메뉴 건너뛰기




Volumn 19, Issue 11, 1999, Pages 1229-1236

Identification of functional domains of the interferon-induced enzyme PKR in cells lacking endogenous PKR

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON; PROTEIN KINASE;

EID: 0032704442     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999099312885     Document Type: Article
Times cited : (5)

References (52)
  • 2
    • 0031915809 scopus 로고    scopus 로고
    • Signal transduction in the interferon system
    • HAQUE, S.J., and WILLIAMS, B.R.G. (1998). Signal transduction in the interferon system. Semin. Oncol. 25 (Suppl. 1), 14-22.
    • (1998) Semin. Oncol. , vol.25 , Issue.SUPPL. 1 , pp. 14-22
    • Haque, S.J.1    Williams, B.R.G.2
  • 3
    • 0032417696 scopus 로고    scopus 로고
    • Indentification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays
    • DER, S.D., ZHOU, A., WILLIAMS, B.R., and SILVERMAN, R.H. (1998). Indentification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays. Proc. Natl. Acad. Sci. USA 95, 15623-15628.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15623-15628
    • Der, S.D.1    Zhou, A.2    Williams, B.R.3    Silverman, R.H.4
  • 4
    • 0000990272 scopus 로고
    • B.N. Fields and D.M. Knipe (eds.). New York: Raven Press
    • JOKLIK, W.K. (1990). In: Virology. (B.N. Fields and D.M. Knipe (eds.). New York: Raven Press, pp. 383-410.
    • (1990) Virology , pp. 383-410
    • Joklik, W.K.1
  • 5
    • 0025739093 scopus 로고
    • Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • SAMUEL, C.E. (1991). Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183, 1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 6
    • 0029007407 scopus 로고
    • PKR: A new name and new roles
    • PROUD, C.G. (1995). PKR: a new name and new roles. Trends Biochem. Sci. 20, 241-246.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 241-246
    • Proud, C.G.1
  • 7
    • 0025298202 scopus 로고
    • Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon
    • MEURS, E.F., CHONG, K., GALABRU, J., THOMAS, N.S.B., KERR, Y.M., WILLIAMS, B.R.G., and HOVANESSIAN, A.G. (1990). Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell 62, 379-390.
    • (1990) Cell , vol.62 , pp. 379-390
    • Meurs, E.F.1    Chong, K.2    Galabru, J.3    Thomas, N.S.B.4    Kerr, Y.M.5    Williams, B.R.G.6    Hovanessian, A.G.7
  • 8
    • 0002352428 scopus 로고    scopus 로고
    • Protein kinases that phosphorylate eIF2 and EIF2B, and their role in eukaryotic cell translational control
    • J.W.B. Hershey, M.B. Mathews, and N. Sonenberg (eds.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • CLEMENS, M.J. (1996). Protein kinases that phosphorylate eIF2 and EIF2B, and their role in eukaryotic cell translational control. In: Translational Control. J.W.B. Hershey, M.B. Mathews, and N. Sonenberg (eds.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 139-172.
    • (1996) Translational Control , pp. 139-172
    • Clemens, M.J.1
  • 9
    • 0030725442 scopus 로고    scopus 로고
    • The double-stranded RNA-dependent protein kinase PKR: Structure and function
    • CLEMENS, M.J., and ELIA, A. (1997). The double-stranded RNA-dependent protein kinase PKR: structure and function. J. Interferon Cytokine Res. 17, 503-524.
    • (1997) J. Interferon Cytokine Res. , vol.17 , pp. 503-524
    • Clemens, M.J.1    Elia, A.2
  • 10
    • 0023878562 scopus 로고
    • The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2
    • ROWLANDS, A.G., PANNIERS, R., and HENSHAW, E.C. (1988). The catalytic mechanism of guanine nucleotide exchange factor action and competitive inhibition by phosphorylated eukaryotic initiation factor 2. J. Biol. Chem. 263, 5526-5533.
    • (1988) J. Biol. Chem. , vol.263 , pp. 5526-5533
    • Rowlands, A.G.1    Panniers, R.2    Henshaw, E.C.3
  • 11
    • 0017370502 scopus 로고
    • Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis
    • FARREL, P.J., BALKOW, K., HUNT, T., JACKSON, R.J., and TRACHSEL, H. (1977). Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis. Cell 11, 187-200.
    • (1977) Cell , vol.11 , pp. 187-200
    • Farrel, P.J.1    Balkow, K.2    Hunt, T.3    Jackson, R.J.4    Trachsel, H.5
  • 12
    • 0026929934 scopus 로고
    • Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth
    • MEURS, E.F., WATANABE, Y., KADEREIT, S., BARBER, G.N., BARBER, M.G., CHANG, K., WILLIAMS, B.R.G., and HOVANESSIAN, A.G. (1992). Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66, 5805-5814.
    • (1992) J. Virol. , vol.66 , pp. 5805-5814
    • Meurs, E.F.1    Watanabe, Y.2    Kadereit, S.3    Barber, G.N.4    Barber, M.G.5    Chang, K.6    Williams, B.R.G.7    Hovanessian, A.G.8
  • 13
    • 0026465921 scopus 로고
    • Protein phosphorylation in translational control
    • PROUD, C.G. (1992). Protein phosphorylation in translational control. Curr. Top. Cell. Regul. 32, 2443-369.
    • (1992) Curr. Top. Cell. Regul. , vol.32 , pp. 2443-3369
    • Proud, C.G.1
  • 14
    • 0001016282 scopus 로고    scopus 로고
    • Interactions between viruses and the cellular machinery for protein synthesis
    • J.W.B. Hershey, M.B. Mathews, and N. Sonenberg (eds.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • MATHEWS, M.B. (1996). Interactions between viruses and the cellular machinery for protein synthesis. In: Translational Control. J.W.B. Hershey, M.B. Mathews, and N. Sonenberg (eds.). Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, pp. 505-548.
    • (1996) Translational Control , pp. 505-548
    • Mathews, M.B.1
  • 15
    • 0027157746 scopus 로고
    • The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus
    • LEE, S.B., and ESTEBAN, M. (1993). The interferon-induced double-stranded RNA-activated human p68 protein kinase inhibits the replication of vaccinia virus. Virology 193, 1037-1041.
    • (1993) Virology , vol.193 , pp. 1037-1041
    • Lee, S.B.1    Esteban, M.2
  • 16
    • 0030467465 scopus 로고    scopus 로고
    • Regulated expression of the interferon-induced protein kinase p68 (PKR) by vaccinia virus recombinants inhibits the replication of vesicular stomatitis virus but not that of poliovirus
    • LEE, S.B., BABLANIAN, R., and ESTEBAN, M. (1996). Regulated expression of the interferon-induced protein kinase p68 (PKR) by vaccinia virus recombinants inhibits the replication of vesicular stomatitis virus but not that of poliovirus. J. Interferon Cytokine Res. 16, 1073-1078.
    • (1996) J. Interferon Cytokine Res. , vol.16 , pp. 1073-1078
    • Lee, S.B.1    Bablanian, R.2    Esteban, M.3
  • 17
    • 0027308224 scopus 로고
    • The interferon induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells
    • LEE, S.B., MELKOVA, Z., YAN, W., WILLIAMS, B.R.G., HOVANESSIAN, A.G., and ESTEBAN, M. (1993). The interferon induced double-stranded RNA-activated human p68 protein kinase potently inhibits protein synthesis in cultured cells. Virology 192, 380-385.
    • (1993) Virology , vol.192 , pp. 380-385
    • Lee, S.B.1    Melkova, Z.2    Yan, W.3    Williams, B.R.G.4    Hovanessian, A.G.5    Esteban, M.6
  • 18
    • 0026701570 scopus 로고
    • Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase
    • KOROMILAS, A.E., ROY, S., BARBER, G.N., KATZE, M.G., and SONEMBERG, N. (1992). Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase. Science 257, 1685-1689.
    • (1992) Science , vol.257 , pp. 1685-1689
    • Koromilas, A.E.1    Roy, S.2    Barber, G.N.3    Katze, M.G.4    Sonemberg, N.5
  • 19
  • 20
    • 0021684617 scopus 로고
    • Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells
    • PETRYSHYN, R., CHEN, J.J., and LONDON, Y.M. (1984). Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells. J. Biol. Chem. 259, 14736-14742.
    • (1984) J. Biol. Chem. , vol.259 , pp. 14736-14742
    • Petryshyn, R.1    Chen, J.J.2    London, Y.M.3
  • 21
    • 0028290902 scopus 로고
    • The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis
    • LEE, S.B., and ESTEBAN, M. (1994). The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis. Virology 199, 491-496.
    • (1994) Virology , vol.199 , pp. 491-496
    • Lee, S.B.1    Esteban, M.2
  • 22
    • 0344731406 scopus 로고    scopus 로고
    • Induction of apoptosis by the dsRNA dependent protein kinase (PKR) involves eIF2α and NF-κB
    • GIL, J., ALCAMI, J., and ESTEBAN, M. (1999). Induction of apoptosis by the dsRNA dependent protein kinase (PKR) involves eIF2α and NF-κB. Mol. Cell. Biol. 19, 4653-4663.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4653-4663
    • Gil, J.1    Alcami, J.2    Esteban, M.3
  • 23
    • 0028852619 scopus 로고
    • Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate-early gene induction
    • MUNDSCHAU, L.J., and FALLER, D.V. (1995). Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate-early gene induction. J. Biol. Chem. 207, 3100-3106.
    • (1995) J. Biol. Chem. , vol.207 , pp. 3100-3106
    • Mundschau, L.J.1    Faller, D.V.2
  • 25
    • 17444449609 scopus 로고    scopus 로고
    • Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: Role of IRF-1 and NF-kappaB
    • KUMAR, A., YANG, Y.-L., FLATI, V., DER, S., KADEREIT, S., DEB, A., HAQUE, J., REIS, L., WEISSMANN, C., and WILLIAMS, B.R.G. (1997). Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB. EMBO J. 1997 16, 406-416.
    • (1997) EMBO J. 1997 , vol.16 , pp. 406-416
    • Kumar, A.1    Yang, Y.-L.2    Flati, V.3    Der, S.4    Kadereit, S.5    Deb, A.6    Haque, J.7    Reis, L.8    Weissmann, C.9    Williams, B.R.G.10
  • 26
    • 0032936285 scopus 로고    scopus 로고
    • Double-stranded RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53
    • CUDDIHY, A.R., LI, S., TAM, N.W., WONG, A.M., TAYA, Y., ABRAHAM, N., BELL, J.C., and KOROMILAS, A.E. (1999). Double-stranded RNA-activated protein kinase PKR enhances transcriptional activation by tumor suppressor p53. Mol. Cell. Biol. 19, 2475-2484.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2475-2484
    • Cuddihy, A.R.1    Li, S.2    Tam, N.W.3    Wong, A.M.4    Taya, Y.5    Abraham, N.6    Bell, J.C.7    Koromilas, A.E.8
  • 27
    • 0028924758 scopus 로고
    • Structural requirements for dsRNA-binding, dimerization and activation of the human eIF-2α kinase DAI in Saccharomyces cerevisiae
    • ROMANO, P.R., GREEN, S.R., BARBER, G.N., MATHEWS, M.B., and HINNEBUSCH, A.G. (1995). Structural requirements for dsRNA-binding, dimerization and activation of the human eIF-2α kinase DAI in Saccharomyces cerevisiae. Mol. Cell. Biol. 15, 365-378.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 365-378
    • Romano, P.R.1    Green, S.R.2    Barber, G.N.3    Mathews, M.B.4    Hinnebusch, A.G.5
  • 29
    • 0027105279 scopus 로고
    • Two RNA binding motifs in the double-stranded RNA activated protein kinase, DAI
    • GREEN, S.R., and MATHEWS, M.B. (1992). Two RNA binding motifs in the double-stranded RNA activated protein kinase, DAI. Genes Dev. 6, 2478-2490.
    • (1992) Genes Dev. , vol.6 , pp. 2478-2490
    • Green, S.R.1    Mathews, M.B.2
  • 30
    • 0028961190 scopus 로고
    • Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase
    • GREEN, S.R., MANCHE, L., and MATHEWS, M.B. (1995). Two functionally distinct RNA-binding motifs in the regulatory domain of the protein kinase. DAI. Mol. Cell. Biol. 15, 358-364.
    • (1995) DAI. Mol. Cell. Biol. , vol.15 , pp. 358-364
    • Green, S.R.1    Manche, L.2    Mathews, M.B.3
  • 31
    • 0026042013 scopus 로고
    • Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr, protein kinase in a cell-free system
    • KATZE, M.G., WAMBACH, M., WONG, M.-L., GARFINKEL, M., MEURS, E., CHANG, K., WILLIAMS, B.R.G., HOVANESSIAN, A.G., and BARBER, G.N. (1991). Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr, protein kinase in a cell-free system. Mol. Cell. Biol. 11, 5497-5505.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5497-5505
    • Katze, M.G.1    Wambach, M.2    Wong, M.-L.3    Garfinkel, M.4    Meurs, E.5    Chang, K.6    Williams, B.R.G.7    Hovanessian, A.G.8    Barber, G.N.9
  • 32
    • 0040350202 scopus 로고
    • Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase
    • SAMUEL, C.E. (1979). Mechanism of interferon action: phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA 76, 600-604.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 600-604
    • Samuel, C.E.1
  • 33
    • 0029039746 scopus 로고
    • Mechanism of interferon action: Characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase
    • THOMIS, D.C., and SAMUEL, C.E. (1995). Mechanism of interferon action: characterization of the intermolecular autophosphorylation of PKR, the interferon-inducible, RNA-dependent protein kinase. J. Virol. 69, 5195-5198.
    • (1995) J. Virol. , vol.69 , pp. 5195-5198
    • Thomis, D.C.1    Samuel, C.E.2
  • 34
    • 0032530310 scopus 로고    scopus 로고
    • Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation
    • NANDURI, S., CARPICK, B.W., YANG, Y., WILLIAMS, B.R.G., and QIN, I. (1998). Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation. EMBO J. 17, 5458-5465.
    • (1998) EMBO J. , vol.17 , pp. 5458-5465
    • Nanduri, S.1    Carpick, B.W.2    Yang, Y.3    Williams, B.R.G.4    Qin, I.5
  • 35
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • HANKS, S.K., QUINN, A.M., and HUNTER, T. (1988). The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241, 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 36
    • 0027943267 scopus 로고
    • Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domains
    • LEE, S.B., GREEN, S.R., MATHEWS, M.B., and ESTEBAN, M. (1994). Activation of the double-stranded RNA (dsRNA)-activated human protein kinase in vivo in the absence of its dsRNA binding domains. Proc. Natl. Acad. Sci. USA 91, 10551-10555.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10551-10555
    • Lee, S.B.1    Green, S.R.2    Mathews, M.B.3    Esteban, M.4
  • 37
    • 10244257563 scopus 로고    scopus 로고
    • Autophosphorylation sites participate in the activation of the double-stranded RNA activated protein kinase PKR
    • TAYLOR, D.R., LEE, S.B., ROMANO, P.R., MARSHACK, D.R., HINNEBUSCH, A.G., ESTEBAN, M., and MATHEWS, M.B. (1996). Autophosphorylation sites participate in the activation of the double-stranded RNA activated protein kinase PKR. Mol. Cell. Biol. 16, 6295-6302.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6295-6302
    • Taylor, D.R.1    Lee, S.B.2    Romano, P.R.3    Marshack, D.R.4    Hinnebusch, A.G.5    Esteban, M.6    Mathews, M.B.7
  • 38
    • 0031585534 scopus 로고    scopus 로고
    • Interaction of the human protein kinase PKR with the mouse PKR homolog occurs via the N-terminal region of PKR and does not inactivate autophosphorylation activity of mouse PKR
    • RENDE-FOURNIER, R., ORTEGA, L.G., GEORGE, C.X., and SAMUEL, C.E. (1997). Interaction of the human protein kinase PKR with the mouse PKR homolog occurs via the N-terminal region of PKR and does not inactivate autophosphorylation activity of mouse PKR. Virology 238, 410-423.
    • (1997) Virology , vol.238 , pp. 410-423
    • Rende-Fournier, R.1    Ortega, L.G.2    George, C.X.3    Samuel, C.E.4
  • 39
    • 0021345626 scopus 로고
    • General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes
    • MACKETT, M., SMITH, G.L., and MOSS, B. (1984). General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes. J. Virol. 49, 857-864.
    • (1984) J. Virol. , vol.49 , pp. 857-864
    • Mackett, M.1    Smith, G.L.2    Moss, B.3
  • 40
    • 0027231434 scopus 로고
    • Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase
    • BARBER, G.N., WAMBACH, M., WONG, M.L., DEVER, T.E., HINNEBUSCH, A.G., and KATZE, M.G. (1993). Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase. Proc. Natl. Acad. Sci. USA 90, 4621-4625.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4621-4625
    • Barber, G.N.1    Wambach, M.2    Wong, M.L.3    Dever, T.E.4    Hinnebusch, A.G.5    Katze, M.G.6
  • 41
  • 42
    • 0343812093 scopus 로고    scopus 로고
    • The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases
    • LEE, S.B., RODRIGUEZ, D., RODRIGUEZ, J.R., and ESTEBAN, M. (1997). The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases. Virology 231, 81-88.
    • (1997) Virology , vol.231 , pp. 81-88
    • Lee, S.B.1    Rodriguez, D.2    Rodriguez, J.R.3    Esteban, M.4
  • 43
    • 0030585155 scopus 로고    scopus 로고
    • When two strands are better than one: The mediators and modulators of the cellular responses to double-stranded RNA
    • JACOBS, B.L., and LANGLAND, J.O. (1996). When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA. Virology 219, 339-349.
    • (1996) Virology , vol.219 , pp. 339-349
    • Jacobs, B.L.1    Langland, J.O.2
  • 44
    • 85086952956 scopus 로고
    • Mechanism of synthesis of vaccinia virus double-stranded ribonucleic acid in vivo and in vitro
    • COLBY, C., JURALE, C., and KATES, J.R. (1971). Mechanism of synthesis of vaccinia virus double-stranded ribonucleic acid in vivo and in vitro. J. Virol. 7, 220-228.
    • (1971) J. Virol. , vol.7 , pp. 220-228
    • Colby, C.1    Jurale, C.2    Kates, J.R.3
  • 45
    • 0030989529 scopus 로고    scopus 로고
    • Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA
    • CARPICK, B.W., GRAZIANO, V., SCHNEIDER, D., MAITRA, R.K., LEE, K., and WILLIAMS, B.R.G. (1997). Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA. J. Biol. Chem. 272, 9510-9516.
    • (1997) J. Biol. Chem. , vol.272 , pp. 9510-9516
    • Carpick, B.W.1    Graziano, V.2    Schneider, D.3    Maitra, R.K.4    Lee, K.5    Williams, B.R.G.6
  • 46
    • 0029782652 scopus 로고    scopus 로고
    • Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR
    • BEVILACQUA, P.C., and CECH, T.R. (1996). Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR. Biochemistry 35, 9983-9994.
    • (1996) Biochemistry , vol.35 , pp. 9983-9994
    • Bevilacqua, P.C.1    Cech, T.R.2
  • 47
    • 0032480017 scopus 로고    scopus 로고
    • PACT, a protein activator of the interferon-induced protein kinase, PKR
    • PATEL, R.C., and SEN, G.C. (1998). PACT, a protein activator of the interferon-induced protein kinase, PKR. EMBO J. 17, 4379-4390.
    • (1998) EMBO J. , vol.17 , pp. 4379-4390
    • Patel, R.C.1    Sen, G.C.2
  • 48
    • 0030030724 scopus 로고    scopus 로고
    • Mechanism of interferon action: Biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells
    • ORTEGA, L.G., MCCOTTER, M.D., HENRY, G.L., MCCORMACK, S.J., THOMIS, D.C., and SAMUEL, C.E. (1996). Mechanism of interferon action: biochemical and genetic evidence for the intermolecular association of the RNA-dependent protein kinase PKR from human cells. Virology 215, 31-39.
    • (1996) Virology , vol.215 , pp. 31-39
    • Ortega, L.G.1    Mccotter, M.D.2    Henry, G.L.3    Mccormack, S.J.4    Thomis, D.C.5    Samuel, C.E.6
  • 49
    • 0031021425 scopus 로고    scopus 로고
    • A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR
    • WU, S.Y., and KAUFMAN, R.J. (1997). A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR. J. Biol. Chem. 272, 1291-1296.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1291-1296
    • Wu, S.Y.1    Kaufman, R.J.2
  • 50
    • 0030198564 scopus 로고    scopus 로고
    • Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase
    • GEORGE, C.X., THOMIS, D.C., MCCORMACK, S.J., SVAHN, C.M., and SAMUEL, C.E. (1996). Characterization of the heparin-mediated activation of PKR, the interferon-inducible RNA-dependent protein kinase. Virology 221, 180-188.
    • (1996) Virology , vol.221 , pp. 180-188
    • George, C.X.1    Thomis, D.C.2    Mccormack, S.J.3    Svahn, C.M.4    Samuel, C.E.5
  • 51
    • 0031899816 scopus 로고    scopus 로고
    • Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2α kinases PKR and GCN2
    • ROMANO, P.R., GARCIA-BARRIO, M.T., ZHANG, X., WANG, Q., TAYLOR, D.R., ZHANG, F., HERRING, C., MATHEWS, M.B., QIN, J., and HINNEBUSCH, A.G. (1998). Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2α kinases PKR and GCN2. Mol. Cell. Biol. 18, 2282-2297.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2282-2297
    • Romano, P.R.1    Garcia-Barrio, M.T.2    Zhang, X.3    Wang, Q.4    Taylor, D.R.5    Zhang, F.6    Herring, C.7    Mathews, M.B.8    Qin, J.9    Hinnebusch, A.G.10
  • 52
    • 0031897318 scopus 로고    scopus 로고
    • Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor
    • TAN, S.-L., GALE, M.J., Jr., and KATZE, M.G. (1998). Double-stranded RNA-independent dimerization of interferon-induced protein kinase PKR and inhibition of dimerization by the cellular P58IPK inhibitor. Mol. Cell. Biol. 18, 2431-2443.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2431-2443
    • Tan, S.-L.1    Gale Jr., M.J.2    Katze, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.