Enhanced phenylephrine-induced rhythmic activity in the atherosclerotic mouse aorta via an increase in opening of K(Ca) channels: Relation to K(v) channels and nitric oxide

British Journal of Pharmacology

Volumn 128, Issue 3, 1999, Pages 637-646

  Jiang, Jiahua ^a   Thorén, Peter ^b   Caligiuri, Giuseppina ^a   Hansson, Göran K ^a   Pernow, John ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Aorta; Apolipoprotein E; Calcium channels; Endothelium; Mouse; Nitric oxide; Potassium channels

Indexed keywords

4 AMINOPYRIDINE; 6 ANILINO 5,8 QUINOLINEQUINONE; ACETYLCHOLINE; APOLIPOPROTEIN E; CALCIUM ION; CHARYBDOTOXIN; GUANYLATE CYCLASE INHIBITOR; LOW DENSITY LIPOPROTEIN RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; RYANODINE; TETRYLAMMONIUM;

ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION; VASOMOTOR REFLEX;

4-AMINOPYRIDINE; ACETYLCHOLINE; ANIMALS; AORTA; ARTERIOSCLEROSIS; CALCIUM; CHOLERA TOXIN; ENZYME INHIBITORS; GLYBURIDE; GUANYLATE CYCLASE; INDOMETHACIN; ION CHANNEL GATING; MALE; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE; OUABAIN; PHENYLEPHRINE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RYANODINE; TETRAETHYLAMMONIUM COMPOUNDS;

EID: 0032700214     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702855     Document Type: Article

References (47)

1. + channel by cGMP-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A., 91, 7583-7587.
2. ARNOLD, W.P., MITTEL, C., KATSUKI, S. & MURAD, F. (1977). Nitric oxide activates guanylate cyclase and increases guanosine 3′ : 5′-cyclic monophosphate levels in various tissue preparations. Proc. Natl. Acad. Sci. U.S.A., 74, 3203-3207.
3. BOSSALER, C., HABIB, G.B., YAMOMOTO, H., WILLIAMS, C., WELLS, S. & HENRY, P.D. (1987). Impaired muscarinic endothelial-dependent relaxation and cyclic guanosine 5-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta. J. Clin. Invest., 79, 170-174.
4. BRAYDEN, J.E. & NELSON, M.T. (1992). Regulation of arterial tone by activation of calcium-dependent potassium channels. Science, 256, 532-535.
5. BRESLOW, J.L. (1996). Mouse models of atherosclerosis. Science, 272, 685-688.
6. BUTTERY, L., SPRINGALL, D.R., CHESTER, A.H., EVANS, T.J., STANDFIELD, N., PARUMS, D.V., YACOUB, M.H. & POLAK, J.M. (1996). Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab. Invest., 75, 77-85.
7. + current in arterial membranes from genetically hypertensive rats. Am. J. Physiol., 264, H1337-H1345.
8. FÖRSTERMANN, U., MÜGGE, A., ACHEID, U., HAVERICH, A. & FRÖLICH, J.C. (1988). Selective attenuation of endothelial-mediated vasodilation atherosclerotic human coronary arteries. Circ. Res., 62, 185-190.
9. FREIMAN, P.C., MITCHELL, G.C., HEISTAD, D.D., ARMSTRONG, M.L. & HARRISON, D.G. (1986). Atherosclerosis impairs endothelial-dependent vascular relaxation to acetylcholine and thrombin in primates. Circ. Res., 58, 783-789.
10. GARVEY, E.P., OPLINGER, J.A., FURFINE, E.S., KIFF, R.J., LASZLO, F., WHITTLE, B.J.R. & KNOWLES, R.G. (1997). 1400W is a slow, tight binding, and highly selective inhibitor of inducible nitric-oxide synthase in vitro and vivo. J. Biol. Chem., 272, 4959-4963.
11. GELBAND, C.H. & HUME, J.R. (1992). Ionic currents in single smooth muscle cells from canine renal artery. Circ. Res., 71, 745-758.
12. GIAID, A. & SALEH, D. (1995). Reduced expression of endothelial nitric oxide synthase in the lungs of patients with pulmonary hypertension. N. Engl. J. Med., 333, 214-221.
13. GUSTAFSSON, H., MULVANY, M.J. & NILSSON, H. (1993). Rhythmic contractions of isolated small arteries from rat: influence of the endothelium. Acta. Physiol. Scand., 148, 153-163.
14. HANSSON, G.K., GENG, Y.J., HOLM, J., HÅRDHAMMAR, P., WENNMALM, Å & JENNISCHE, E. (1994). Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J. Exp. Med., 180, 733-738.
15. IBENGWE, J.K. & SUZUKI, H. (1986). Changes in mechanical responses of vascular smooth muscles to acetylcholine, noradrenaline and high-potassium solution in hypercholesterolemic rabbits. Br. J. Pharmacol., 78, 395-402.
16. ISHIBASHI, S., HERZ, J., MAEDA, N., GOLDSTEIN, J.L. & BROWN, M.S. (1994). The two-receptor model of lipoprotein clearance: Tests of the hypothesis in 'knockout' mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc. Natl. Acad. Sci. U.S.A., 93, 10489-10494.
17. JACKSON, W.F., MÜLSCH, A. & BUSSE, R. (1991). Rhythmic smooth muscle activity in hamster aortas is mediated by continuous release of NO from the endothelium. Am. J. Physiol., 260, H248-H253.
18. KAWACHI, Y.,TOMOIKE, H., MARUOKA, Y., KIKUCHI, Y., ARAKI, H., ISHII, Y., TANAKA, K. & NAKAMURA, M. (1984). Selective hypercontraction caused by ergonovine in the canine coronary artery under conditions of induced atherosclerosis. Circulation, 69, 441-450.
19. + channels in rabbit myogenic cerebral arteries. Am. J. Physiol., 269, H348-H355.
20. KOLODGIE, F., VIRMANI, R., RICE, H.E. & MERGNER, W.J. (1990). Vascular reactivity during the progression of atherosclerotic plaque: a study in Watanabe heritable hyperlipidemic rabbits. Circ. Res., 66, 1112-1116.
21. LANGTON, P.D., NELSON, M.T., HUANG, Y. & STANDEN, N.B. (1991). Block of calcium-activated potassium channels in mammalian arterial myocytes by tetraethylammonium ions, Am. J. Physiol., 260, H927-H934.
22. + currents in rabbit coronary myocytes. Am. J. Physiol., 262, C1523-C1537.
23. LEBUFFE, G., BOULLIER, A., TAILLEUX, A., DELFLY, B., DEPUIS, B., FRUCHART, J.C., DUVERGER, N., EMMANUEL, F., DENEFLE, P., VALLET, B. & DURIEZ, P. (1997). Endothelial derived vasorelaxation is impaired in human APO A-I transgenic rabbits. Biochem. Biophys. Res. Comm., 241, 205-211.
24. + channels in aorta of hypertensive rats. Hypertension, 30, 1403-1409.
25. MINOR, R.L., MYERS, P.R., GUERRA, Jr. R., BATES, J.N. & HARRISON, D.G. (1990). Diet-induced atherosclerosis increases the release of nitrogen oxides from rabbit aorta. J. Clin. Invest., 86, 2109-2116.
26. 2+ mobilization causes supersensitivity of contractile response to serotonin in atherosclerotic arteries. Circ. Res., 75, 1096-1102.
27. MORITA, K., IHNKEN, K., BUCKBERG, G.D., SHERMAN, M.P. & IGNARRO, L.J. (1996). Pulmonary vasoconstriction due to impaired nitric oxide production after cardiopulmonary bypass. Annals of Thoracic Surgery, 61, 1775-1780.
28. MÜLSCH, A., BUSSE, R., LIEBAU, S. & FÖRSTERMANN, U. (1988). LY-83583 interferes with the release of endothelium-derived relaxing factor and inhibits soluble guanylate cyclase. J. Pharmacol. Exp. Ther., 247, 283-288.
29. MYERS, J.H., LAMB, F.S. & WEBB, R.C. (1985). Norepinephrine-induced phasic activity in tail arteries from genetically hypertensive rats. Am. J. Physiol., 248, H419-H423.
30. NELSON, M.T. & QUAYLE, J.M. (1995). Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol., 268, C799-C822.
31. NAKASHIMA, Y., PLUMP, A.S., RAINES, E.W., BRESLOW, J.L. & ROSS, R. (1994). ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree. Arterioscler. Thromb., 14, 133-140.
32. PALMER, R.M., ASHTON, D.S. & MONCADA, S. (1988). Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature, 333, 664-666.
33. PIERCY, V. & TAYLOR, S.G. (1998). A comparison of spasmogenic and relaxant responses in aortae from C57/BL/KsJ diabetic mice with those from their non-diabetic litter mates. Pharmacology, 56, 267-275.
34. PLUMP, A.S., SMITH, J.D., HAYEK, T., AALTO, SETÄLÄ, K., WALSH, A., VERSTUYFT, J.G., RUBIN, E.M. & BRESLOW, J.L. (1992). Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell, 71, 343-353.
35. REDDICK, R.L., ZHANG, S.H. & MAEDA, N. (1994). Atherosclerosis in mice lacking apo E: evaluation of lesional development and progression. Arterioscler. Thromb., 14, 141-147.
36. ROSS, G., SCHROEDER, E.S.J. & GINSBURG, R. (1980). Spontaneous phasic activity of isolated human coronary arteries. Cardiovasc. Res., 14, 613-618.
37. STAMLER, J.S., LOH, E., RODDY, M.-A., CURRIE, K.E. & CREAGER, M.A. (1994). Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. Circulation, 89, 2035-2040.
38. STEIN, P.G. & DRISKA, S.P. (1984). Histamine-induced rhythmic contraction of hog carotid artery smooth muscle. Circ. Res., 55, 480-485.
39. TAGAWA, H., TOMOIKE, H., MITSOKA, W., SATOH, S., KUGA, T., SHIMOKAWA, H., NAKAMURA, M. & TAKESHITA, A. (1993). Hyperreactivity of aortic smooth muscle to serotinin is related to the presence of atheroma in Watanabe heritable hyperlipidemic rabbits. Cardiovas. Res., 27, 2164-2169.
40. VOLK, K.A., MATSUDA, J.J. & SHIBADA, E.F. (1991). A voltage-dependent potassium current in rabbit coronary artery smooth muscle cells. J. Physiol. 439, 751-768.
41. i in pulmonary arterial myocytes. Circ. Res., 77, 370-378.
42. + channels. Proc. Natl. Acad. Sci, U.S.A., 93, 10489-10494.
43. ZEIHER, A.M., DREXLER, H., WOLLSCHLÄGER, H. & JUST, H. (1991). Endothelial dysfunction of the coronary microvasculature is associated with coronary blood flow regulation in patients with early atherosclerosis. Circulation, 84, 1984-1992.
44. ZHANG, S.H., REDDICK, R.L., PIEDRAHITA, J.A. & MAEDA, N. (1992). Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science, 258, 468-471.
45. Ca channels antagonizes NO-induced relaxation in pulmonary artery. Am. J. Physiol., 272, H904-H912.
46. ZHOU, X., PAULSSON, G., STEMME, S. & HANSSON, G.K., (1998). Hypercholesterolemia is associated with a Th1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J. Clin. Invest., 101, 1717-1725.
47. ZHOU, X., STEMME, S. & HANSSON, G.K. (1996). Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apo E-deficient mice. Am. J. Pathol., 149, 359-366.