Are the current bioequivalence standards sufficient for the acceptance of narrow therapeutic index drugs? Utilization of a computer simulated warfarin bioequivalence model.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques

Volumn 2, Issue 1, 1999, Pages 15-22

  Walker, S E ^a   Friesen, M H ^a  

^a SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; WARFARIN;

AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; BIOLOGICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; CROSSOVER PROCEDURE; DRUG THERAPY; HUMAN; MONTE CARLO METHOD; PHARMACOKINETICS; STANDARD;

ANTICOAGULANTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; COMPUTER SIMULATION; CROSS-OVER STUDIES; DRUG THERAPY; HUMANS; MODELS, BIOLOGICAL; MONTE CARLO METHOD; THERAPEUTIC EQUIVALENCY; WARFARIN;

EID: 0032600426     PISSN: None     EISSN: 14821826     Source Type: Journal    
DOI: None     Document Type: Article

References (0)