Little benefit from mild hypothermia therapy for severely head injured patients with low intracranial pressure

Journal of Neurosurgery

Volumn 91, Issue 2, 1999, Pages 185-191

  Shiozaki, Tadahiko ^a   Kato, Amami ^b   Taneda, Mamoru ^b   Hayakata, Toshiaki ^b   Hashiguchi, Naoyuki ^b   Tanaka, Hiroshi ^b   Shimazu, Takeshi ^b   Sugimoto, Hisashi ^b  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b NONE

Author keywords

Intracranial pressure; Mild hypothermia; Normothermia; Severe head injury

Indexed keywords

ASPARTIC ACID; BARBITURIC ACID DERIVATIVE; GLUTAMIC ACID; GLYCINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; AMINO ACID BRAIN LEVEL; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETES INSIPIDUS; DISEASE ASSOCIATION; DISEASE COURSE; DRUG MEGADOSE; FEMALE; HEAD INJURY; HUMAN; HYPERNATREMIA; INDUCED HYPOTHERMIA; INTRACRANIAL PRESSURE; MALE; PNEUMONIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0032696982     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1999.91.2.0185     Document Type: Article

References (26)

1. Baker AJ, Moulton RJ, MacMillan VH, et al: Excitatory amino acids in cerebrospinal fluid following traumatic brain injury in humans. J Neurosurg 79:369-372, 1993
2. Bell MJ, Kochanek PM, Doughty LA, et al: Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children. J Neurotrauma 14:451-457, 1997
3. Bullock R, Zauner A, Woodward JJ, et al: Factors affecting excitatory amino acid release following severe human head injury. J Neurosurg 89:507-518, 1998
4. Busto R, Globus MYT, Dietrich WD, et al: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 20:904-910, 1989
5. Clifton GL, Allen S, Barrodale P, et al: A phase II study of moderate hypothermia in severe brain injury. J Neurotrauma 10: 263-273, 1993
6. Dietrich WD, Busto R, Halley M, et al: The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. J Neuropathol Exp Neurol 49:486-497, 1990
7. Faden AI, Demediuk P, Panter SS, et al: The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244:798-800, 1989
8. Jennett B, Bond M: Assessment of outcome after severe brain damage. A practical scale. Lancet 1:480-484, 1975
9. Katayama Y, Becker DP, Tamura T, et al: Massive increases in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. J Neurosurg 73: 889-900, 1990
10. Kurz A, Sessler DI, Lenhardt R, et al: Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. N Engl J Med 334:1209-1215, 1996
11. Lipton SA, Rosenberg PA: Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 330: 613-622, 1994
12. Marion DW, Obrist WD, Carlier PM, et al: The use of moderate therapeutic hypothermia for patients with severe head injuries: a preliminary report. J Neurosurg 79:354-362, 1993
13. Marion DW, Penrod LE, Kelsey SF, et al: Treatment of traumatic brain injury with moderate hypothermia. N Engl J Med 336:540-546, 1997
14. Metz C, Holzschuh M, Bein T, et al: Moderate hypothermia in patients with severe head injury: cerebral and extracerebral effects. J Neurosurg 85:533-541, 1996
15. Miller JD: Disorders of cerebral blood flow and intracranial pressure after head injury. Clin Neurosurg 29:162-173, 1982
16. Ogura H, Tanaka H, Koh T, et al: Priming, second-hit priming, and apoptosis in leukocytes from trauma patients. J Trauma 46:774-783, 1999
17. Ott L, McClain CJ, Gillespie M, et al: Cytokines and metabolic dysfunction after severe head injury. J Neurotrauma 11: 447-472, 1994
18. Saul TG: Is ICP monitoring worthwhile? Clin Neurosurg 34: 560-571, 1987
19. Seelig JM, Becker DP, Miller JD, et al: Traumatic acute subdural hematoma. Major mortality reduction in comatose patients treated within four hours. N Engl J Med 304:1511-1518, 1981
20. Segar WE, Riley PA Jr, Barila TG, et al: Urinary composition during hypothermia. Am J Physiol 185:528-532, 1956
21. Shiozaki T, Sugimoto H, Taneda M, et al: Effect of mild hypothermia on uncontrollable intracranial hypertension after severe head injury. J Neurosurg 79:363-368, 1993
22. Shiozaki T, Sugimoto H, Taneda M, et al: Selection of severely head injured patients for mild hypothermia therapy. J Neurosurg 89:206-211, 1998
23. Smith DH, Okiyama K, Thomas M, et al: An NMDA receptor-associated glycine site antagonist attenuates memory loss after experimental brain injury. Soc Neurosci 16:779, 1990 (Abstract)
24. Smith SL, Hall ED: Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat. J Neurotrauma 13:1-9, 1996
25. Teasdale G, Jennett B: Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81-84, 1974
26. Wilberger JE, Harris M, Diamond DL: Acute subdural hematoma: morbidity, mortality, and operative timing. J Neurosurg 74:212-218, 1991