Further development of a versatile microscale automated workstation for parallel adaptive experimentation

Laboratory Robotics and Automation

Volumn 11, Issue 4, 1999, Pages 217-223

  Cork, David G ^a   Sugawara, Tohru ^a   Lindsey, Jonathan S ^b   Corkan, L Andrew ^c   Du, Hai ^b  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c Scitec Lab Automation and Robotics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION SPECTROSCOPY; COMPUTER WORKSTATIONS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATERIALS HANDLING; SOLVENTS; STORAGE (MATERIALS);

PARALLEL ADAPTIVE EXPERIMENTATION; REACTOR BLOCKS; REAGENT/SAMPLE HANDLING; VERSATILE MICROSCALE WORKSTATIONS;

PROCESS CONTROL;

EID: 0032595154     PISSN: 08957533     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2728(1999)11:4<217::AID-LRA6>3.0.CO;2-C     Document Type: Article

References (7)

1. Sugawara, T.; Cork, D. G. Past and present development of automated synthesis apparatus for pharmaceutical chemistry at Takeda Chemical Industries. Lab Rob Autom 1996, 8, 221-230 and references therein.
2. Cork, D. G.; Kato, S.; Sugawara, T. Design and control of a non-robotic apparatus for syntheses using powdered reagents in an automated chemistry laboratory. Lab Rob Autom 1995, 7, 301-308.
3. (a) Du, H.; Corkan, L. A.; Yang, K.; Kuo, P. Y.; Lindsey, J. S. An automated microscale chemistry workstation capable of parallel, adaptive experimentation. Chemometrics and Intelligent Laboratory Systems, 1999 48, 181-203
4. (b) Kuo, P. Y.; Du, H.; Corkan, L. A.; Yang, K.; Lindsey, J. S. A planning module for performing factorial design and related combinatorial studies on an automated chemistry workstation. Chemometrics and Intelligent Laboratory Systems, 1999 48, 219-234
5. (c) Du, H.; Jindal, S.; Lindsey, J. S. Implementation of the multidirectional search algorithm in an automated chemistry workstation. A parallel yet adaptive approach for reaction optimization. Chemometrics and Intelligent Laboratory Systems, 1999 48, 235-256
6. (d) Du, H.; Shen, W.; Kuo, P. Y.; Lindsey, J. S. Decision-tree programs for an adaptive automated chemistry workstation: application to catalyst screening experiments. Chemometrics and Intelligent Laboratory Systems, 1999 48, 205-2217.
7. Lindsey, J. S.; Corkan, L. A. Toward high-performance parallel experimentation machines. Use of a scheduler as a quantitative computer-aided design tool for evaluating workstation performance. Chemometrics and Intelligent Laboratory Systems: Lab Inf Mgt 1993, 21, 139-150.