Use of itraconazole as prophylaxis of systemic aspergillosis in neutropenic patients : Interest of drug monitoring;Prophylaxie de l'aspergillose par l'itraconazole chez les patients neutropéniques : Valeur des dosages plasmatiques

Bulletin de l'Academie Nationale de Medecine

Volumn 183, Issue 2, 1999, Pages 371-381

  Cheymol, Georges ^a   Poirier, Jean Marie ^b  

^a HÔPITAL SAINT ANTOINE   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ITRACONAZOLE;

ARTICLE; ASPERGILLOSIS; BLOOD; CASE CONTROL STUDY; DRUG MONITORING; HUMAN; METHODOLOGY; MICROBIOLOGY; NEUTROPENIA;

ANTIFUNGAL AGENTS; ASPERGILLOSIS; CASE-CONTROL STUDIES; DRUG MONITORING; HUMANS; ITRACONAZOLE; NEUTROPENIA;

EID: 0032604275     PISSN: 00014079     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. JOLY V., YENI P. - Antifongiques : données générales. In Carbon C., Regnier B., Saimot G., Vildé J.-L., Yeni P. Médicaments anti-infectieux. Paris : Médecine Sciences Flammarion, 1994, 449-453.
2. GRANT S.M., CLISSOLD S.P. - Itraconazole. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses. Drugs, 1989, 37, 310-344.
3. HARDIN T.C., GRAYBILL J.R., FETCHNICK R., WOESTENBORGHS R., RINALDI M.G., KUHN G. -Pharmacokinetics of itraconazole following oral administration to normal volunteers. Antimicrob. Agents Chemother., 1988, 32, 1310-1313.
4. HEYKANTS J., VAN PEER A., VAN de VELDE V., VAN ROOY P., MEULDERMANS W., LAVRIJSEN K., WOESTENBORGHS R., VAN CUSTEM J., CAUWENBERGH G. - The clinical pharmacokinetics of itraconazole : an overview. Mycoses, 1989, 32 (suppl.1), 67-87.
5. ZIMMERMANN T., YEATES R.A., LAUFEN H., PFAFF G., WILDFEUER A. - Influence of concomitant food intake on oral absorption of two triazole antifungal agents, itraconazole and fluconazole. Eur. J. Clin. Pharmacol., 1994, 46, 147-150.
6. VAN de VELDE V.J.S., VAN PEER A.P., HEYKANTS J.J.P., WOESTENBORGHS J.H., VAN ROOY P., DE BEULE K.L., CAUWENBERGH G.F.M.J. - Effect of food on the pharmacokinetics of a new hydroxypropyl-β-cyclodextrin formulation of itraconazole. Pharmacology, 1996, 16, 424-428.
7. SCHÄFER-KÖRTING M. - Pharmacokinetic optimisation of oral antifungal therapy. Clin. Pharmacokinet, 1993, 25, 329-341.
8. BOELAERT J., SCHURGERS M., MATTHYS E., DANEELS R., VAN PEER A., DE BEULE K., WOESTENBORGHS R., HEYKANTS J. - Itraconazole pharmacokinetics in patients with renal dysfunction. Antimicrob. Agents Chemother., 1988, 32, 1595-1597.
9. LAZO DE LA VEGA S., VOLKOW P., YEATES R.A., PFAFF G. - Administration of the antimycotic agents fluconazole and itraconazole to leukaemia patients : a comparative pharmacokinetic study. Drugs Under Exper. Clin. Res., 1994, 20, 69-75.
10. SMITH D., VAN de VELDE V., WOESTENBORGHS R., GAZZARD B.G. The pharmacokinetics of oral itraconazole in AIDS patients. J. Pharm. Pharmacol., 1992, 44, 618-619.
11. REX J.H., PFALLER M.A., GALGIANI J.N., BARTLETT M.A., ESPINEL-INGROFF A., GHANNOUM M.A., LANCASTER M., ODDS F.C., RINALDI M.G., WALSH T.J., BARRY A.L. - Development of interpretative breakpoints for antifungal susceptibility testing : conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and Candida infections. Clin. Infect. Dis., 1997, 24, 235-247.
12. BOOGAERTS M.A., VERHOEF G.E., ZACHEE P., DEMUYNCK H., VERBIST L., DE BEULE K. -Antifungal prophylaxis with itraconazole in prolonged neutropenia : correlation with plasma levels. Mycoses, 1989, 32 (suppl. 1), 103-108.
13. TRICOT G., JOOSTEN E., BOOGAERTS M.A., VAN DEPITTEJ., CAUWENBERGH G. - Ketoconazole vs. itraconazole for antifungal prophylaxis in patients with severe granulocytopenia : preliminary results of two nonrandomized studies. Rev. Infect. Dis., 1987, 9 (suppl. 1), S94-S99.
14. BRADFORD C.R., PRENTICE A.G., WARNOCK D.W., COPPLESTONE J.A. - Comparison of the multiple dose pharmacokinetics of two formulations of itraconazole during remission induction for acute myeloblastic leukaemia. J. Antimicrob. Chemother., 1991, 28, 555-560.
15. GLASMACHER A., MOLITOR E., HAHN C., BOMBA K., EWIG S., LEUTENER C., WARDELMANN E., SCHMIDT-WOLF IGH., MEZGER J., MARKLEIN G., SAUERBRUCH T. - Antifungal prophylaxis with itraconazole in neutropenic patients with acute leukaemia. Leukemia, 1998, 12, 1338-1343.
16. LAMY T., BERNARD M., COURTOIS A., JACQUELINET C., CHEVRIER S., DAURIAC C., GRULOIS I., GUIGUEN C., LE PRISE PY. - Prophylactic use of itraconazole for the prevention of invasive pulmonary aspergillosis in high risk neutropenic patients. Leukemia Lymphoma, 1998, 30, 163-174.
17. POIRIER J.-M., BERLIOZ F., ISNARD F., CHEYMOL G. - Marked intra and inter-patient variability of itraconazole steady plasma concentrations. Thérapie, 1996, 51, 163-167.
18. POIRIER J.-M., CHEYMOL G. - A rapid and specific liquid chromatographic assay for the determination of itraconazole and hydroxyitraconazole in plasma.Ther. Drug Monit., 1997, 19, 247-248.
19. LEVRON J.-C., LE MOING A., CHWETZOFF E. Exemple d'un suivi thérapeutique actif : l'itraconazole. Thérapie, 1996, 51, 502-506.
20. PERSAT F., MARZULLO C., GUYOTAT D., ROCHET M.J., PIENS M.A. - Plasma itraconazole concentrations in neutropenic patients after repeated high-dose treatment. Eur. J. cancer., 1992, 28A, 838-841.
21. PETROPOULOU T., LIESE J., TINTELNOT K., GAHR M., BELOHRADSKY B.H. - Long-term treatment of patients with chronic granulomatous disease (CGD) for prophylaxis against Aspergillus infections. Mycoses, 1994, 37 (suppl.2), 64-69.
22. PRENTICE A.G., WARNOCK D.W., JOHNSON S.A.N., TAYLOR P.C., OLIVER D.A. - Multiple dose pharmacokinetics of an oral solution of itraconazole in patients receiving chemotherapy for acute myeloid leukaemia. J. Antimicrob. Chemother., 1995, 36, 657-663.
23. POIRIER J.M., HARDY S., ISNARD F., TILLEUL P., WEISSENBURGER J., CHEYMOL G. - Plasma itraconazole concentrations in patients with neutropenia : advantages of a divided daily dosage regimen. Ther. Drug Monitor., 1997, 19, 525-529.
24. GRAYBILL J.R. - Is there a correlation between serum antifungal drug concentration and clinical outcome? J. Infection, 1994, 28 (suppl.), 17-24.