Staged high-dose epinephrine clysis is safe and effective in extensive tangential burn excisions in children

Burns

Volumn 25, Issue 8, 1999, Pages 745-748

  Sheridan, R L ^a,b,d   Szyfelbein, S K ^a,c,d  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

^b Division of Trauma Emergency Surgery and Surgical Critical Care   (United States)

^c Massachusetts General Hosptial ^*  (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Blood loss; Burn surgery; Wound excisions

Indexed keywords

ADRENALIN;

ADOLESCENT; ARTICLE; BLEEDING; BLOOD TRANSFUSION; BODY SURFACE; BURN; BURN EXCISION; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; INFANT; MALE; SUBCUTANEOUS DRUG ADMINISTRATION; VASOCONSTRICTION;

ADOLESCENT; BLOOD LOSS, SURGICAL; BLOOD VOLUME; BURNS; CHILD; CHILD, PRESCHOOL; ENEMA; EPINEPHRINE; HEMATOCRIT; HEMOSTATIC TECHNIQUES; HUMANS; INFANT; PROSPECTIVE STUDIES; SAFETY; SKIN TRANSPLANTATION; TREATMENT OUTCOME; VASOCONSTRICTOR AGENTS; WOUND HEALING;

EID: 0032697344     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-4179(99)00088-1     Document Type: Article

References (21)

1. Sheridan R.L., Tompkins R.G., Burke J.F. Management of burn wounds with prompt excision and immediate closure. J. Intensive Care Med. 9:1994;6-19.
2. Tompkins R.G., Remensnyder J.P., Burke J.F., et al. Significant reductions in mortality for children with burn injuries through the use of prompt eschar excision. Ann. Surg. 208:1988;577-585.
3. Desai M.H., Herndon D.N., Broemeling L., Barrow R.E., Nichols R.J. Jr, Rutan R.L. Early burn wound excision significantly reduces blood loss. Ann. Surg. 211:1990;753-759.
4. Morris J.A. Jr, Wilcox T.R., Reed G.W., et al. Safety of the blood supply. Surrogate testing and transmission of hepatitis C in patients after massive transfusion. Ann. Surg. 219:1994;517-525.
5. Robinson N.B., Heimbach D.M., Reynolds L.O., et al. Ventilation and perfusion alterations following homologous blood transfusion. Surgery. 92:1982;183-191.
6. Graves T.A., Cioffi W.G., Mason A.D. Jr, McManus W.F., Pruitt B.A. Jr. Relationship of transfusion and infection in a burn population. J. Trauma. 29:1989;948-952.
7. Mann R., Heimbach D.M., Engrav L.H., Foy H. Changes in transfusion practices in burn patients. J. Trauma. 37:1994;220-222.
8. Sittig K.M., Deitch E.A. Blood transfusions: for the thermally injured or for the doctor? J. Trauma. 36:1994;369-372.
9. Miki C., Iriyama K., Gunson B.K., Mayer A.D., Buckels J.A., McMaster P. Influence of intraoperative blood loss on plasma levels of cytokines and endotoxin and subsequent graft liver function. Arch. Surg. 132:1997;136-141.
10. Roberts A.H. The effect of topical epinephrine on blood loss following tangential excision of burn wounds. Plast. Reconstr. Surg. 74:1984;450-451.
11. Snelling C.F., Shaw K. The effect of topical epinephrine hydrochloride in saline on blood loss following tangential excision of burn wounds. Plast. Reconstr. Surg. 72:1983;830-836.
12. Siegel R.J., Vistnes L.M., Iverson R.E. Effective hemostasis with less epinephrine. An experimental and clinical study. Plast. Reconstr. Surg. 51:1973;129-133.
13. Marano M.A., O'Sullivan G., Madden M., Finkelstein J., Goodwin C.W. Tourniquet technique for reduced blood loss and wound assessment during excisions of burn wounds of the extremity. Surg. Gynecol. Obstetr. 171:1990;249-250.
14. Rosenberg J.L., Zawacki B.E. Reduction of blood loss using tourniquets and 'compression' dressings in excising limb burns. J. Trauma. 26:1986;47-50.
15. Henley M., Tomlinson P., Bailie F.B., Obeid E.M. Acute haemodilution in surgery for burns: a preliminary report. Br. J. Surg. 80:1993;1294-1295.
16. Szyfelbein S.K., Ryan J.F. Use of controlled hypotension for primary surgical excision in an extensively burned child. Anesthesiology. 41:1974;501-503.
17. Janezic T., Prezelj B., Brcic A., Arnez Z., Zaletelj-Kragelj L. Intraoperative blood loss after tangential excision of burn wounds treated by subeschar infiltration of epinephrine. Scand. J. Plast. Reconstr. Surg. Hand Surg. 31:1997;245-250.
18. Glatter R., Bua D., Nishioka N., Shomaker K., Sheridan R. Carbon dioxide laser ablation with immediate autografting in a full thickness porcine burn model. Ann. Surg. 228:(2):1998;257-265.
19. Budny P.G., Regan P.J., Roberts A.H. The estimation of blood loss during burns surgery. Burns. 19:1993;134-137.
20. Moran K.T., O'Reilly T.J., Furman W., Munster A.M. A new algorithm for calculation of blood loss in excisional burn surgery. Am. Surg. 54:1988;207-208.
21. Housinger T.A., Lang D., Warden G.D. A prospective study of blood loss with excisional therapy in pediatric burn patients. J. Trauma. 34:1993;262-263.