Effect of nonsedative doses of propofol on an innate anxiogenic situation in rats

Anesthesiology

Volumn 90, Issue 1, 1999, Pages 191-196

  Pain, Laure ^a,d   Oberling, Philippe ^a   Launoy, Anne ^b   Di Scala, Georges ^c  

^a INSERM   (France)

^b Serv d'Anesthesie Reanimation Chir

^c CNRS   (France)

^d HÔPITAL DE HAUTEPIERRE   (France)

Author keywords

Anxiety; Behavior; Diazcpam; Elevated plus shaped maze

Indexed keywords

ANXIOLYTIC AGENT; DIAZEPAM; HYPNOTIC SEDATIVE AGENT; PROPOFOL;

ANIMAL; ANXIETY; ARTICLE; COMPARATIVE STUDY; DRUG EFFECT; EXPLORATORY BEHAVIOR; INTRAPERITONEAL DRUG ADMINISTRATION; LONG EVANS RAT; MALE; MAZE TEST; MOTOR ACTIVITY; PATHOPHYSIOLOGY; RAT;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DIAZEPAM; EXPLORATORY BEHAVIOR; HYPNOTICS AND SEDATIVES; INJECTIONS, INTRAPERITONEAL; MALE; MAZE LEARNING; MOTOR ACTIVITY; PROPOFOL; RATS; RATS, LONG-EVANS;

EID: 0032615062     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199901000-00025     Document Type: Article

References (32)

1. Mackenzie N, Grant IS: Propofol for intravenous sedation. Anaesthesia 1987; 42:3-6
2. Valtonen M, Salonen M, Forsell H, Scheinin M, Viinamäki O: Propofol infusion for sedation in outpatient oral surgery. A comparison with diazepam. Anaesthesia 1989; 44:730-4
3. Grattidge P: Patient-controlled sedation using propofol in day surgery. Anaesthesia 1992; 47:683-5
4. Borgeat A, Wilder-smith OHG, Suter PM: The nonhypnotic therapeutic applications of propofol. ANESTHESIOLOGY 1994; 80:642-54
5. Cook LB, Whitwak JG: New procedures-new sedation techniques: Patient control of intra-operative drug administration. Minimally Invasive Therapy 1994; 3:39-42
6. Rudkin GE, Osborne GA, Curtis NJ: Intra-operative patient controlled sedation. Anaesthesia 1991; 46:90-2
7. Smith I, Monk TG, White PF, Ding Y: Propofol infusion during regional anaesthesia: Sedative, amnestic and anxiolytic properties. Anesth Analg 1994; 79:313-19
8. Geddes SM, Gray WM, Asbury AJ: Skin conductance response in patients sedated with midazolam or propofol. Br J Anaesth 1994; 73:345-9
9. Winwood MA, Jago RH: Anxiety levels following anaesthesia for day-case surgery: A comparison of state anxiety levels following induction of anaesthesia with propofol or thiopentone. Anaesthesia 1993; 48:581-4
10. D'Haese J, Camu F, Dekeyser PJ, D'Haenen HA: Propofol and methohexitone anaesthesia: Effects on the profile of mood state. Eur J Anaesthesiol 1994; 11:359-63
11. Curran HV: Benzodiazepines, memory and mood: A review. Psychopharmacology 1991; 105:1-8
12. Pellow S, Chopin P, File SE, Briley M: Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 1985; 14:149-67
13. Pellow S, File SE: Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat. Pharmacol Biochem Behavior 1986; 24:525-9
14. Handley SL, McBlane JW: An assessment of the elevated plusmaze for studying anxiety and anxiety-modulating drugs. J Pharmacol Toxicol Methods 1993; 29:129-38
15. Dawson GR, Tricklebank MD: Use of elevated plus maze in the search for novel anxiolytic agents. Trends in Pharmacological Sciences 1995; 16:33-6
16. Hoog S: A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav 1996; 54:21-30
17. Treit D, Menard J, Royan C: Anxiogenic stimuli in the elevated plus-maze. Pharmacol Biochem Behav 1993; 44:463-9
18. Graeff FG, Silveira MCL, Nogueira RL, Audi EA, Oliveira RMW: Role of the amygdala and periaqueductal gray in anxiety and panic. Behav Brain Res 1993; 58:123-31
19. Silveira MCL, Sandner G, Graeff FG: Induction of Fos immunoreactivity in the brain by exposure to the elevated plus maze. Behav Brain Res 1993; 56:115-18
20. File SE, Zangrossi H, Sanders FL, Mabbut PS: Raised corticosterone in the rat after exposure to the elevated plus-maze. Psychopharmacology 1994; 113:543-6
21. Dixon WJ: BMDP Statistical Software Manual. Los Angeles, University of California Press, 1988
22. Salonen M, Onaivi ES, Maze M: Dexmedetomine synergism with midazolam in the elevated plus-maze test in rats. Psychopharmacology 1992; 108:229-34
23. Killcross AS, Everitt BJ, Robbins TW: Symetrical effects of am-phetamine and alpha-flupenthixol on conditioned punishment and conditioned reinforcement: Contrasts with midazolam. Psychopharmacology 1997; 129:141-52
24. Shephard RA. Neurotransmitters, anxiety and benzodiazepines: A behavioral review. Neurosci Biobehav Rev 1986; 10:449-61
25. Shekhar A, Sims LS, Bowsher RR: GABA receptors in the region of the dorsomedial hypothalamus of rats regulate anxiety in the elevated plus-maze test. II. Physiological measures. Brain Res 1993; 627: 17-24
26. Concas A, Santoro G, Serra M, Sanna E, Biggio G: Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors. Brain Res 1991; 542:225-32
27. Hales TG, Lambert JJ: The action of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. Br J Pharmacol 1991; 104:619-28
28. Adodra S, Hales TG: Potentiation, activation and blockade of GABAA receptors of clonal murine hypothalamic GT1-7 neurones by propofol. Br J Pharmacol 1995; 115:953-60
29. Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA: Actions of the general anesthetic propofol on recombinant human GABAA receptors: Influence of receptors subunits. J Pharmacol Exper Ther 1995; 274:353-60
30. Hara M, Kai Y, Ikemoto Y: Propofol activates GABAA receptorchloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. ANESTHESIOLOGY 1993; 79:781-8
31. Orser BA, Wang L, Pennefather PS, MacDonald JF: Propofol modulates activation and desensitization of GABAA receptors in cultured murine hippocampal neurons. J Neurosci 1994; 14:7747-60
32. Pain L, Oberling P, Sandner G, Di Scala G: Effect of propofol on affective state as assessed by place conditioning in rat. ANESTHESIOLOGY 1996; 85:121-8