Soluble platelet selectin (sP-selectin) and soluble vascular cell adhesion molecule-1 (sVCAM-1) decrease during therapy with benznidazole in children with indeterminate form of Chagas' disease

Clinical and Experimental Immunology

Volumn 118, Issue 3, 1999, Pages 423-427

  Laucella, Susana ^a,c   Segura, E L ^a   Riarte, A ^a   Sosa, Estani S ^b  

^a Administracion Natl de I   (Argentina)

^b Min de Salud y Accion Social   (Argentina)

^c NONE   (Argentina)

Author keywords

Benznidazole; Chagas' disease; sP selectin; sVCAM 1; Trypanosoma cruzi

Indexed keywords

BENZNIDAZOLE; SELECTIN; VASCULAR CELL ADHESION MOLECULE 1;

ANTIBIOTIC THERAPY; ARTICLE; CHAGAS DISEASE; CHEMOTHERAPY; CHILD; CONTROLLED STUDY; CORRELATION FUNCTION; DISEASE CLASSIFICATION; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; MAJOR CLINICAL STUDY; PARASITE CONTROL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE ASSAY; SCHOOL CHILD; TRYPANOSOMA CRUZI;

CHAGAS DISEASE; CHILD; DOUBLE-BLIND METHOD; HUMANS; NITROIMIDAZOLES; P-SELECTIN; REGRESSION ANALYSIS; TRYPANOCIDAL AGENTS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0032693540     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.01070.x     Document Type: Article

References (40)

1. 1 Moncayo A. Chagas' disease. Geneva: World Health Organization. Tropical Disease Research, Eleventh Program Report, 1993:67-75.
2. 2 Yoshida N, Schenkman S. American trypanosomiasis. Curr Opin Infect Dis 1997; 10:351-6.
3. 3 Weller A, Iscnmann S, Vestweber D. Cloning of the mouse endothelial selectins. J Biol Chem 1992; 25:15176-83.
4. 4 Yao L, Pan J, Setiadi H, Patel KM, McEver RP. Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells. J Exp Med 1996; 184:81-92.
5. 5 Khew-Goodall Y, Butcher CM, Litwin MS et al. Chronic expression of P-selectin on endothelial cells stimulated by the T-cell cytokine, interleukin 3. Blood 1996; 87:1432-8.
6. 6 Cybulsky MI, Fries JWU, Williams AJ et al. Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM-1 gene. Proc Natl Acad Sci USA 1991; 8:7959-863.
7. 7 Foster CA. VCAM-1/a4 integrin adhesion pathway: therapeutic target for allergic inflammatory disorders. J Allergy Clin Immunol 1996; 98:S270-7.
8. 8 Geuring AJH, Hemingway I, Pigott R, Hughes J, Rees AJ, Cashman SJ. Soluble forms of vascular adhesion molecules, E-selectin, ICAM-1, and VCAM-1: pathological significance. Ann N Y Acad Sci 1992; 667:324-31.
9. 9 Sherburne R, Taylor DE. Helicobacterpylori express a complex surface carbohydrate, Lewis X. Infect Immun 1995; 63:4564-8.
10. 10 Rathore A, Sacristán C, De Ricklan, Flores Villanueva PO, Stadecker MJ. In situ analysis of B7-2 costimulalory, major histocompatibilily complex class II, and adhesion molecule expression in schistosomal egg granulomas. Am J Pathol 1996; 149:187-94.
11. 11 Jakobsen P, Morris-Jones S, Ronn A, Hviid L, Theander T, Elhassan I, Bygbjerg I, Greenwood B. Increased plasma concentrations of s-ICAM-1, s-VCAM-1 and s-ELAM-1 in patients with Plasmodium falciparum or P. vivax malaria in association with disease severity. Immunol 1994; 83:665-9.
12. 12 D'Avila Reis D, Jones MJ, Tostes S et al. Expression of major histocompatibilily complex antigens and adhesion molecules in hearts of patients with chronic Chagas' disease. Am J Trop Med Hyg 1993; 49:192-200.
13. 13 Laucella SA, de Titto EH, Segura EL, Orn A, Rottenberg ME. Soluble cell adhesion molecules in human Chagas' disease: association with disease severity and stage of infection. Am J Trop Med Hyg 1996; 55:629-34.
14. 14 Tarleton RL, Zhang L, Downs MO. 'Autoimmune rejection' of neonatal heart transplants in experimental Chagas' disease is a parasite-specific response to infected host tissue. Proc Natl Acad Sci USA 1997; 94:3932-7.
15. 15 Sgambatti de Andrade AL, Zicker F, de Oliveira RM et al. Randomized trial of efficacy of benznidazole in treatment of early Trypanosoma cruzi infection. The Lancet 1996; 9039:1407-13.
16. 16 Rassi A. Tratamento específico da doença de Chagas. Uma visāo de 1962 a 1998. Revista Patología Tropical 1998; 27:1-6.
17. 17 Sosa Estani S, Segura EL, Ruiz AM, Velázquez E, Porcel BM, Yampotis C. Efficacy of treatment with benznidazole in children. Am J Trop Med Hyg 1998; 59:526-9.
18. 18 Viotti R, Vigliano C, Armenti H, Segura EL. Treatment of chronic Chagas' disease with benznidazole: clinical and serologic evolution of patients with long-term follow-up. Am Heart J 1994; 127:151-62.
19. 19 Almeida IC, Covas DT, Soussumi LMT, Travassos LR. A highly sensitive and specific chemiluminescent enzyme-linked immunosorbent assay for diagnosis of active Trypanosoma cruzi. Transfusion 1997; 37:850-7.
20. 20 Krautz GM, Galvao LM, Cançado JR, Guevara-Espinosa A, Ouassi A, Krettli A. Use of a 24-kilodalton Trypanosoma cruzi recombinant protein to monitor cure of human Chagas' disease. J Clin Microbiol 1995; 33:2086-90.
21. 21 Galvao LM, Nunes RMB, Cançado JR, Brener Z, Krettli AU. Lytic antibody titer as means of assessing cure after treatment of Chagas disease: a 10 years follow-up study. Trans Roy Soc Trop Med Hyg 1993; 87:220-3.
22. 22 Pigott R, Dillon PL, Hemingway IH, Gearing AJH. Soluble forms of E-selectin, ICAM-1 and VCAM-1 are present in the supernatants of cytokine activated cultured endothelial cells. Biochem Biophys Res Commun 1992; 187:584-9.
23. 23 Ishiwata N, Takio K, Katayama M, Watanabe K, Titani K, Ikeda Y, Handa M. Alternatively spliced isoform of P-Selectin is present in vivo as a soluble molecule. J Biol Chem 1994; 23:23708-15.
24. 24 Lang T, Krams S, Villanueva JC, Cox K, So S, Martínez O. Differential patterns of circulating intercellular adhesion molecule-1 (cICAM-1) and vascular adhesion molecule-1 (cVCAM-1) during liver allograft rejection. Transplantation 1995; 59:584-9.
25. 25 Laucella SA, Salcedo R, Castanos-Vélez E, Riarte A, de Titto EH, Patarroyo M, Orn A, Rottenberg M. Increased expression and secretion of ICAM-1 during experimental infection with Trypanosoma cruzi. Parasite Immunol 1996; 18:227-39.
26. 26 Rossi MA, Carobrez SG. Experimental Trypanosoma cruzi cardiomyopathy in BALB/c: mice: histochemical evidence of hypoxic changes in the myocardium. Br J Exp Pathol 1985; 66:155-60.
27. 27 Tanowitz H, Burns E, Sinha AK et al. Enhanced platelet adherence and aggregation in Chagas' disease: a potential pathogenic mechanism for cardiomyopathy. Am J Trop Med Hyg 1990; 43:274-81.
28. 28 Zhang L, Tarleton RL. Persistent production of inflammatory and anti-inflammatory cytokines and associated MHC and adhesion molecule expression at the site of infection and disease in experimental Trypanosoma cruzi infections. Exp Parasitol 1996; 84:203-13.
29. 29 Tarleton RL, Sun J, Zhang L, Postan M. Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease. Infect Immun 1993; 62:1820-9.
30. 30 Dunlop LC, Skiner MP, Bendall LJ et al. Characterization of GMP-140 (P-selectin) as a circulating plasma protein. J Exp Med 1992; 175:1147-50.
31. 31 Wu G, Li P, Ruan C. Detection of plasma alpha granule membrane protein GMP-140 using radiolabeled monoclonal antibodies in thrombotic diseases. Haemostasis 1993; 23:121-8.
32. 32 Samuel J, Oliveira M, Araujo RCD, Navarro M, Mucilo G. Cardiac thrombosis and thromboembolism in chronic Chagas' heart disease. Am J Cardiol 1983; 52:147-51.
33. 33 Arteaga-Fernández F, Baretto A, Ianni B, Mady C, Lopes E, Vianna C, Belloti G, Pileggi F. Cardiac thrombosis in patients having died of chronic Chagas' cardiopathy. Arq Bras Cardiol 1989; 52:189-92.
34. 34 Becker J, Termeer C, Schmidt R, Brocker E. Soluble intercellular adhesion molecule-1 inhibits MHC-restricted specific T cell/tumor interaction. J Immunol 1993; 151:7224-32.
35. 35 Gearing A, Neumann W. Circulating adhesion molecules in disease. Immunol Today 1993; 14:506-12.
36. 36 Gamble JR, Skinner MP, Berndt MC, Vadas MA. Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP-140. Science 1990; 249:414-7.
37. 37 Munro JM, Lo SK, Corless C, Robertson MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua MP. Expression of sialyl-lewis x, an E-selectin ligand, in inflammation, immune processes, and lymphoid tissues. Am J Pathol 1992; 141:1397-408.
38. 38 Tarleton RL, Grusby MJ, Postan M, Glimcher LH. T. cruzi infection in MHC-deficient mice: further evidence for the role of both class I and class II restricted T cells in immune resistance and disease. Int Immunol 1996; 8:13-22.
39. 39 Cunha-Neto E, Duranti A, Gruber A et al. Autoimmunity in Chagas' disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen. Proc Natl Acad Sci USA 1995; 92:3541-5.
40. 40 Dutra WO, Profeta da Luz MZ, Romeu Cançado J et al. Influence of parasite presence on the immunologic profile of peripheral blood mononuclear cells from chagasic patients after specific drug therapy. Parasite Immunol 1996; 18:579-85.