Co, fe and ga chelates for cell labelling a potential use in pet imaging?

Nuclear Medicine Communications

Volumn 20, Issue 11, 1999, Pages 1017-1022

  Ellis, Beverley L ^a   Sharma, H L ^b  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COBALT; GALLIUM; IRON;

ARTICLE; CELL FREE SYSTEM; CELL KINETICS; CELL VIABILITY; COMPLEX FORMATION; DIAGNOSTIC IMAGING; ISOTOPE LABELING; LABELING INDEX; LEUKOCYTE; LIGAND BINDING; POSITRON EMISSION TOMOGRAPHY; TARGET CELL;

CELL SURVIVAL; CHELATING AGENTS; COBALT; COBALT RADIOISOTOPES; ERYTHROCYTES; GALLIUM; GALLIUM RADIOISOTOPES; HUMANS; HYDROGEN PEROXIDE; IRON; IRON RADIOISOTOPES; ISOTOPE LABELING; LEUKOCYTES; OXIDANTS; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0032694661     PISSN: 01433636     EISSN: 14735628     Source Type: Journal    
DOI: 10.1080/00006231-199911000-00006     Document Type: Article

References (16)

1. Thakur ML, Lavender JP, Arnot RN, Silvester DJ, Segal AW. Indium-lll-labeled autologous leukocytes in man. J Nucl Med 1977; 18: 1012-1019.
2. Danpure HJ, Osman S, Brady F. The labelling of blood cells in plasma with lnIn. Br J Radiol 1982; 55: 247-249.
3. Thakur ML, McKenney SL, Park CH. Evaluation of indium-lll-2-mercaptopyridine-N-oxide for labeling leukocytes in plasma: A kit preparation. J Nucl Med 1985; 26: 518-523.
4. Thakur ML, Segal AW, Louis L, Welch MJ, Hopkins J, Peters TJ. Indium-lll-labeled cellular blood components: Mechanism of labeling and intracellular location in human neutrophils. J Nucl Med 1977; 18: 1020-1024.
5. Sharma HL, Cowan RA, Murby B et al. Treatment of lymphoid cell malignancy with In-114m labelled autologous lymphocytes. Anticancer Res 1997; 17: 1815-1821.
6. Goodwin DA, Lang EV, Atwood JE et al. Viability and bio-distribution of 68Ga MPO-labelled human platelets. Nucl Med Commun 1993; 14: 1023-1029.
7. Welch MJ, Thakur ML, Coleman RE, Patel M, Siegel BA, Ter-Pogossian MM. Gallium-68 labeled red cells and platelets: New agents for positron tomography. J Nucl Med 1977; 18: 558-562.
8. Yano Y, Budinger TF, Ebbe SN et al. Gallium-68 lipophilic complexes for labeling platelets. J Nucl Med 1985; 26: 1429-1437.
9. Sharma H, Zweit J, Smith AM, Downey S. Production of cobalt-55, a short-lived, positron emitting radiolabel for bleomycin. Appl Radiat Isot 1986; 37: 105-109.
10. Zweit J, Downey S, Sharma H. A method for the production of iron-52 with a very low iron-55 contamination. Appl Radiat Isot 1988; 39: 1197-1201.
11. Zweit J, Sharma H, Downey S. Production of gallium-66, a short-lived, positron emitting radionuclide. Appl Radiat Isot 1987; 38: 499-501.
12. Hollingshead RGW. Oxine and its derivatives. London: Butter worths, 1954.
13. Eaton SS, Hutchinson JR, Holm RH, Muetterties EL. Intra-molecular rearrangement reactions of tris-chelate complexes. III. Analysis of the rearrangements of tris(a-isopropenyl-and a-isotropolonato) aluminum(III) and-cobalt(III). Examples of stereochemically nonrigid aluminum(III) and cobalt(III) complexes. J Am Chem Soc 1972; 94: 6411-6426.
14. Thakur ML, Zoghbi SS. Structure-activity relationship in cell labeling. In: Subramanian G, Rhodes BA, Cooper JF, Sodd VJ, eds. Radiopharmaceuticals. New York: Society of Nuclear Medicine, 1975: 505-517.
15. Ellis BL, Duhme AK, Hider RC, Hossain MB, Rizvi S, van der Helm D. Synthesis, physiochemical properties and biological evaluation of hydroxypyranones and hydroxypyr-idinones: Novel bidentate ligands for cell labeling. J Med Chem 1996; 39: 3659-3670.
16. Karanikas G, Rodrigues M, Granegger S, Sinzinger H. Are 68Ga-chelates useful for positron emission tomographic (PET) platelet imaging? Nucl Med Commun 1997; 18: 488.