti D. L., Baker T. R., Tsukada Y., Emrich L.: "The impact of aggressive debulking surgery and cisplatin-based chemotherapy on progression-free survival in stage III and IV ovarian carcinoma". J. Clin. Oncol., 1988, 6, 983.
2. Burghardt E., Pickel H., Lahousen M., Stettner H.: "Pelvic lymphadenectomy in operative treatment of ovarian cancer". Am. J. Obster. Gynecol., 1986, 155, 315.
3. Chen S. S., Bochner R.: "Assessment of morbidity and mortality in primary cytoreductive surgery for advanced ovarian carcinoma". Gynecol. Oncol., 1985, 20, 190.
4. Berek J. S., Hacker N. F., Lagrasse L. D., Leuchter R. S.: "Lower urinary tract resection as part of cytoreductive surgery for ovarian cancer". Gynecol. Oncol., 1982, 13, 87.
5. Wu P., Qu J., Lang J., Huang R., Tang M., Lian L.: "Lymph node metastases of ovarian cancer: a preliminary surgery of 74 cases of lymphadenectomy". Am. J. Obstet. Gynecol., 1986, 155, 1103.
6. Louie K. G., Ozols R. F., Myers C. E., Ostchega Y., Jenkins J., Howser D., Young R. C.: "Long-term results of a cisplatin-containing combination chemotherapy regimen for the treatment of advanced ovarian carcinoma". J. Clin. Oncol., 1986, 4, 1579.
7. Conte P. F., Bruzzone M., Chiara S., Sertoli M. R., Daga M. G., Rubagotti A., Conio A. et al.: "A randomized trial comparing cisplatin plus cyclophosphamide versus cisplatin, doxorubicin and cyclophosphamide in advanced ovarian cancer". J. Clin. Oncol., 1986, 4, 965.
8. Sutton G., Steman F. B., Einhorn L. H., Roth L. M., Blessing J. A., Ehrlich C. E.: "Ten-year follow-up of patients receiving cisplatin, doxorubicin and cyclophosphamide chemotherapy for advanced epithelial ovarian carcinoma". J. Clin. Oncol., 1989, 7, 223.
9. Inoue M., Nakanishi K., Ueda G., Tanizawa O.: "Intermittent intensive combination chemotherapy with cisplatin, doxorubicin, and cyclophosphamide (cyclic PAC chemotherapy) for ovarian cancer". Am. J. Clin. Oncol., 1992, 15, 1.
10. Di Re F., Baiocchi G., Fontanelli R., Grosso G., Cobellis L., Raspagliesi R., Di Re E.: "Systematic pelvic and paraaortic lymphadenectomy for advanced ovarian cancer: prognosis significance of node metastases". Gynecol. Oncol., 1996, 62, 360.
11. Spirtos N. M., Gross G. M., Freddo J. L., Ballon S. C.: "Cytoreductive surgery in advanced epithelial cancer of the ovary: the impact of aortic and pelvic lymphadenectomy". Gynecol. Oncol., 1995, 56, 345.
12. Scarabelli C., Gallo A., Zarrelli A., Visentin C., Campagnutta E.: "Systematic pelvic and paraaortic lymphadenectomy during cytoreductive surgery in advanced ovarian cancer: potential benefit on survival". Gynecol. Oncol., 1995, 56, 328.
13. Piver M. S., Baker T.: "The potential for optimal (<2 cm) cytoreductive surgery in advanced ovarian carcinoma at a tertial medical center. A prospective study". Gynecol. Oncol., 1986, 24, 1.
14. Ludescher C., Weger A. R., Lindholm J.: "Prognostic significance of tumor cell morphometry, histopathology and clinical parameters in advanced ovarian carcinoma". Int. J. Gynecol. Pathol., 1990, 9, 343.
15. Nishimura H., Hamaguchi K., Miyahara K., Tazaki T., Tateno N., Yakushiji M.: "The current therapeutic approach to advanced ovarian cancer". Acta Obstet. Gynecol. Jpn., 1990, 42, 1691.
16. Kigawa J., Minagawa Y., Itamochi H., Kanamori Y., Ishihara H., Terakawa N.: "Retroperitoneal lymphadenectomy, including the para-aortic nodes in patients with stage III ovarian cancer". Am. J. Clin. Oncol., 1994, 17, 230.
17. Kikkawa F., Ishikawa H., Tamakoshi K., Suganuma N., Mizuno K., Kawai M., Arii Y. et al.: "Prognostic evaluation of lymphadenectomy for epithelial ovarian cancer". J. Surg. Oncol., 1995, 60, 227.
18. Belinson J., McClure M., Ashikaga T., Krakoff I. H.: "Treatment of advanced and recurrent ovarian carcinoma with cyclophosphamide, doxorubicin, and cisplatin". Cancer, 1984, 54, 1983.
19. Omura G., Blessing J. A., Ehrlich C. E.: "A randomized trial of cyclophosphamide and doxorubicin with or without cisplatin in advanced ovarian carcinoma. A gynecologic oncology group study". Cancer, 1986, 57, 1725.
20. Burghardt E., Lahousen M., Stettner H.: "The significance of pelvic and para-aortic lymphadenectomy in the operative treatment of ovarian cancer". Bailliere's Clin. Obstet. Gynecol., 1989, 3, 157.
21. Fukasawa H., Kikkawa K., Kawai M., Arii Y., Tomoda Y: "Lymphadenectomy in stage-III serous cystadenocarcinoma of the ovary". Int. J. Gynecol. Obstet., 1995, 57, 239.
22. Tsuruchi N., Kamura T., Tsukamoto N., Akazawa K., Saito T., Kaku T., To N., Nakano H.: "Relationship between paraaortic lymph node involvement and intraperitoneal spread in patients with ovarian cancer: a multivariate analysis". Gynecol. Oncol., 1993, 49, 51.
23. Burghardt E., Girardi F., Lahousen M., Tamussino K., Stettner H.: "Pattern of pelvic and paraaortic node involvement in ovarian cancer". Gynecol. Oncol., 1991, 40, 103.
24. Onda T., Yoshikawa H., Yasugi T., Mishima M., Nakagawa S., Yamada M., Matsumoto K., Taketani Y.: "Patients with ovarian carcinoma upstaged to stage III after systematic lymphadenectomy have similar survival to Stage I/II patients and superior survival to other Stage III patients". Cancer, 1998, 83, 1555.