Functional characterization of monoclonal antibodies to interferon-tau

Hybridoma

Volumn 18, Issue 5, 1999, Pages 399-405

  Swann, Sandra L ^a   Bazer, Fuller W ^b   Villarete, Lorelie H ^c   Chung, Albert ^c   Pontzer, Carol H ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c Pepgen Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CYTOKINE ANTIBODY; INTERFERON RECEPTOR; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HL 100; MONOCLONAL ANTIBODY HL 127; MONOCLONAL ANTIBODY HL 129; MONOCLONAL ANTIBODY HL 98; RECEPTOR SUBTYPE; TAU INTERFERON; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTIVIRAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; MITOSIS INHIBITION; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0032706836     PISSN: 0272457X     EISSN: None     Source Type: Journal    
DOI: 10.1089/hyb.1999.18.399     Document Type: Article

References (22)

1. Bazer FW, Spencer TE, and Ott TL: Placental inteferons. Am J Reprod Immunol 1996;35:297-308.
2. Pontzer CH, Torres BA, Vallet JL, Bazer FW, and Johnson HM: Antiviral activity of the pregnancy recognition hormone ovine trophoblast protein-1. Biochem Biophys Res Com 1988;152:801-807.
3. Pontzer CH, Bazer FW, and Johnson HM: Antiproliferative activity of a pregnancy hormone, ovine trophoblast protein-1. Cancer Res 1991;51:5304-5307.
4. Subramaniam PS, Khan SA, Pontzer CH, and Johnson HM: Differential recognition of the type 1 interferon receptor by interferons τ and α is responsible for their disparate cytotoxicities. Proc Natl Acad Sci USA 1995;92:12270-12274.
5. Soos JM, Schiffenbauer J, Johnson HM, and Pontzer CH: Interferon τ: A potential treatment for inflammatory central nervous system diseases. In: Interferon Therapy of Multiple Sclerosis. Reder AT, (Ed.). Marcel Dekker, Inc., New York, 1997, pp. 479-498.
6. Jarpe MA, Johnson HM, Bazer FW, Ott TL, Curto EV, Krishna NR, and Pontzer CH: Predicted structural motif of IFN τ. Protein Eng 1994;7:863-867.
7. Radhakrishnan R, Walter LJ, Subramaniam PS, Johnson HM, and Walter MR: Crystal structure of ovine interferon-τ at 2.1 Å resolution. J Mol Biol 1999;286:151-162.
8. Stewart HJ, McCann SHE, Barker PJ, Lee KE, Lamming GE, and Flint APF: Interferon sequence homology and receptor binding activity of ovine trophoblast antileuteolytic protein. J Endocrinol 1987;115:R13-R15.
9. Harlow E, and Lane D: Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1988.
10. Van Heeke G, Ott TL, Strauss A, Ammaturo D, and Bazer FW: High yield expression and secretion of the ovine pregnancy recognition hormone interferon-τ by Pichia Pastoris. J Interferon Cytokine Res 1996;16:119-126.
11. Pontzer CH, Ott TL, Bazer FW, and Johnson HM: Localization of an antiviral site on the pregnancy recognition hormone, ovine trophoblast protein-1. Proc Natl Acad Sci USA 1990;87:5945-5949.
12. Pontzer CH, Ott TL, Bazer FW, and Johnson HM: Structure function studies with interferon tau evidence for multiple active sites. J Interferon Res 1994;14:133-141.
13. Pontzer CH, and Johnson HM: Measurement of interferons. Meth Neurosci 1995;24:3-9.
14. Roberts RM, Liu L, Guo Q, Leaman D, and Bixby J: The evolution of the type I interferons. J Interferon Cytokine Res 1988;18:805-816.
15. Benoit P, Maguire D, Plavec I, Kocher H, Tovey M, and Meyer F: A monoclonal antibody to recombinant human IFN-α receptor inhibits biologic activity of several species of human IFN-α, IFN-β and IFN-ω. J Immunol 1993;150:707-716.
16. Senda T, Saitoh S-I, and Mitsui Y: Refined crystal structure of recombinant murine interferon-β at 2.15 Å resolution. J Mol Biol 1995;253:187-207.
17. 2b revealed by X-ray crystallography. Structure 1996;4:1453-1463.
18. Hansen TR, Kazemi M, Keisler DH, Malathy P, Imakawa K, Roberts RM: Complex binding of the embryonic interferon, ovine trophoblast protein-1, to endometrial receptors. J Interferon Res 1989;9:215-225.
19. Barasoain I, Portoles A, Aramburu JF, and Rojo JM: Antibodies against a peptide representative of a conserved region of human IFNα: Differential effects on the antiviral and antiproliferative effects of IFN. J Immunol 1989;143:507-512.
20. Arora T, Floyd-Smith G, Espy MJ, and Jelinek DF: Dissociation between IFN-α-induced anti-viral and growth signaling pathways. J Immunol 1999;162:3289-3297.
21. Zhu D, Ott TL, and Bazer FW: Enzyme-linked immunosorbent assay for ovine interferon-τ. J Interferon Cytokine Res 1996;16: 147-150.
22. Gutterman JU: Cytokine therapeutics: Lessons from interferon α. Proc Natl Acad Sci 1994;91:1198-1205.