메뉴 건너뛰기




Volumn 81, Issue 5, 1999, Pages 790-795

Suppression of the c-erbB-2 gene product decreases transformation abilities but not the proliferation and secretion of proteases of SK-OV-3 ovarian cancer cells

Author keywords

c erbB 2 oncogene; Cell transformation; Ovarian cancer; Proteases; Single chain antibody

Indexed keywords

ANTIBODY; MATRIX METALLOPROTEINASE; ONCOPROTEIN; UROKINASE;

EID: 0032696701     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6690765     Document Type: Article
Times cited : (7)

References (23)
  • 1
    • 0028823802 scopus 로고
    • Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2
    • Beerli RR, Graus-Porta D, Woods-Cook K, Chen X, Yarden Y and Hynes NE (1995) Neu differentiation factor activation of ErbB-3 and ErbB-4 is cell specific and displays a differential requirement for ErbB-2. Mol Cell Biol 15: 6496-6505
    • (1995) Mol Cell Biol , vol.15 , pp. 6496-6505
    • Beerli, R.R.1    Graus-Porta, D.2    Woods-Cook, K.3    Chen, X.4    Yarden, Y.5    Hynes, N.E.6
  • 3
    • 0028948002 scopus 로고
    • The significance of urokinase-type plasminogen activator, its inhibitors, and its receptor in ascites of patients with epithelial ovarian cancer
    • Chambers SK, Gertz RE, Ivins CM and Kacinski BM (1995) The significance of urokinase-type plasminogen activator, its inhibitors, and its receptor in ascites of patients with epithelial ovarian cancer. Cancer 75: 1627-1633
    • (1995) Cancer , vol.75 , pp. 1627-1633
    • Chambers, S.K.1    Gertz, R.E.2    Ivins, C.M.3    Kacinski, B.M.4
  • 4
    • 0028823836 scopus 로고
    • Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
    • Deshane J, Cabrera G, Grim J, Siegal GP, Pike J, Alvarez RD and Curiel DT (1995) Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody. Gynecol Oncol 59: 8-14
    • (1995) Gynecol Oncol , vol.59 , pp. 8-14
    • Deshane, J.1    Cabrera, G.2    Grim, J.3    Siegal, G.P.4    Pike, J.5    Alvarez, R.D.6    Curiel, D.T.7
  • 7
    • 0029078999 scopus 로고
    • A microplate assay for quantitation of anchorage-independent growth of transformed cells
    • Fukazawa H, Mizuno S and Uchara Y (1995) A microplate assay for quantitation of anchorage-independent growth of transformed cells. Anal Biochem 228: 83-90
    • (1995) Anal Biochem , vol.228 , pp. 83-90
    • Fukazawa, H.1    Mizuno, S.2    Uchara, Y.3
  • 8
    • 0032581532 scopus 로고    scopus 로고
    • Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation
    • Giani C, Casalini P, Pupa SM, De Vecchi R, Ardini E, Colnaghi MI, Giordano A and Menard S (1998) Increased expression of c-erbB-2 in hormone-dependent breast cancer cells inhibits cell growth and induces differentiation. Oncogene 17: 425-432
    • (1998) Oncogene , vol.17 , pp. 425-432
    • Giani, C.1    Casalini, P.2    Pupa, S.M.3    De Vecchi, R.4    Ardini, E.5    Colnaghi, M.I.6    Giordano, A.7    Menard, S.8
  • 9
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of ErbB-2 impairs neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta D, Beerli RR and Hynes NE (1995) Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling. Mol Cell Biol 15: 1182-1191
    • (1995) Mol Cell Biol , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.R.2    Hynes, N.E.3
  • 10
    • 0030944455 scopus 로고    scopus 로고
    • ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
    • Graus-Porta D, Beerli RR, Daly JM and Hynes NE (1997) ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16: 1647-1655
    • (1997) EMBO J , vol.16 , pp. 1647-1655
    • Graus-Porta, D.1    Beerli, R.R.2    Daly, J.M.3    Hynes, N.E.4
  • 11
    • 0029148284 scopus 로고
    • Up-regulation of urokinase-type plasminogen activator by expression by the HER2/neu proto-oncogene
    • Gum R, Wang SW, Lengyel E, Yu D, Hung M-C, Juarez J and Boyd D (1995) Up-regulation of urokinase-type plasminogen activator by expression by the HER2/neu proto-oncogene. Anticancer Res 15: 1167-1172
    • (1995) Anticancer Res , vol.15 , pp. 1167-1172
    • Gum, R.1    Wang, S.W.2    Lengyel, E.3    Yu, D.4    Hung, M.-C.5    Juarez, J.6    Boyd, D.7
  • 13
    • 0024326947 scopus 로고
    • Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumors
    • Kraus MH, Issing W, Miki T, Popescu NC and Aaronson SA (1989) Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci USA 86: 9193-9197
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9193-9197
    • Kraus, M.H.1    Issing, W.2    Miki, T.3    Popescu, N.C.4    Aaronson, S.A.5
  • 14
    • 0028082242 scopus 로고
    • Overexpression of the oncogene c-erbB2 in primary ovarian cancer: Evaluation of the prognostic value in n Cox proportional hazards multiple regression
    • Meden H, Mars D, Rath W, Kron M, Faltahi-Meibodi A, Hinney B, Kuhn W and Schauer A (1994) Overexpression of the oncogene c-erbB2 in primary ovarian cancer: evaluation of the prognostic value in n Cox proportional hazards multiple regression. Int J Gynecol Pathol 13: 45-53
    • (1994) Int J Gynecol Pathol , vol.13 , pp. 45-53
    • Meden, H.1    Mars, D.2    Rath, W.3    Kron, M.4    Faltahi-Meibodi, A.5    Hinney, B.6    Kuhn, W.7    Schauer, A.8
  • 15
    • 0027262985 scopus 로고
    • Biological consequences of overexpression of a transfected c-erbB-2 gene in immortalized human bronchial epithelial cells
    • Noguchi M, Murakami M, Bennett W, Lupu R, Hui F, Harris CC and Gerwin BI. (1993) Biological consequences of overexpression of a transfected c-erbB-2 gene in immortalized human bronchial epithelial cells. Cancer Res 53: 2035-2043
    • (1993) Cancer Res , vol.53 , pp. 2035-2043
    • Noguchi, M.1    Murakami, M.2    Bennett, W.3    Lupu, R.4    Hui, F.5    Harris, C.C.6    Gerwin, B.I.7
  • 16
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML and Baltimore D (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 90: 8392-8396
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 18
    • 0029086675 scopus 로고
    • Primary tumor and metastasis in ovarian cancer differ in their content of urokinase-type plasminogen activator, its receptor, and inhibitors types 1 and 2
    • Schmalfeldt B, Kuhn W, Reuning U, Pache L, Dettmar P, Schmitt M, Jänicke F, Höfler H and Graeff H (1995) Primary tumor and metastasis in ovarian cancer differ in their content of urokinase-type plasminogen activator, its receptor, and inhibitors types 1 and 2. Cancer Res 55: 3958-3963
    • (1995) Cancer Res , vol.55 , pp. 3958-3963
    • Schmalfeldt, B.1    Kuhn, W.2    Reuning, U.3    Pache, L.4    Dettmar, P.5    Schmitt, M.6    Jänicke, F.7    Höfler, H.8    Graeff, H.9
  • 19
    • 0028827415 scopus 로고
    • Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form
    • Tamakoshi K, Kikkawa F, Nawa A, Ishikawa H, Mizuno K, Tamakoshi A, Yamagata S, Suganuma N and Tomoda Y (1995) Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form. Cancer 76: 2565-2571
    • (1995) Cancer , vol.76 , pp. 2565-2571
    • Tamakoshi, K.1    Kikkawa, F.2    Nawa, A.3    Ishikawa, H.4    Mizuno, K.5    Tamakoshi, A.6    Yamagata, S.7    Suganuma, N.8    Tomoda, Y.9
  • 20
    • 0030968290 scopus 로고    scopus 로고
    • Overexpression of the c-erbH-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities
    • Tan M, Yao J and Yu D (1997) Overexpression of the c-erbH-2 gene enhanced intrinsic metastasis potential in human breast cancer cells without increasing their transformation abilities. Cancer Res 57: 1199-1205
    • (1997) Cancer Res , vol.57 , pp. 1199-1205
    • Tan, M.1    Yao, J.2    Yu, D.3
  • 22
    • 0025940263 scopus 로고
    • Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells
    • Yu DH and Hung M-C (1991) Expression of activated rat neu oncogene is sufficient to induce experimental metastasis in 3T3 cells. Oncogene 6: 1991-1996
    • (1991) Oncogene , vol.6 , pp. 1991-1996
    • Yu, D.H.1    Hung, M.-C.2
  • 23
    • 0027409399 scopus 로고
    • Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A
    • Yu D, Wolf JK, Scanlon M, Price JE and Hung M-C (1993) Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A. Cancer Res 53: 891-898
    • (1993) Cancer Res , vol.53 , pp. 891-898
    • Yu, D.1    Wolf, J.K.2    Scanlon, M.3    Price, J.E.4    Hung, M.-C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.