Selective effect of malathion on blood coagulation versus locomotor activity

Journal of Environmental Pathology, Toxicology and Oncology

Volumn 18, Issue 3, 1999, Pages 203-211

  Sweeney, Marva I ^a   Lyon, Martha E ^b,c  

^a UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Activated partial thromboplastin time; Blood coagulation; Central nervous system; Locomotion; Malathion; Organophosphates; Prothrombin time

Indexed keywords

MALATHION;

ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING; BODY MOVEMENT; CONTROLLED STUDY; FEMALE; LOCOMOTION; MALE; NEUROTOXICITY; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; RAT; REARING; STEREOTYPY;

ANIMALS; BEHAVIOR, ANIMAL; BLOOD COAGULATION; FEMALE; INJECTIONS, INTRAPERITONEAL; INSECTICIDES; MALATHION; MALE; MOTOR ACTIVITY; PARTIAL THROMBOPLASTIN TIME; RATS; RATS, WISTAR; TIME FACTORS;

EID: 0032704689     PISSN: 07318898     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Koelle GB. Pharmacology and toxicology of organophosphates. In: Ballantyne B, Marrs TC, eds. Clinical and experimental toxicology of organophosphates and carbamates. Oxford: Butterworth-Heinemann, 1992: 35-39.
2. Richardson RJ. Assessment of the neurotoxic potential of chloropyrifos relative to other organophosphorus compounds: a critical review of the literature. J Toxicol Environ Health 1995; 44:135-165.
3. Marrs TC. Organophosphate poisoning. Pharmacol Therapeut 1993; 58:51-66.
4. Reiter L, Talons G, Woolley D. Acute and subacute parathion treatment: effects on cholinesterase activities and learning in mice. Toxicol Appl Pharmacol 1973; 25:582-588.
5. Gordon CJ. Thermoregulation in laboratory mammals and humans exposed to anticholinesterase agents. Neurotoxicol Teratol 1994; 16:427-453.
6. Lotti M. Central neurotoxicity and behavioral effects of anticholinesterases. In: Ballantyne B, Marrs TC, eds. Clinical and experimental toxicology of organophosphates and carbamates. Oxford: Butterworth-Heinemann, 1992: 75-83.
7. Lox CD. Effects of acute pesticide poisoning on blood clotting in the rat. Ecotoxicol Environ Safety 1983; 7:451-454.
8. Lox CD. Short term malathion ingestion and blood clotting in the rat. J Environ Pathol Toxicol Oncol 1985; 6:51-55.
9. Lox CD. The effects of short term diazinon exposure on blood clotting activity in the rat. J Environ Pathol Toxicol Oncol 1987; 7:67-71.
10. Lox CD, Davis JR. The effects of long term malathion or diazinon ingestion on the activity of hepatic synthesized clotting factors. Ecotoxicol Environ Safety 1983; 7:546-551.
11. Murray JC, Stein F, McGlothin JC, McClain KL. Prolongation of the prothrombin time after organophosphate poisoning. Pediatric Emerg Care 1994; 10:289-290.
12. Gupta AK, Muni A, Ranjan-Dalela RC. Toxic effects of chlordane and malathion on certain hematological parameters of a freshwater teleost, Notopterus notopterus. J Environ Biol 1995; 16:219-233.
13. Khattack IUD, Hafeez MA. Effect of malathion on blood parameters of the fish, Cyprinion watsoni. Pakistan J Zool 1996; 28:45-49.
14. Keadtisuke S, Dheranetra W, Nakatsugawa T, Fukuto TR. Liver damage induced by malathion impurities. Toxicol Lett 1990; 52:35-46.
15. MSDS information sheet for malathion from Supelco, 1997.