Major metabolites of substance P degraded by spinal synaptic membranes antagonize the behavioral response to substance P in rats

Journal of Pharmaceutical Sciences

Volumn 88, Issue 11, 1999, Pages 1127-1132

  Sakurada, Chikai ^a   Watanabe, Chizuko ^b   Sakurada, Shinobu ^b   Tan No, Koichi ^b   Sakurada, Tsukasa ^a  

^a DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^b TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; CHELATING AGENT; MEMBRANE METALLOENDOPEPTIDASE; PHENYLALANINE; PHOSPHORAMIDON; PROTEINASE INHIBITOR; SUBSTANCE P; SUBSTANCE P DERIVATIVE; SUBSTANCE P [1-4]; SUBSTANCE P [1-7]; THIORPHAN;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BITE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; INTRATHECAL DRUG ADMINISTRATION; LICKING; MALE; NONHUMAN; PROTEIN DEGRADATION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCRATCHING; SPINAL CORD; SYNAPTIC MEMBRANE;

EID: 0032697876     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js990149c     Document Type: Article

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