Chemotactic response of periodontal ligament cells decreases with donor age: Association with reduced expression of C-fos

Oral Diseases

Volumn 5, Issue 4, 1999, Pages 337-343

  Asahara, Y ^a,b   Nishimura, F ^a   Arai, H ^a   Kurihara, H ^c   Takashiba, S ^a   Murayama, Y ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Aging; C fos; Cellular senescence; Chemotaxis; Periodontal ligament cells

Indexed keywords

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; FEMALE; GENE EXPRESSION REGULATION; HOST RESISTANCE; HUMAN; HUMAN EXPERIMENT; IMMUNOCYTOCHEMISTRY; MALE; ONCOGENE C FOS; ONCOGENE C MYC; PERIODONTAL LIGAMENT; PRIORITY JOURNAL; SCHOOL CHILD;

EID: 0032699561     PISSN: 1354523X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1601-0825.1999.tb00100.x     Document Type: Article

References (26)

1. Albini A, Pontz, B. Pulz M et al (1988). Decline of fibroblast chemotaxis with age of donor and cell passage number. Coll Relat Res 8: 23-37.
2. Biro S, Fu Y-M, Yu Z-X et al (1993). Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration. Proc Natl Acad Sci USA 90: 654-658.
3. Boyan LA, Bhargava G, Nishimura F et al (1994). Mitogenic and chemotactic responses of human periodontal ligament cells to the different isoforms of platelet-derived growth factor. J Dent Res 73: 1593-1600.
4. Egelberg J (1987). Regeneration and repair of periodontal tissues. J Periodont Res 22: 233-242.
5. Grotendorst GR (1984). Alteration of the chemotactic response of NIH/3T3 cells to PDGF by growth factors, transformation, and tumor promoters. Cell 36: 279-285.
6. Harper JW, Adami GR, Wei N et al (1993). The p21, CDK-interactina protein cip-1 is a potent inhibitor of G1 cyclin-dependent kinase. Cell 70: 993-1006.
7. Hayflick L, Moorhead PS (1961). The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621.
8. Holt JT, Vankat-Gopal T, Moulton AD et al (1986). Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. Proc Natl Acad Sci USA 83: 4794-4798.
9. Hughes FJ, McCulloch CAG (1991). Quantification of chemotactic response of quiescent and proliferating fibroblasts in Boyden chambers by computer-assisted image analysis. J Histochem Cytochem 39: 243-246.
10. Kumazaki T, Rohetorye RS, Robelorye SC et al (1991). Fibronectin expression increases during in vitro cellular senescence. Exp Cell Res 195: 13-19.
11. Martin M, El Nabout R, Lafuma C et al (1990). Fibronectin and collagen sene expression during in vitro ageing of pig skin fibroblasts. Exp Cell Res 191: 8-13.
12. Nishikura K, Murray J (1987). Antisense RNA of proto-oncogene c-fos blocks renewed growth of quiescent 3T3 cells. Mol Cell Biol 7: 639-649.
13. Nishimura F, Terranova V, Foo H et al (1996). Glucose-mediated alteration of cellular function in human periodontal ligament cells. J Dent Res 75: 1664-1671.
14. Nishimura F, Terranova V, Braithwaite M et al (1997). Comparison of in vitro proliterative capacity of human periodontal ligament cells in juvenile and aged donors. Oral Dev 3: 162-166.
15. Noda A, Ning Y, Venable SF et al (1994). Cloning of senescent-cell derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211: 90-98.
16. Owen TA, Cosenza SC, Soprano DR et al (1987). Time of c-fos and c-myc expression in human diploid fibroblasts stimulated to proliferate after prolonged periods of quiescence. J Biol Chem 262: 15111-15117.
17. Persson H, Gray HE, Godeau F (1985). Growth-dependent synthesis of c-myc-encoded proteins: early stimulation by serum factors in synchronized mouse 3T3 cells. Mol Cell Biol 5: 2903-2912.
18. Polyak K, Lee M-H, Erdjument-Bromoge H et al (1994). Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78: 59-66.
19. Riabowol KT, Vosatka RJ, Ziff EB et al (1988). Microinjection of fos-speciric antibodies blocks DNA synthesis in fibroblast cells. Mol Cell Biol 8: 670-676.
20. Riabowol K, Sciff J, Gilman MZ (1992). Transcription factor AP-1 activity is required for the initiation of DNA synthesis and is lost during cellular aging. Proc Natl Acad Sci USA 89: 157-161.
21. Serr CJ (1993). Mammalian G1 cyclins. Cell 73: 1059-1065.
22. Serrano M, Hannon GJ, Beach D (1993). A new regulatory motif in cell-cycle control causing specific inhibition of cyclin/CDK 4. Nature 366: 704-707.
23. Schiffman E, Gallin JI (1979). Biochemistry of phagocyte chemotaxis. In: Horecker BL, Stadtman ER, eds. Current topics in cell regulation, Vol. 15. Academic Press: New York, pp 203-216.
24. Stein GH, Beeson M, Gordon L (1990). Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts. Science 249: 666-669.
25. Toyoshima H, Hunter T (1994). p27, a novel inhibitor of G1 cyclin-CDK protein kinase activity, is related to p21. Cell 78: 67-74.
26. Wang E (1995). Senescent human fibroblasts resist programmed cell death, and failure to suppress bc12 is involved. Cancer Res 55: 2284-2292.