Botzinger-complex, bulbospinal expiratory neurones monosynaptically inhibit ventral-group respiratory neurones in the decerebrate rat

Experimental Brain Research

Volumn 124, Issue 2, 1999, Pages 173-180

  Tian, Guo Feng ^a   Peever, John H ^a   Duffin, James ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Botzinger complex; Bulbospinal expiratory neurones; Decerebrate rat; Intracellular recording; Respiration; Spike triggered averaging; Ventral group respiratory neurones

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DECEREBRATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MOTONEURON; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC INHIBITION; VAGOTOMY; ACTION POTENTIAL; ANIMAL; BREATHING; CYTOLOGY; ELECTROPHYSIOLOGY; MEDULLA OBLONGATA; NERVE CELL INHIBITION; PATHOPHYSIOLOGY; PHRENIC NERVE; PHYSIOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

ACTION POTENTIALS; ANIMALS; DECEREBRATE STATE; ELECTROPHYSIOLOGY; MALE; MEDULLA OBLONGATA; MOTOR NEURONS; NEURAL INHIBITION; PHRENIC NERVE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; SPINAL CORD;

EID: 0032589729     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002210050612     Document Type: Article

References (39)

1. Ballantyne D, Richter DW (1984) Post-synaptic inhibition of bulbar inspiratory neurones in the cat. J Physiol 348:67-87
2. Ballantyne D, Richter DW (1986) The non-uniform character of expiratory synaptic activity in expiratory bulbospinal neurones of the cat. J Physiol 370:433-456
3. Barillot JC, Grelot L, Reddad S, Bianchi AL (1990) Discharge patterns of laryngeal motoneurones in the cat: an intracellular study. Brain Res 509:99-106
4. Bianchi AL, Barillot JC (1982) Respiratory neurons in the region of the rectrofacial nucleus: pontile, medullary, spinal and vagal projections. Neurosci Lett 31:277-282
5. Bieger D, Hopkins DA (1987) Viscerotopic representation of the upper alimentary tract in the medulla oblongata in the rat: the nucleus ambiguus. J Comp Neurol 262:546-562
6. Bryant TH, Yoshida S, De Castro D, Lipski J (1993) Expiratory neurons of the Botzinger complex of the rat: a morphological study following intracellular labelling with biocytin. J Comp Neurol 335:267-282
7. Davies JGM, Kirkwood PA, Sears TA (1985a) The detection of monosynaptic connections from inspiratory bulbospinal neurones to inspiratory motoneurones in the cat. J Physiol 368:3362
8. Davies JGM, Kirkwood PA, Sears TA (1985b) The distribution of monosynaptic connections from inspiratory bulbospinal neurones to inspiratory motoneurones in the cat. J Physiol 368:63-87
9. Dobbins EG, Feldman JL (1994) Brainstem network controlling descending drive to phrenic motoneurons in rat. J Comp Neurol 347:64-86
10. Duffin J, Alphen J van (1995a) Bilateral connections from ventral group inspiratory neurons to phrenic motoneurons in the rat determined by cross-correlation. Brain Res 694:55-60
11. Duffin J, Alphen J van (1995b) Cross-correlation of augmenting expiratory neurons of the Botzinger complex in the cat. Exp Brain Res 103:251-255
12. Duffin J, Douse MA (1993) Bötzinger expiratory neurones inhibit propriobulbar decrementing inspiratory neurones. Neuroreport 4:1215-1218
13. Duffin J, Ezure K, Lipski J (1995) Breathing rhythm generation: focus on the rostral ventrolateral medulla. NIPS 10:133-140
14. Ellenberger HH, Feldman JL (1990) Subnuclear organization of the lateral tegmental field of the rat. I. Nucleus ambiguus and ventral respiratory group. J Comp Neurol 294:202-211
15. Ezure K, Manabe M (1988) Decrementing expiratory neurons of the Bötzinger complex. II. Direct inhibitory synaptic linkage with ventral respiratory group neurons. Exp Brain Res 72:159-166
16. Ezure K, Manabe M, Yamada H (1988) Distribution of medullary respiratory neurons in the rat. Brain Res 455:262-270
17. Fedorko L, Merrill EG (1984) Axonal projections from the rostral expiratory neurones of the Botzinger complex to medulla and spinal cord in the cat. J Physiol 350:487-496
18. Fedorko L, Duffin J, England SJ (1989a) Inhibition of inspiratory neurons of the nucleus retroambigualis by expiratory neurons of the Botzinger complex in the cat. Exp Neurol 106:74-77
19. Fedorko L, Hoskin RW, Duffin J (1989b) Projections from inspiratory neurons of the nucleus retroambigualis to phrenic motoneurons in the cat. Exp Neurol 105:306-310
20. Gdovin MJ, Knuth SL, Bartlett D Jr (1994) Respiratory motor nerve activities during spontaneous bladder contractions. J Appl Physiol 77:1349-1354
21. Grélot L, Bianchi AL, Iscoe S, Remmers JE (1988) Expiratory neurones of the rostral medulla: anatomical and functional correlates. Neurosci Lett 89:140-145
22. Jiang C, Lipski J (1990) Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Botzinger complex in the cat. Exp Brain Res 81:639-648
23. Merrill EG, Fedorko L (1984) Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Botzinger neurons. J Neurosci 4:2350-2353
24. Merrill EG, Lipski J (1987) Inputs to intercostal motoneurons from ventrolateral medullary respiratory neurons in the cat. J Neurophysiol 57:1837-1853
25. Merrill EG, Lipski J, Kubin L, Fedorko L (1983) Origin of the expiratory inhibition of nucleus tractus solitarius inspiratory neurones. Brain Res 263:43-50
26. Morillo AM, Núñez-Abades PA, Gaytán SP, Pásaro R (1995) Brain stem projections by axonal collaterals to the rostral and caudal ventral respiratory group in the rat. Brain Res Bull 37:205-211
27. Núñez-Abades PA, Pasaro R, Bianchi AL (1991) Localization of respiratory bulbospinal and propriobulbar neurons in the region of the nucleus ambiguus of the rat. Brain Res 568:165-172
28. Núñez-Abades PA, Morillo AM, Pasaro R (1993) Brainstem connections of the rat ventral respiratory subgroups: afferent projections. J Auton Nerv Sys 42:99-118
29. Otake K, Sasaki H, Ezure K, Manabe M (1988) Axonal projections from Bötzinger expiratory neurons to contralateral ventral and dorsal respiratory groups in the cat. Exp Brain Res 72:167-177
30. Richter D (1982) Generation and maintenance of the respiratory rhythm. J Exp Biol 100:93-107
31. Saether K, Hilaire G, Monteau R (1987) Dorsal and ventral respiratory groups of neurons in the medulla of the rat. Brain Res 419:87-96
32. Schwarzacher SW, Wilhelm Z, Anders K, Richter DW (1991) The medullary respiratory network in the rat. J Physiol 435:631-644
33. Tian G-F, Duffin J (1996) Spinal connections of ventral-group bulbospinal inspiratory neurons studied with cross-correlation in the decerebrate rat. Exp Brain Res 111:178-186
34. Tian G-F, Duffin J (1997) Synchronization of ventral-group, bulbospinal inspiratory neurons in the decerebrate rat. Exp Brain Res 117:479-487
35. Tian G-F, Peever JH, Duffin J (1998) Botzinger-complex expiratory neurons monosynaptically inhibit phrenic motoneurons in the decerebrate rat. Exp Brain Res 122:149-156
36. Woch G, Kubin L (1995) Non-reciprocal control of rhythmic activity in respiratory-modulated XII motoneurons. Neuroreport 6:2085-2088
37. Zheng Y, Barillot JC, Bianchi AL (1991) Patterns of membrane potentials and distributions of the medullary respiratory neurons in the decerebrate rat. Brain Res 546:261-270
38. Zheng Y, Barillot JC, Bianchi AL (1992a) Intracellular electrophysiological and morphological study of the medullary inspiratory neurons of the decerebrate rat. Brain Res 576:235-244
39. Zheng Y, Barillot JC, Bianchi AL (1992b) Medullary expiratory neurons in the decerebrate rat: an intracellular study. Brain Res 576:245-253