Lack of negative influence on the cellular transcription factors NF-κB and AP-1 by the Nef protein of human immunodeficiency virus type 1

Journal of General Virology

Volumn 80, Issue 11, 1999, Pages 2951-2956

  Yoon, Keejung ^a   Kim, Sunyoung ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHYTOHEMAGGLUTININ; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL LINE; DOWN REGULATION; ELECTROPHORETIC MOBILITY; FLUORESCENCE ACTIVATED CELL SORTER; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; T LYMPHOCYTE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0032698489     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-80-11-2951     Document Type: Article

References (30)

1. Alexander, L., Du, Z., Rosenzweig, M., Jung, J. U. & Desrosiers, R. C. (1997). A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation. Journal of Virology 71, 6094-6099.
2. Allan, J. S., Coligan, J. E., Lee, T. H., McLane, M. F., Kanki, P. J., Groopman, J. E. & Essex, M. (1985). A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients. Science 230, 810-813.
3. Bandres, J. C. & Ratner, L. (1994). Human immunodeficiency virus type 1 Nef protein down-regulates transcription factors NF-kappa B and AP-1 in human T cells in vitro after T-cell receptor stimulation. Journal of Virology 68, 3243-3249.
4. Beaver, B. & Wong-Staal, F. (1989). Structure of simian immunodeficiency virus regulatory gene. Proceedings of the National Academy of Sciences, USA 86, 4813-4817.
5. Brigino, E., Haraguchi, S., Koutsonikolis, A., Cianciolo, G. J., Owens, U., Good, R. A. & Day, N. K. (1997). Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway. Proceedings of the National Academy of Sciences, USA 94, 3178-3182.
6. Byun, J., Kim, S. H., Kim, J. M., Yu, S. S., Robbins, P. D., Yim, J. & Kim, S. (1996). Analysis of the relative level of gene expression from different retroviral vectors used for gene therapy. Gene Therapy 9, 780-788.
7. Chowers, M. Y., Spina, C. A., Kwoh, T. J., Fitch, N. J. S., Richman, D. D. & Guatelli, J. C. (1994). Optimal infectivity in vitro of human immunodeficiency virus type 1 required an intact nef gene. Journal of Virology 68, 2906-2914.
8. Deacon, N. J., Tsykin, A., Solomon, A., Smith, K., Ludford-Menting, M., Hooker, D. J., McPhee, D. A., Greenway, A. L., Ellett, A., Chatfield, C., Lawson, V. A., Crowe, S., Maerz, A., Sonza, S., Learmont, J., Sullivan, J. S., Cunningham, A., Dwyer, D., Dowton, D. & Mills, J. (1995). Genomic structure of an attenuated quasispecies of HIV-1 from a cohort of a blood transfusion donor and recipients. Science 270, 988-991.
9. de Ronde, A., Klaver, B., Keulen, W., Smith, L. & Goudsmit, J. (1992). Natural HIV-1 Nef accelerates virus replication in primary human lymphocytes. Virology 187, 391-395.
10. Dignam, J. D., Lebovitz, R. M. & Roeder, R. G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Research 11, 1475-1489.
11. Finer, M. H., Dull, T. J., Qin, L., Farson, D. & Roberts, M. R. (1994). kat: a high-efficiency retroviral transduction system for primary human T lymphocytes. Blood 83, 43-50.
12. Franchini, G. & Robert-Guroff, M. (1986). Cytoplasmic localisation of the HTLV III 3′ orf in cultured T cells. Virology 155, 593-599.
13. Greene, W. C. (1991). The molecular biology of human immunodeficiency virus type 1 infection. New England Journal of Medicine 324, 308-317.
14. Greenway, A., Azad, A. & McPhee, D. (1995). Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. Journal of Virology 69, 1842-1850.
15. Grosschedl, R. & Baltimore, D. (1985). Cell-type specificity of immunoglobulin gene expression is regulated by at least three DNA sequence elements. Cell 41, 885-897.
16. Kaminchik, J., Bashan, N., Itach, A., N, S., Gorecki, M. & Panet, A. (1991). Genetic characterization of human immunodeficiency virus type 1 nef gene products translated in vitro and expressed in mammalian cells. Journal of Virology 65, 583-588.
17. Kekule, A. S., Lauer, U., Weiss, L., Luber, B. & Hofschneider, P. H. (1993). Negative regulation of human c-fos expression by the retinoblastoma gene product. Nature 346, 668-671.
18. Kestler, H. W., Ringler, D. J., Mori, K., Panicali, D. L., Sehgal, P. K., Daniel, M. D. & Desrosiers, R. C. (1991). Importance of the nef gene for maintenance of high virus loads and for the development of AIDS. Cell 65, 651-662.
19. Kim, S., Ikeuchi, K., Byrn, R., Groopman, J. & Baltimore, D. (1989). Lack of negative influence on viral growth by the nef gene of human immunodeficiency virus type 1. Proceedings of the National Academy of Sciences, USA 86, 9544-9588.
20. Kim, S., Yu, S. S. & Kim, V. N. (1996). Essential role of NF-κB in transactivation of the human immunodeficiency virus long terminal repeat by the human cytomegalovirus IE1 protein. Journal of General Virology 77, 83-91.
21. Kim, S. H., Yu, S. S., Park, J. S., Robbins, P. D., An, C. S. & Kim, S. (1998). Construction of retroviral vectors with improved safety, gene expression, and versatility. Journal of Virology 72, 994-1004.
22. Kirchhoff, F., Greenough, T. C., Brettler, D. B., Sullivan, J. L. & Desrosiers, R. C. (1995). Absence of intact nef sequences in a long-term survivor with non-progressive HIV-1 infection. New England Journal of Medicine 332, 228-232.
23. Miller, M. D., Warmerdam, M. T., Gaston, I., Green, W. C. & Feinberg, M. B. (1994). The human immunodeficiency virus type 1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. Journal of Experimental Medicine 179, 101-113.
24. Nabel, G. & Baltimore, D. (1987). An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature 326, 711-713.
25. Niederman, T. M., Garcia, J. V., Hastings, W. R., Luria, S. & Ratner, L. (1992). Human immunodeficiency virus type 1 Nef protein inhibits NF-kappa B induction in human T cells. Journal of Virology 66, 6213-6219.
26. Page, K. A., van Schooten, W. C. & Feinberg, M. B. (1997). Human immunodeficiency virus type 1 Nef does not alter T-cell sensitivity to antigen-specific stimulation. Journal of Virology 71, 3776-3787.
27. Robbins, P. D., Horowitz, J. M. & Mulligan, R. C. (1990). Negative regulation of human c-fos expression by the retinoblastoma gene product. Nature 346, 668-671.
28. Schwartz, O., Arenzana-Seisdedos, F., Heard, J. M. & Danos, O. (1992). Activation pathways and human immunodeficiency virus type 1 replication are not altered in CD4 + T cells expressing the nef protein. AIDS Research and Human Retroviruses 8, 545-551.
29. Shibata, R., Miura, T., Hayami, M., Ogawa, K., Sakai, H., Kiyomasu, T., Ishimoto, A. & Adachi, A. (1990). Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIVAGM. Journal of Virology 64, 742-747.
30. Spina, C. A., Kwoh, T. J., Chowers, M. Y., Guatelli, J. C. & Richman, D. D. (1994). The importance of Nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes. Journal of Experimental Medicine 179, 115-123.