Multilocus approach to cardiovascular risk

Scandinavian Journal of Clinical and Laboratory Investigation, Supplement

Volumn 59, Issue 230, 1999, Pages 168-176

  Pallaud, C ^a   Maurice, M ^a   Cheng, S ^b   Grow, M ^b   Aguillon, D ^a   Sass, C ^a   Siest, G ^a   Visvikis, S ^a  

^a Centre de Medecine Preventive   (France)

^b ROCHE MOLECULAR SYSTEMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; APOLIPOPROTEIN A4; APOLIPOPROTEIN B; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; ARYLDIALKYLPHOSPHATASE; CHOLESTEROL ESTER TRANSFER PROTEIN; CYSTATHIONINE BETA SYNTHASE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FIBRINOGEN; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; ANTIOXIDANT; APOLIPOPROTEIN A; APOLIPOPROTEIN A-IV; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

CARDIOVASCULAR RISK; CONFERENCE PAPER; DNA POLYMORPHISM; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; LIPID METABOLISM; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; ADULT; ARTICLE; BLOOD; CARDIOVASCULAR DISEASE; CHILD; COHORT ANALYSIS; FAMILY HEALTH; FEMALE; GENETIC MARKER; GENETICS; HAPLOTYPE; MALE; METABOLISM; RISK FACTOR;

ADULT; ANTIOXIDANTS; APOLIPOPROTEINS A; APOLIPOPROTEINS B; APOLIPOPROTEINS E; CARDIOVASCULAR DISEASES; CHILD; CHOLESTEROL, LDL; COHORT STUDIES; FAMILY HEALTH; FEMALE; GENETIC MARKERS; GENOTYPE; HAPLOTYPES; HUMANS; MALE; POLYMORPHISM, GENETIC; RISK FACTORS; TRIGLYCERIDES;

EID: 0032609690     PISSN: 0085591X     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365519909168340     Document Type: Conference Paper

References (15)

1. Cheng S, Pallaud C, Grow MA, Scharf SJ, Erlich HA, Klitz W, Pullinger CR, Malloy MJ, Kane JP, Siest G, Visvikis S, A multilocus genotyping assay for cardiovascular disease, Clin. Chem. Lab Med. 1998; 36(8):561-566.
2. Siest G, Visvikis S, Herbeth B, Gueguen R, Vincent-Viry M, Sass C, Beaud B, Lecomte E, Steinmetz J, Locuty J, Chevrier P, Objectives, design and recruitement of a familial and longitudinal cohort for studying gene-environment interactions in the field of cardiovascular risk : The Stanislas Cohort, Clin. Chem. Lab Med. 1998; 36(1):35-42.
3. Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res. 1988; 16: 1215.
4. Bonnet K, Régis-Bailly A, Vincent-Viry M, Schlenck A, Gueguen R, Siest G, Visvikis S, Apolipoprotein E genotype ε4/ε2 in the STANISLAS Cohort Study-Dominance of the ε2 allele?, Ann. Hum. Genet. 1996; 60:509-16.
5. Hallman DM, Visvikis S, Steinmetz J, Boerwinckle E, The effect of variation in the apoliporpotein B gene on plasma lipid and apolipoprotein B levels, Ann. Hum. Genet. 1994; 58:35-64.
6. Zaiou M, Visvikis S, Gueguen R, Parra HJ, Fruchart JC, Siest G, DNA polymorphisms of human apolipoprotein A-IV gene: frequency and effects on lipid, lipoprotein and apolipoprotein levels in a french population, Clin. Genet. 1994; 46:248-254.
7. Salah D, Bohnet K, Gueguen R, Siest G, Visvikis S, Combined effects of lipoprotein lipase and apolipoprotein E polymorphisms on lipid and lipoprotein levels in the Stanislas Cohort, J. Lipid Res. 1997; 38:904-912.
8. Georges JL, Régis-Bailly A, Salah D, Rakotovao R, Siest G, Visvikis S, Tiret L, Family study of lipoprotein lipase gene polymorphisms and plasma triglyceride levels, Genetic Epidemiol. 1996; 13:179-192.
9. Lange K, Weeks D, Boehnke M, programs for pedigree analysis : Mendel, fisher, and d gene, Genetic Epidemiol 1988;5:471-472.
10. Lange K, Westlake J, Spence MA, Extensions to pedigree analysis. III. Variance components by the scoring method, Ann. Hum. Genet. 1976;39:485-491.
11. Tenkanen H, Lukka M, Jauhiainen M, Mesto J, Baumann M, Pelton L, Ehnholm C, The mutation causing the common apolipoprotein A-IV polymorphism is a glutamine to histidine substitution of amino acid 360, Arterioscler. Thromb. 1991; 11:851-856.
12. Tenkanen H, Ehnholm C, Molecular basis for apo A-IV polymorphisms, Ann. Med. 1992; 24:369-374.
13. Von Eckardstein A, Funke H, Schulte M, Erren M, Shulte H, Assmann G, Nonsynonymous polymorphic sites in the apolipoprotein (apo) A-IV gene are associated with changes in the concentration of apo B and apo A-I containing lipoproteins in a normal population, Am. J. Hum. Genet. 1992; 50:1115-1128.
14. Zaiou M, Visvikis S, Gueguen R, Steinmetz J, Parra HJ, Fruchart JC, Siest G, Sources of variability of human plasma apolipoprotein A-IV levels and relationships with lipid metabolism, Genetic Epidemiol 1994;11:101-114.
15. Boerwinkle E, Visvikis S, Welsh D, Steinmetz J, Hanash S, Sing CF, The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability and covariability of cholesterol, betalipoprotein and triglycerides in a sample of unrelated individuals, Ann of Hum Genet 1987;27:567-82