Vitamin B12 deficiency: A new risk factor for breast cancer?

Nutrition Reviews

Volumn 57, Issue 8, 1999, Pages 250-253

  Choi, Sang Woon ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; DIHYDROFOLIC ACID; DNA; FOLIC ACID; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TETRAHYDROFOLIC ACID;

BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DNA METHYLATION; ERYTHROPOIESIS; FAT INTAKE; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; ONCOGENE; PERNICIOUS ANEMIA; POSTMENOPAUSE; REVIEW; ANIMAL; BLOOD; BREAST TUMOR; GENETICS; METABOLISM; PROSPECTIVE STUDY; RISK FACTOR;

ANIMALS; BREAST NEOPLASMS; FEMALE; HUMANS; POSTMENOPAUSE; PROSPECTIVE STUDIES; RISK FACTORS; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 0032589416     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1753-4887.1999.tb06952.x     Document Type: Review

References (19)

1. Landis SH, Murray T, Bolden S, et al. Cancer statistics, 1999. CA Cancer J Clin 1999;49:8-31
2. Snyderwine EG. Diet and mammary gland carcinogenesis. In: Senn HJ, Gelber RD, Goldhirsch A, et al, eds. Recent results in cancer research. Berlin: Springer-Verlag, 1998;3-10
3. Stoll BA. Breast cancer and the Western diet: role of fatty acids and antioxidant vitamins. Eur J Cancer 1998;34:1852-6
4. 6) and breast cancer. Cancer Epidemiol Biomarkers Prev 1999;8:209-17
5. Massey BW, Rubin CE. The stomach in pernicious anemia: a cytologic study. Am J Med Sci 1954;481-92
6. 12 Report of a preliminary randomized, double-blind intervention trial. JAMA 0988;259:1525-30
7. 12 in heavy smokers. Chest 1994;106: 496-9
8. 12 and folate in carcinogenesis. Adv Exp Med Biol 1986;206:293-311
9. 12. In: Shils ME, Olson JA, Shike M, eds. Modern nutrition in health and disease, 8th ed. Malvern: Lea & Febiger, 1994;402-25
10. Kim YI. Folate and carcinogenesis: evidence, mechanisms, and implications. J Nutr Biochem 1999;10:66-88
11. 12, homocysteine status and DNA damage in young Australian adults. Carcinogenesis 1998;19:1163-71
12. Counts JL, Goodman JI. Hypomethylation of DNA: an epigenetic mechanism involved in tumor promotion. Mol Carcinog 1994;11:185-8
13. Soares J, Pinto AE, Cunha CV, et al. Global DNA hypomethylation in breast carcinoma. Correlation with prognostic factors and tumor progression. Cancer 1999;85:112-8
14. Dobrovic A, Simpfendorfer D. Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res 1997;57:3347-50
15. Kim YI, Pogribny IP, Basnakian AG, et al. Folate deficiency in rats induces DNA strand breaks and hypomethylation within p53 tumor suppressor gene. Am J Clin Nutr 1997;65:46-52
16. Graham S, Hellmann R, Marshall J, et al. Nutritional epidemiology of postmenopausal breast cancer in western New York. Am J Epidemiol 1991;134:552-66
17. Zhang S, Hunter DJ, Hankinson SE, et al. A prospective study of folate intake and the risk of breast cancer. JAMA 1999;281:1632-7
18. Lashner BA, et al. Red blood cell folate is associated with the development of dyaplasia and cancer in ulcerative colitis. J Cancer Res Clin Oncol 1993;119:549-54
19. Ma J, Stampfer MJ, Giovannucci E, et al. Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 1997;57:1098-102