Regulation of IgE synthesis: The molecular basis and implications for clinical modulation

Allergy and Asthma Proceedings

Volumn 20, Issue 1, 1999, Pages 1-8

  Bacharier, Leonard B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIALLERGIC AGENT; CYTOKINE; IMMUNOGLOBULIN E;

BIOSYNTHESIS; CELLULAR IMMUNITY; DRUG EFFECT; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; MOLECULAR BIOLOGY; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION;

ANTI-ALLERGIC AGENTS; CYTOKINES; HUMANS; HYPERSENSITIVITY, IMMEDIATE; IMMUNITY, CELLULAR; IMMUNOGLOBULIN E; MOLECULAR BIOLOGY; SIGNAL TRANSDUCTION;

EID: 0032609110     PISSN: 10885412     EISSN: None     Source Type: Journal    
DOI: 10.2500/108854199778681558     Document Type: Article

References (7)

1. Shapira S, Vercelli D, Jabara H, Fu S, Geha R. Molecular analysis of the induction of Immunoglobulin E synthesis by human B cells by interleukin 4 and engagement of CD40 antigen. J Exp Med 175:289-292, 1992.
2. Vercelli D, Jabara H, Arai K-I, Geha R. Induction of human IgE synthesis requires interleukin 4 and T/B interactions involving the T cell receptor/CD3 complex and MHC class II antigens. J Exp Med 169:1295-1307, 1989.
3. Clark E, Ledbetter J. How B and T cells talk to each other. Nature 367:425-428, 1994.
4. Del Prete G, Maggi E, Parronchi P, et al. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cells clones and their supernatants. J Immunol 140:4193-4198, 1988.
5. Gauchat J-F, Lebman D, Coffman R, et al. Structure and expression of germline ε transcripts in human B cells induced by interleukin 4 to switch to IgE production. J Exp Med 172:463-473, 1990.
6. Punnonen J, Aversa G, Cocks B, et al. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc Natl Acad Sci USA 90:3730-3734, 1993.
7. Banchereau J, Bazan F, Blanchard D, et al. The CD40 antigen and its ligand. Annu Rev Immunol 12:881-922, 1994.