Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides

Biospectroscopy

Volumn 5, Issue 2, 1999, Pages 79-91

  Spencer, D I R ^a   Missailidis, S ^a   Denton, G ^a   Murray, A ^a   Brady, K ^a   Matteis, C I D ^a   Searle, M S ^a   Tendler, S J B ^a   Price, M R ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Antibody; Circular dichroism; Fluorescence; Glycopeptide; MUC1 mucin; Nuclear magnetic resonance spectroscopy

Indexed keywords

ASPARTIC ACID; CA 15-3 ANTIGEN; EPITOPE; GLUTAMIC ACID; GLYCOPEPTIDE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MUC1 MUCIN PEPTIDE; PEPTIDE FRAGMENT; TRYPTOPHAN; TYROSINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING COMPETITION; CHEMISTRY; CIRCULAR DICHROISM; GLYCOSYLATION; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PROTEIN DENATURATION; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TEMPERATURE; THERMODYNAMICS; TITRIMETRY;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ASPARTIC ACID; BINDING, COMPETITIVE; CA-15-3 ANTIGEN; CIRCULAR DICHROISM; EPITOPES; GLUTAMIC ACID; GLYCOPEPTIDES; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULIN G; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN DENATURATION; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE; THERMODYNAMICS; TITRIMETRY; TRYPTOPHAN; TYROSINE;

EID: 0032612542     PISSN: 10754261     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1520-6343(1999)5:2<79::aid-bspy2>3.0.co;2-%23     Document Type: Article

References (42)

1. Gendler, S.; Taylor-Papadimitriou, J.; Duhig, T.; Rothbard, J.; Burchell, J. J Biol Chem 1988, 263, 12820-12823.
2. Gendler, S. J.; Spicer, A. P.; Lalani, E.-N.; Duhig, T.; Peat, N.; Burchell, J.; Pemberton, L.; Boshell, M.; Taylor-Papadimitriou, J. Ann Rev Respir Dis 1991, 144, S42-S47.
3. Patton, S.; Gendler, S. J.; Spicer, A. P. Biochim Biophys Acta 1995, 1241, 407-424.
4. Hull, S. R.; Carraway, K.L. FASEB J 1988, 2, 2380-2384.
5. Brockhausen, I.; Yang, J.-M.; Burchell, J.; Whitehouse, C.; Taylor-Papadimitriou, J. Eur J Biochem 1995, 233, 607-617.
6. Terada, T.; Nakanuma, Y. Am J Clin Path 1996, 105, 613-620.
7. Itzkowitz, S. H.; Yuan, M.; Montgomery, C. K.; Kjeldsen, T.; Takahashi, H. K.; W. L.; Bigbee, Y. S. Kim, Cancer Res 1989, 49, 197-204.
8. Tashiro, Y.; Yonezawa, S.; Kim, S.; Sato, E. Human Path 1994, 25, 364-372.
9. Springer, G. F. Crit Rev Oncogenesis 1995, 6, 57-85.
10. Spencer, D. I. R.; Price, M. R.; Tendler, S. J. B.; De Matteis, C. I.; Stadie, T.; Hanisch, F.-G. Cancer Lett 1996, 100, 11-15.
11. Tetin, S. Y.; Linthicum, D.S. Biochemistry 1996, 35, 1258-1264.
12. Tetin, S. Y.; Mantulin, W. W.; Denzin, L. K.; Weidner, K. M.; Voss, Jr., E. W. Biochemistry 1992, 31, 12029-12034.
13. Greenstein, J. P. J Biol Chem 1931, 93, 479,
14. in CRC Handbook of Chemistry and Physics; Weast, R.C., Astle, M. J., Eds.; CRC Press: FL, section C, 1979, pp 757.
15. Simms, J.S. J Gen Physiol 1928, 11, 629;
16. Simms, J.S. J Gen Physiol 12, 231,
17. in CRC Handbook of Chemistry and Physics; Weast, R. C., Astle, M. J., Eds.; CRC Press, FL, section C, 1979, pp 757.
18. Winnek, P.S.; Schmidt, C.L.A. J Gen Physiol 1935, 18, 889,
19. in CRC Handbook of Chemistry and Physics; Weast, R. C., Astle, M. J., Eds.; CRC Press, FL, section C, 1979, pp 757.
20. Siligardi, G.; Drake, A. F. Biopolymers 1995, 37, 281-292.
21. Helbecque, N.; Loucheux-Lefebvre, M. H. Int J Pep Protein Res 1982, 19, 94-101.
22. Dalcol, I.; Pons, M.; Ludevid, M-D; Giralt, E. J Org Chem 1996, 61, 6775-6782.
23. Venugopal, M. G.; Ramshaw, J. A. M.; Braswell, E.; Zhu, D.; Brodsky, B. Biochemistry 1994, 33, 7948-7956.
24. Drake, A. F.; Siligardi, G.; Gibbons, W. A. Biophys Chem 1988, 31, 143-146.
25. Missailidis, S.; Cannon, W.V.; Drake, A.; Wang; X.Y.; Buck, M. Molecular Microbiology 1997, 24, 653.
26. Wüthrich. K. In NMR of Proteins and Nucleic Acids; Wuthrick, K., Ed.; Wiley: New York, 1986.
27. Mouritsen, S.; Meldal, M.; Christiansen-Brams, I.; Elsner, H.; Werdelin, O. Eur J Immunol 1994, 24, 1066-1072.
28. Otvos, Jr., L.; Thurin, J.; Kollat, E.; Urge, L.; Mantsch, H. H.; Hollosi, M. Int J Pept Prot Res 1991, 38, 476-482.
29. Urge, L.; Gorbics, L.; Otvos, Jr. , L. Biochem Biophys Res Comm 1992, 184, 1125-1132.
30. Fontenot, J. D.; Mariappan, S. V. S.; Catasti, P.; Domenech, N.; Finn, O.J.; Gupta, G. J Biomolec Struct and Dynam 1995, 13, 245-260.
31. Fontenot, J. D.; Tjandra, N.; Bu, D.; Ho, C.; Montelaro, R. C.; Finn, O. J. Cancer Res 1993, 53, 5586-5394.
32. Mimura, Y.; Inoue, Y.; Maeji, N.J.; Chûjô, R. Int J Pept Prot Res 1989, 34, 363-368.
33. Mimura, Y.; Yamamoto, Y.; Inoue, Y.;. Chûjô, R Int J Biol Macromol 1992, 14, 242-248.
34. Meinjohanns, E.; Vargas-Berenguel, A.; Meldal, M.; Paulsen, H.;. Bock, K. J Chem Soc Perk Trans 1, 1995, 17, 2165-2175.
35. Stadie, T. R. E.; Chai, W.; Lawson, A. M.; Byfield, P. G. H.; Hanisch, F.-G. Eur J Biochem 1995, 229, 140-147.
36. Price, M. R.; Pugh, J. A.; Hudecz, F.; Griffiths, W.; Jacobs, E.; Symonds, I. M.; Clark, A. J.; C.; Chan, W. C.; Baldwin, R. W. Br J Cancer 1990, 61, 681-868.
37. Price, M. R.; Sekowski, M.; Ladanyi, A.; Uray, K.; Ma, Y.; Durrant, L., Tendler, S. J. B. Int J Cancer 1993, 55, 753-759.
38. Hudecz, F.; Price, M. R. J Immunological Methods 1992, 147, 201-210.
39. Jensenius, J.C.; Williams, A. F. Eur J Immunol 1974, 4, 91.
40. Hennessey, Jr., J. P.; Johnson, Jr., W. C. Biochemistry 1981, 20, 1085-1094.
41. Compton, L. A.; Johnson, Jr., W. C. Anal Biochem 1986,155, 155-167.
42. Manavalan, P.; Johnson, Jr., W. C. Anal Biochem 1987, 167, 76-85.