The effect of atropine in vasovagal syncope induced by head-up tilt testing

European Heart Journal

Volumn 20, Issue 23, 1999, Pages 1745-1751

  Santini, M ^a   Ammirati, F ^a   Colivicchi, F ^a   Gentilucci, G ^a   Guido, V ^a  

^a SAN FILIPPO NERI HOSPITAL   (Italy)

Author keywords

Atropine; Head up tilt testing; Vasovagal syncope

Indexed keywords

ATROPINE; PLACEBO; SODIUM CHLORIDE;

ADULT; ARTICLE; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HEART RATE; HUMAN; HYDRODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; SYNCOPE; TILT TABLE TEST;

EID: 0032703416     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1053/euhj.1999.1697     Document Type: Article

References (24)

1. Kosinski D, Grubb B, Temesey-Armos P. Pathophysiological aspects of neurocardiogenic syncope: current concepts and new perspectives. PACE. 18:1995;716-724.
2. Benditt DG. Neurally mediated syncopal syndromes: pathophysiological concepts and clinical evaluation. PACE. 20:1997;572-584.
3. Fitzpatrick AP, Sutton R. Tilting towards a diagnosis in recurrent unexplained syncope. Lancet. i:1989;658-660.
4. Grubb BP, Kosinski D. Tilt table testing: concepts and limitations. PACE. 20:1997;781-787.
5. Morillo CA, Leitch JU, Yee R. A placebo controlled trial of intravenous and oral disopyramide for the prevention of neurally mediated syncope induced by head-up tilt. J Am Coll Cardiol. 22:1993;1843-1848.
6. Kapoor WN, Smith M, Miller NL. Upright tilt testing in evaluating syncope: a comprehensive literature review. Am J Med. 97:1994;78-88.
7. Ammirati F, Colivicchi F, Di Battista G. Electroencephalographic correlates of vasovagal syncope induced by head-up tilt testing. Stroke. 29:1998;2347-2351.
8. Fitzpatrick AP, Ahmed R, Williams S. A randomised trial of medical therapy in malignant vasovagal syndrome or neurally medicated bradycardia/hypotension syndrome. Eur J Cardiac Pacing Electrophysiol. 1:1991;198-202.
9. Brignole M, Menozzi C, Gianfranchi L. A controlled trial of acute and long-term medical therapy in tilt-induced neurally mediated syncope. Am J Cardiol. 70:1992;339-342.
10. Petersen MEV, Chamberlain-Weber R, Fitzpatrick AP. Permanent pacing for cardioinhibitory malignant vasovagal syndrome. Br Heart J. 71:1994;274-281.
11. Petersen MEV, Sutton R. Cardiac pacing for vasovagal syncope: a reasonable therapeutic option. PACE. 20:1997;825-826.
12. Sutton R. Is there an effective pharmacological treatment in the prevention of vasovagal syncope. Arch Mal Coeur. 89:1996;25-28.
13. Raviele A, Brignole M, Menozzi C. Development of an implantable drug delivery system for the treatment of vasovagal syncope: a dream or a real prospect. Raviele A. Cardiac Arrhythmias 1997. 1998;422-427 Springer, Berlin.
14. Benditt DG, Lurie KG. Sensor for the early recognition of imminent vasovagal syncope. Raviele A. Cardiac Arrhythmias 1997. 1998;428-434 Springer, Berlin.
15. Brown JH. Atropine, scopolamine and related antimuscarinic drugs. Goodman Gilman A, Rall TW, Nies AS, Taylor P. The pharmacological basis of therapeutics, 8th ed. 1990;150-165 Pergamon Press, New York.
16. Stueven HA, Tonsefeldt DJ, Thompson BM. Atropine in asystole: human studies. Ann Emerg Med. 13:1984;815-821.
17. Lewis T. Vasovagal syncope and the carotid sinus mechanism with comments on Gower's and Nothnagel's syndrome. BMJ. 1:1932;873-876.
18. Quan KJ, Carison MD, Thames MD. Mechanisms of heart rate and arterial blood pressure control: implications for the pathophysiology of neurocardiogenic syncope. PACE. 20:1997;764-774.
19. Murray RH, Shoropshire S. Effects of atropine on circulatory responses to lower body negative pressure and vasodepressor syncope. Aerospace Med. 41:1970;717-740.
20. Goldstein DS, Spanarkel M, Pitterman A. Circulatory control mechanisms in vasodepressor syncope. Am Heart J. 104:1982;1071-1075.
21. Fitzpatrick AP, Theodorakis G, Vardas P, Sutton R. Methodology of head-up tilt testing in patients with unexplained syncope. J Am Coll Cardiol. 17:1991;125-130.
22. Van Lieshout JJ, Wieling W, Karemaker JM. Neural circulatory control in vasovagal syncope. PACE. 20:1997;753-763.
23. Benditt DG, Erickson M, Gammage MD. A synopsis: neurocardiogenic syncope, an international symposium, 1996. PACE. 20:1997;851-860.
24. Ammirati F, Colivicchi F, Toscano S. DDD pacing with rate drop response function versus DDI with rate hysteresis pacing for cardioinhibitory vasovagal syncope. PACE. 20:1998;2178-2181.