Polymorphisms of the p53 gene in women with ovarian or endometrial carcinoma

Oncology Reports

Volumn 6, Issue 1, 1999, Pages 193-197

  Peller, Shoshana ^a   Halperin, Rehuvit ^a   Schneider, David ^a   Kopilova, Yulia ^a   Rotter, Varda ^b  

^a ASSAF HAROFEH MEDICAL CENTER   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Endometrial carcinoma; Ovarian carcinoma; p53 polymorphism; p53 tumor suppressor gene

Indexed keywords

DNA;

ADULT; AGED; ALLELE; ARTICLE; CARCINOMA; CHEMISTRY; CODON; COMPARATIVE STUDY; ENDOMETRIUM TUMOR; EXON; FEMALE; GENE DUPLICATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY LOSS; HUMAN; INTRON; ISRAEL; LYMPHOCYTE; MIDDLE AGED; OVARY TUMOR; POLYMERASE CHAIN REACTION; RISK FACTOR; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; CARCINOMA; CODON; DNA; ENDOMETRIAL NEOPLASMS; EXONS; FEMALE; GENE DUPLICATION; GENES, P53; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HAPLOTYPES; HUMANS; INTRONS; ISRAEL; LOSS OF HETEROZYGOSITY; LYMPHOCYTES; MIDDLE AGED; OVARIAN NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK FACTORS;

EID: 0032608350     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.6.1.193     Document Type: Article

References (26)

1. Hollstein M, Sidransky D, Vogelstein B and Harris CC: p53 mutation in human cancers. Science 253: 49-53, 1991.
2. Caron De-Fromental C and Soussi T: The p53 tumor suppressor gene: A model for investigating human mutagenesis. Genes Chromosomes Cancer 4: 1-15, 1992.
3. Kihana T, Hamada K, Inoue Y, Yano N, Iketani H, Murao S-I, Ukita M and Matsuura S: Mutation and allelic loss of the p53 gene in endometrial carcinoma. Cancer 76: 72-78, 1995.
4. Li S-F, Shiozawa T, Nakayama K, Nikaido T and Fujii S: Stepwise abnormality of sex steroid hormone receptors, tumor suppressor gene products (p53 and Rb), and cyclin E in uterine endometrioid carcinoma. Cancer 77: 321-329, 1996.
5. Strang P, Nordstrom B, Nilsson S, Bergstrom R and Tribukait B: Mutant p53 protein as a predictor of survival in endometrial carcinoma. Eur J Cancer 32A: 598-602, 1996.
6. Sherman ME, Bur ME and Kurman RJ: p53 in endometrial cancer and its putative precursors: evidence for diverse pathways of tumorigenesis. Hum Pathol 26: 1268-1274, 1995.
7. Hartman L, Podarartz K, Keeney G, et al: Prognostic significance of p53 immunostaining in epithelial ovarian cancer. J Clin Oncol 12: 64-69, 1994.
8. S. Henriksen R, Strang P, Wilander E, Backstrom T, Tribukait B and Oberg K: p53 expression in epithelial ovarian neoplasm: relationship to clinical and pathological parameters. Ki-67 expression and flow cytometry. Gynecol Oncol 53: 301-306, 1994.
9. Harris N, Brill E, Shohat O, Prokocimer M, Wolf D, Arai N and Rotter V: The molecular basis for heterogeneity of the human p53 protein. Mol Cell Biol 6: 4650-4656, 1986.
10. Matlashewski GJ, Tuck S, Pim D, Lamb P, Schneider J and Craford LV: Primary structure polymorphism at amino acid residue 72 of human p53. Mol Cell Biol 7: 961-963, 1987.
11. Zhang W, Hu G and Deisseroth A: Polymorphism at codon 72 of the p53 gene in human acute myelogenous leukemia. Genes 117: 271-275, 1992.
12. Miwa H. Kita K, Saya H, Otsuji A, Masuya M, Nishii K, Morita N. Takakura N, Oshishi K and Nasu K: Structural alterations of the p53 gene in human leukemias. Leuk Res 16: 1105-1112, 1992.
13. Weston A, Ling-Cawley HM, Caporaso NE, Bowman Ed, Hoover RN, Trump BF and Harris CC: Determination of the allelic frequencies of an L-myc and a p53 polymorphism in human lung cancer. Carcinogenesis 15: 583-587, 1994.
14. Kawajiri K, Nakachi K, Imai K, Wantanabe J and Hayashi S-I: Germ-line polymorphism and CYP1A1 genes involved in human lung cancer. Carcinogenesis 14: 1085-1089, 1993.
15. Murata M, Tagawa M, Kimura M, Kimura H, Watanabe S and Saisho H: Analysis of a germ line polymorphism of the p53 gene in lung cancer patients; discrete results with smoking history. Carcinogenesis 17: 261-264, 1996.
16. Felley-Bosco E, Weston A, Cawley HM, Bennett WP and Harris CC: Functional studies of a germ-line polymorphism at codon 47 within the p53 gene. Am J Genet 53: 752-759, 1993.
17. Hahn M. Serth J, Fislage R, Wolfes H, Allohoff E, Jonas U and Pingoud A: Polymerase chain reaction detection of a highly polymorphic VNTR segment in intron 1 of the human p53 gene. Clin Chem 39: 549-550, 1993.
18. Willems PM, Meyerink JP, Van-de-Locht LT, Smeters TF, De-Vries N, and Mensink EJ: PCR detection of a BglII polymorphism in intron 1 of the human p53 gene. Nucleic Acids Res 20: 1172, 1992.
19. Bhatia K, Gutierrez MI, Huppi K and Magrath IT: PCR detection of a neutral CGA/CGG dimorphism in exon 6 of the human p53 gene. Nucleic Acids Res 20: 928, 1992.
20. Serra A, Gaidano GL and Revello D: A new TaqI polymorphism in the p53 gene. Nucleic Acids Res 20: 928, 1992.
21. Lazar V, Hazard F, Bertin F, Janin N, Bellet D and Bressac B: Simple sequence repeat polymorphism within the p53 gene. Oncogene 8: 1703-1705, 1993.
22. Peller S, Kopilova Y, Slutzki S, Halevy A and Rotter V: Association of a novel polymorphism in intron 6 of the human p53 gene with predisposition and susceptibility to cancer. DNA Cell Biol 14: 983-990, 1995.
23. Sjalander A, Birgander R, Hallmans G, Cajander S, Lenner P, Athlin L, Beckman G and Beckman L: p53 polymorphisms and haplotypes in breast cancer. Carcinogenesis 17: 1313-1316, 1996.
24. Sjalander A, Birgander R, Kivela A and Beckman G: p53 polymorphisms and haplotypes in different ethnic groups. Hum Hered 45: 144-149, 1995.
25. Birgander R, Sjlander A, Rannug A, Alexandrie A-K, Ingelman Sundberg M, Seidegard J, Tornling G. Beckman G and Beckman L: p53 polymorphisms and haplotypes in lung cancer. Carcinogenesis 16: 2233-2236, 1995.
26. Salander A, Birgander R, Athlin L, Stenling R, Rutegard J, Beckman L and Beckman G: p53 germ line haplotypes associated with increased risk for colorectal cancer. Carcinogenesis 16: 1461-1464, 1995.