The effect of cyclopiazonic acid on the development of pale, soft, and exudative pork from pigs of defined malignant hyperthermia genotype

Journal of Animal Science

Volumn 77, Issue 1, 1999, Pages 166-172

  Byrem, Todd M ^a   Booren, Alden M ^a   Hill, Gretchen M ^b   Chu, Fun Sun ^c   Strasburg, Gale M ^a  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Cyclopiazonic acid; Meat quality; Pi train; Pigs

Indexed keywords

ANIMALIA; SUIDAE; SUS SCROFA;

CYCLOPIAZONIC ACID; INDOLE DERIVATIVE; MYCOTOXIN;

ANIMAL; ANIMAL DISEASE; ANIMAL FOOD; ANIMAL HUSBANDRY; ARTICLE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD INDUSTRY; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; MALIGNANT HYPERTHERMIA; MEAT; METHODOLOGY; MUSCLE DEVELOPMENT; PATHOPHYSIOLOGY; SKELETAL MUSCLE; SWINE; SWINE DISEASE;

ANIMAL FEED; ANIMAL HUSBANDRY; ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOOD INDUSTRY; GENOTYPE; INDOLES; MALIGNANT HYPERTHERMIA; MEAT; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; MYCOTOXINS; SWINE; SWINE DISEASES;

EID: 0032602616     PISSN: 00218812     EISSN: None     Source Type: Journal    
DOI: 10.2527/1999.771166x     Document Type: Article

References (24)

1. Bendall, J. R. 1973. Post-mortem changes in muscle. In: G. H. Bourne (Ed.) The Structure and Function of Muscle (2nd Ed.). pp 243-309. Academic Press, London.
2. Byrem, T. M., J. J. Pestka, F. S. Chu, and G. M. Strasburg. 1998. Analysis and pharmacokinetics of cyclopiazonic acid in market weight pigs. J. Anim. Sci. 76:173-179.
3. De Smet, S. M., H. Pauwels, S. De Bie, D. I. Demeyer, J. Callewier, and W. Eeckhout. 1996. Effect of halothane genotype, breed, feed withdrawal, and lairage on pork quality of Belgian slaughter pigs. J. Anim. Sci. 74:1854-1863.
4. 2+ pump of skinned fibers from frog skeletal muscle. Eur. J Physiol. 429:169-175.
5. Fujii, J., K. Otsu, F. Zorzato, S. De Leon, V. K. Khanna, J. E. Wells, P. J. O'Brien, and D. H. MacLennan. 1991. Identification of a mutation in porcine ryanodine receptor associated with malignant hyperthermia. Science (Wash DC) 253:448-450.
6. Hermansen, K., J. C. Frisvad, C. Emborg, and J. Hansen. 1984. Cyclopiazonic acid production by submerged cultures of Penicillium and Aspergillus strains. FEMS Microbiol. Lett. 21: 253-261.
7. Holzapfel, C. W. 1968. The isolation and structure of cyclopiazonic acid, a toxic metabolite of Penicillium cyclopium Westling. Tetrahedron 24:2101-2119.
8. 2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes. Circ. Res. 73:820-828.
9. 2+-activated tension production in skinned skeletal muscle fibers of the ferret. Eur. J. Pharmacol. 241:41-46.
10. 2+ regulation defects. Physiol. Rev. 76:537-591.
11. Mount, L. E. 1979. Adaptation to Thermal Environment: Man and His Productive Animals. Edward Arnold, London.
12. Murray, A. C., S.D.M. Jones, and A. P. Sather. 1989. The effect of preslaughter feed restriction and genotype for stress susceptibility on pork lean quality and composition. Can. J. Anim. Sci. 69:83-91.
13. 14C]cyclopiazonic acid in rats. Food Chem. Toxicol. 23: 1069-1076.
14. NRC. 1981. Effects of Environment on Nutrient Requirements of Domestic Animals. National Academy Press, Washington, DC.
15. Offer, G. 1991. Modeling of the formation of pale, soft and exudative meat: Effects of chilling regime and rate and extent of glycolysis. Meat Sci. 30:157-184.
16. Pommier, S. A., and A. Houde. 1993. Effect of the genotype for malignant hyperthermia as determined by a restriction endonuclease assay on the quality characteristics of commercial pork loins. J. Anim. Sci. 71:420-425.
17. Potthast, K., and R. Hamm. 1976. The biochemistry of DFD-meat. Fleischwirtschaft 56:978-991.
18. SAS. 1985. SAS User's Guide: Statistics. SAS Inst. Inc., Cary, NC.
19. 2+-ATPase of sarcoplasmic reticulum. J. Biol. Chem. 264:17816-17823.
20. Simpson, S. P., and A. J. Webb. 1989. Growth and carcass performance of British Landrace pigs heterozygous at the halothane locus. Anim. Prod. 49:503-509.
21. Urano, T., M. W. Trucksess, and J. Matusik. 1992. Liquid chromatographic determination of cyclopiazonic acid in corn and peanuts. J. Assoc. Off. Anal. Chem. 75:319-322.
22. Voss, K. A. 1990. In vivo and in vitro toxicity of cyclopiazonic acid (CPA). Biodeterior. Res. 3:67-84.
23. Webb, A. J., and S. P. Simpson. 1986. Performance of British Landrace pigs selected for high and low incidence of halothane sensitivity. 2. Growth and carcass traits. Anim. Prod. 43: 493-503.
24. Widiastuti, R., R. Maryam, B. J. Blaney, and D. R. Stoltz. 1988. Cyclopiazonic acid in combination with aflotoxins, zearalenone and ochratoxin A in Indonesian corn. Mycopathologia 104: 153-156.