Lead and mercury mutagenesis: Type of mutation dependent upon metal concentration

Journal of Biochemical and Molecular Toxicology

Volumn 13, Issue 2, 1999, Pages 107-112

  Ariza, Maria E ^a,b   Williams, Marshall V ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

AS52 Cells; Lead; Mercury; Mutagenesis

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LEAD; MERCURY; MUTAGENIC AGENT; PRIMER DNA;

ANIMAL; ARTICLE; CELL LINE; DOSE RESPONSE; GENETICS; HAMSTER; HUMAN; MUTATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ANIMALS; BASE SEQUENCE; CELL LINE; CRICETINAE; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LEAD; MERCURY; MUTAGENS; MUTATION; POLYMERASE CHAIN REACTION;

EID: 0032608482     PISSN: 10956670     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0461(1999)13:2<107::AID-JBT6>3.0.CO;2-0     Document Type: Article

References (30)

1. Vallee BL, Ulmer DD. Biochemical effects of mercury, cadmium and lead. Annu Rev Biochem 1972; 41:91-145.
2. US EPA (Environmental Protection Agency). Review of the National Ambient Air Quality Standard for Lead: exposure, analysis, methodology and validation. EPA Of-fice of Air Quality Office Planning and Standards EPA 450/2-89-011. 1989.
3. US EPA (Environmental Protection Agency) and Agency for Toxic Substances and Disease Registry, US Public Health Service. Toxicological profile for mercury. Clement Assoc. #205-88-0608. 1989.
4. US EPA (Environmental Protection Agency) and Agency for Toxic Substances and Disease Registry, US Public Health Service. Toxicological profile for lead. Syracuse Research Corp. #68-C8-0004. 1990.
5. Schweinsberg F, von Karsa L. Heavy metal concentrations in humans. Comp Biochem Physiol 1990; 95:117-123.
6. Kazantis G. Role of cobalt, iorn, lead, manganese, mercury, platinum, selenium and titanium in carcinogenesis. Environ Health Perspect 1981; 40:143-161.
7. Leonard A, Jacquet P, Lauwerys RR. Mutagenicity and teratogenicity of mercury compounds. Mutat Res 1982; 114:1-18.
8. Heck JD, Costa M. In vitro assessment of the toxicity of metal compounds. II. Mutagenesis. Biol Trace Met Res 1982; 4:319-330.
9. Gebhart E. Chromosome damage in individuals exposed to heavy metals. Toxicol Environ Chem 1984; 8:253-265.
10. Hansen K, Stern RM. A survey of metal-induced mutagenicity in vitro and in vivo. Toxicol Environ Chem 1984; 9:87-91.
11. Ariza ME, Williams MV. Mutagenesis of AS52 cells by low concentrations of lead (II) and mercury (II). Environ Mol Mutagen 1996; 27:30-33.
12. 2, Superoxide dismutase and xanthine oxidase. Environ Mol Mutagen 1998; 31:352-361.
13. Tindall KR, Stankowski LF, Machanoff R, Hsie AW. Analyses of mutation in pSV2gpt transformed CHO cells. Mutat Res 1986; 160:121-131.
14. Tindall KR, Stankowski LF, Machanoff R, Hsie AW. Detection of deletion mutations in pSV2gpt transformed cells. Mol Cell Biol 1987; 4:1411-1415.
15. Tindall KR, Stankowski LF. Molecular analysis of spontaneous mutations at the gpt locus in Chinese hamster ovary (AS52) cells. Mutat Res 1989; 220:241-253.
16. Yamane T, Davidson N. On the complexing of desoxyribonucleic acid (DNA) by mercuric ion. J Am Chem Soc 1961; 83:2599-2607.
17. Nandi US, Wang JC, Davidson N. Separation of deoxyribonucleic acids by Hg(II) binding and Cs2SO4 density-gradient centrifugation. Biochemistry 1965; 4:1687-1696.
18. Sissoeff I, Grisuard J, Guille E. Studies on metal ions-DNA interactions: Specific behavior of reiterated DNA sequences. Prog Biophys Molec Biol 1976; 31:165-169.
19. Kunkel TA, Soni A. Mutagenesis by transient misalignment. J Biol Chem 1988; 263:14784-14789.
20. Kunkel TA. Misalignment-mediated DNA synthesis errors. Biochemistry 1990; 29:8003-8011.
21. Kunkel TA. Slippery DNA and diseases. Nature 1993; 365:207-208.
22. Sirover MA, Loeb LA. Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens. Science 1976; 194:1434-1436.
23. Zakour RA, Kunkel TA, Loeb LA. Metal-induced infidelity of DNA synthesis. Environ Health Perspect 1981; 40:197-205.
24. Costa M, Cantoni O, deMars M, Swartzendruber D. Toxic metals produce an S-phase specific cell cycle block. Res Comm Chem Pathol Pharmacol 1982; 38:405-419.
25. Robison SH, Cantoni O, Costa M. Analysis of metal-induced DNA lesions and DNA-repair replication in mammalian cells. Mutat Res 1984; 131:173-181.
26. Williams MV, Winters T, Waddell K. In vitro effects of mercury (II) on deoxyuridine triphosphate nucleotidohydrolase, DNA polymerase (∂, β), and uracil-DNA glycosylase activities in cultured human cells: relationship to DNA damage, DNA repair and cytotoxicity. Mol Pharmacol 1987; 31:200-207.
27. Popenoe EA, Schmaeler MA. Interaction of human DNA polymerase β with ions of copper, lead and cadmium. Arch Biochem Biophys 1979; 196:109-120.
28. Cantoni O, Costa M. Correlations of DNA strand breaks and their repair with cell survival following acute exposure to mercury (II) and X-rays. Mol Pharmacol 1983; 24:84-87.
29. Christie NT, Cantoni O, Sugiyama M, Cattabeni F, Costa M. Differences in the effects of Hg (II) on DNA repair induced in Chinese hamster ovary cells by ultraviolet or X-rays. Mol Pharmacol 1985; 29:173-178.
30. Heck JD, Costa M. In vitro assessment of the toxicity of metal compounds. I. Mammalian cell transformation. Biol Trace Element Res 1982; 4:71-82.