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Volumn 11, Issue 6, 1999, Pages 615-620

IL-4 receptor mutations

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR;

EID: 0032705435     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(99)00026-6     Document Type: Review
Times cited : (13)

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    • This report implicates SOCS-1 in the negative regulation of IL-4 signal transduction. The expression of SOCS-1 but not SOCS-2 was able to inhibit IL-4-induced activation of a Stat6 reporter in transient transfection. Stable cell lines expressing SOCS-1 showed decreased levels of Jak-1 and Stat6 activation
    • Losman J.A., Chen X.P., Hilton D., Rothman P. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J Immunol. 162:1999;3770-3774. This report implicates SOCS-1 in the negative regulation of IL-4 signal transduction. The expression of SOCS-1 but not SOCS-2 was able to inhibit IL-4-induced activation of a Stat6 reporter in transient transfection. Stable cell lines expressing SOCS-1 showed decreased levels of Jak-1 and Stat6 activation.
    • (1999) J Immunol , vol.162 , pp. 3770-3774
    • Losman, J.A.1    Chen, X.P.2    Hilton, D.3    Rothman, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.