1H-NMR analysis of microbial-derived organic acids in primary root carious lesions and saliva

NMR in Biomedicine

Volumn 12, Issue 6, 1999, Pages 345-356

  Silwood, Christopher J L ^a   Lynch, Edward J ^b   Seddon, Sean ^b   Sheerin, Angela ^a   Claxson, Andrew W D ^a   Grootveld, Martin C ^a  

^a Inflammation Research Group   (United Kingdom)

^b St Bartholomews Roy London H ^*  (United Kingdom)

Author keywords

1H NMR; Carious dentin; Demineralization; Formic acid; Microbial derived organic acids; Primary root caries

Indexed keywords

CARBOXYLIC ACID; FORMIC ACID; LACTIC ACID; PERCHLORIC ACID; PROPIONIC ACID; ANION; PROTON;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ARTICLE; DEMINERALIZATION; DENTAL CARIES; DENTIN; PATHOGENESIS; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SALIVA ANALYSIS; AGED; CHEMISTRY; HUMAN; METABOLISM; METHODOLOGY; MICROBIOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SALIVA; TOOTH DISEASE;

AGED; ANIONS; CARBOXYLIC ACIDS; DENTIN; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; PERCHLORIC ACID; PROTONS; ROOT CARIES; SALIVA; TOOTH DEMINERALIZATION;

EID: 0032589425     PISSN: 09523480     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1492(199910)12:6<345::AID-NBM580>3.0.CO;2-C     Document Type: Article

References (36)

1. Traudt, M. and Kleinberg, I. Stoichiometry of oxygen consumption and sugar, organic acid and amino acid utilization in salivary sediment and pure cultures of oral bacteria. Arch. Oral Biol. 41, 967-978 (1996).
2. Gray, J. A. Kinetics of enamel dissolution during formation of incipient caries-like lesions. Arch. Oral Biol. 11, 397-421 (1966).
3. Featherstone, J. D. B. and Rodgers, B. E. Effect of acetic, lactic and other organic acids on the formation of artificial carious lesions. Caries Res. 15, 377-85 (1981).
4. Margolis, H. C. and Moreno, E. C. Composition of pooled plaque fluid from caries-free and caries-positive individuals following sucrose exposure. J. Dent. Res. 71, 1776-1784 (1992).
5. Vratsanos, S. M. Chromatographic microanalysis of organic acids in plaque related to food cariogenicity. In: Foods, Nutrition and Dental Health, Hefferen J. J., Ayer W. A., Koehler H. M., editors. (Volume 3), pp 89-91. Pathotox, Illinois (1981).
6. Vratsanos, S. M. and Mandel, I. D. Comparative plaque acidogenesis of caries-resistant vs. caries-susceptible adults. J. Dent. Res. 61, 465-468 (1982).
7. Edgar, W. M., Dodds, M. W. J. and Higham, S. M. Changes in carboxylic acid and free amino acid profiles in human dental plaque after a carbohydrate challenge in situ. Biochem. Soc. Trans. 14, 977 (1986).
8. Hojo, S., Takahashi, N. and Yamada, T. Acid profile in carious dentin. J. Dent. Res. 70, 182-186 (1991).
9. Hojo, S., Komatsu, M., Okuda, R., Takahashi, N. and Yamada, T. Acid profiles and pH of carious dentin in active and arrested lesions. J. Dent. Res. 73, 1853-1857 (1994).
10. Tyler, J. E. Quantitative estimation of volatile fatty acids in carious enamel by gas chromatography of their methyl esters. J. Dent. Res. 50, 1189-1194 (1971).
11. Lambert, J. E. and Moss, C. W. Gas-liquid chromatography of short-chain fatty acids on Dexsil 300GC. J. Chromatogr. 74, 335-338 (1972).
12. Zero, D. T., Fu, J., Anne, K. M., Cassata, S. M., McCormack, S. M. and Gwinner, L. M. An inproved intra-oral enamel demineralization test model for the study of dental caries. J. Dent. Res. 71, 871-878 (1992).
13. Creanor, S. L., MacFarlane, T. W. F., Weetman, D. A. and Stephen, K. W. Microbiology and acid/anion profiles of enamel surface plaque from an in situ caries appliance. Caries Res. 20, 392-397 (1986).
14. Niederman, R., Buyle-Bodin, Y., Lu, B.-Y., Robinson, P. and Naleway, C. Short-chain carboxylic acid concentration in human gingival crevicular fluid. J. Dent. Res. 76, 575-579 (1997).
15. Bell, J. D., Brown, J. C. and Sadler, P. J. NMR studies of biofluids. NMR Biomed. 2, 246-256 (1989).
16. Grootveld, M., Sheerin, A., Atherton, M., Millar, A. D., Lynch, E. J., Blake, D. R. and Naughton, D. P. Applications of high resolution NMR analysis to the study of inflammatory diseases at the molecular level. In: Biomedical Applications of Spectroscopy, Advances in Spectroscopy (Volume 25), Clark, R. J. H. and Hester, R. E., editors, pp. 295-237. John Wiley, Chichester (1996).
17. Beighton, D., Lynch, E. and Heath, M. R. A microbiolgical study of primary root-caries lesions with different treatment needs. J. Dent. Res. 72, 623-629 (1993).
18. Beighton, D., Smith, K. and Hayday, H. The growth of bacteria and the production of exoglycosidic enzymes in the dental plaque of macaque monkeys. Arch. Oral Biol. 31, 829-835 (1986).
19. Lynch, E. and Beighton, D. A comparison of primary root caries lesions classified according to colour. Caries Res. 28, 233-239 (1994).
20. Braunschweiler, L. and Ernst, R. R. Coherence transfer by isotropic mixing - application to proton correlation spectroscopy. J. Magn. Reson. 53, 521-528 (1983).
21. Bax, A. and Davis, D. G. MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy. J. Magn. Reson. 65, 355-360 (1985).
22. Jenkins, G. N., Saliva. The Physiology and Biochemistry of the Mouth, 4th edition. 295 pp. Blackwell Scientific, Oxford (1978).
23. Serum. In Geigy Scientific Tables, Lentner, C., editor (Volume 3), 8th edition, pp. 141. Ciba-Geigy., Bas (1988).
24. Martell, A. E. and Motekaitis, R. J. The Determination and Use of Stability Constants. VCH, Weinheim (1988).
25. 2). Free Rad. Res. 26, 209-234 (1997).
26. Dirksen, T. R. Little, M. F. and Bibby, B. G. The pH of carious cavities - II. The pH at different depths in isolated cavities. Arch. Oral Biol. 8, 91-97 (1963).
27. Singer, D. L. and Kleinberg, I. The free amino acids in human dental plaque. Arch. Oral Biol. 28, 873-878 (1983).
28. Bell, J. D., Brown, J. C. C., Nicholson, J. K. and Sadler, P. J. Assignment of resonances for 'acute-phase' glycoproteins in high resolution proton NMR spectra of human blood plasma. FEBS Lett. 215(2), 311-315 (1987).
29. Minah, G. E. and Loesche, W. J. Sucrose metabolism by prominent members of the flora isolated from cariogenic and non-cariogenic dental plaques. Infect. Immun. 17, 55-61 (1977).
30. Edwardsson, S. Bacteriological studies on deep areas of carious dentine. Odontol. Rev. 25(Suppl. 32), 1-143 (1974).
31. Distler, W. and Kroncke, A. Acid formation by mixed cultures of dental plaque bacteria Actinomyces and Veillonella. Arch. Oral Biol. 26, 123-126 (1981).
32. Carlsson, J. and Griffith, C. J. Fermentation products and bacterial yields in glucose-limited and nitrogen-limited cultures of streptococci. Arch. Oral Biol. 19, 1105-1109 (1974).
33. Calandra, J. and Adams, E. C. Oxidation of glucose degradation products in the presence of saliva and possible relation to caries immunity. J. Dent. Res. 40, 229-234 (1951).
34. Higham, S. M. and Edgar, W. M. Effects of lactate dehydrogenase and nicotinamide adenine dinucleotide on human dental plaque pH and acid anion concentrations. Arch. Oral Biol. 40, 55-59 (1995).
35. Hoshino, E., Karino, H. and Yamada, T. Lactate metabolism by human dental plaque and Veillonella under aerobic and anaerobic conditions. Arch. Oral Biol. 26, 17-22 (1981).
36. Guerrant, G. O., Lambert, M. A. and Moss, C. W. Analysis of short-chain acids from anaerobic bacteria by high performance liquid chromatography. J. Clin. Microbiol. 16, 355-360 (1982).