Preparation of [186Re]Re-DMSA and its bio-distribution studies

Applied Radiation and Isotopes

Volumn 51, Issue 1, 1999, Pages 43-49

  Kothari, K ^a   Pillai, M R A ^a   Unni, P R ^a   Shimpi, H H ^b   Noronha, O P D ^b   Samuel, A M ^b  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b TATA MEMORIAL HOSPITAL   (India)

Author keywords

[No Author keywords available]

Indexed keywords

PROBENECID; RADIOPHARMACEUTICAL AGENT; RHENIUM 186; STANNOUS CHLORIDE; SUCCIMER RH 186; SUCCIMER TC 99M; UNCLASSIFIED DRUG; CHELATING AGENT; DIAGNOSTIC AGENT; ORGANOMETALLIC COMPOUND; RADIOISOTOPE; RHENIUM; RHENIUM(V)DIMERCAPTOSUCCINIC ACID; SUCCIMER; TIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG STABILITY; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RADIOISOTOPE DISTRIBUTION; RAT; TISSUE DISTRIBUTION; ANIMAL; CHEMISTRY; ISOTOPE LABELING; METHODOLOGY; SYNTHESIS; WISTAR RAT;

ANIMALS; CHELATING AGENTS; HYDROGEN-ION CONCENTRATION; ISOTOPE LABELING; MALE; ORGANOMETALLIC COMPOUNDS; RADIOISOTOPES; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; RHENIUM; SUCCIMER; TIN COMPOUNDS; TISSUE DISTRIBUTION;

COMPLEXATION; PH EFFECTS; REDUCTION; RHENIUM; TIN COMPOUNDS;

BIODISTRIBUTION; TIN CHLORIDE;

RADIOISOTOPES;

EID: 0032588786     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8043(98)00194-8     Document Type: Article

References (15)

1. 186Re )rhenium (V)-dimercaptosuccinic acid a possible tumour radiotherapy agent Appl. Radiat. Isot. 42:1991;167.
2. 188Re (V)DMSA) for targeted radiotherapy: Synthesis and preliminary animal studies Eur. J. Nucl. Med. 25:1998;613.
3. 99mTc (V)-DMSA for tumour and metastasis scintigraphy Nucl. Med. Biol. 19:1992;825.
4. 188Re (V)-DMSA revisited: Preparation and biodistribution of a potential radiotherapeutic agent with low kidney uptake Nucl. Med. Commun. 19:1997;173.
5. 99mTc -DMSA J. Nucl. Med. 15:1974;743.
6. Houston S., Allen S.J., Lazarus C.R., Reghebi K., Blower P.J., Singh J., Rubens R.D., Clarke S.E.M. Modifying renal uptake of pentavalent technetium-99m-DMSA and pentavalent rhenium-186-DMSA offers potential for tumour targeted radiotherapy of medullary thyroid carcinoma (MTC). Nucl. Med. Commun. 13:1992;211.
7. 186Re complexes of dimercaptosuccinic acid and hydroxy ethylidine diphosphonate. In: Book of Abstracts of the International Symposium on Modern Trends in Radiopharmaceuticals for Diagnosis and Therapy, pp. 94-95.
8. Mausner L.F., Srivastava S.C. Selection of radionuclides for radioimmunotherapy. Med. Phys. 20:1993;503.
9. Ohta H., Yamamoto K., Endo K.et al. A new imaging agent for medullary carcinoma of the thyroid. J. Nucl. Med. 25:1984;323.
10. 99mTc (V)-DMSA complex: Studies in medullary carcinoma of thyroid Nucl. Med. Commun. 12:1987;623.
11. 2 DMSA=meso-2,3-dimercaptosuccinic acid). J. Chem. Soc. Chem. Commun. 16, 1115.
12. 186Re ]-pentavalent dimercaptosuccinic acid complex Nucl. Med. Commun. 14:1993;197.
13. Watkinson J.C., Lazarus C.R., Mistry R., Shaheen O.H., Maisey M.N., Clarke S.E.M. Technetium-99m(V)-dimercaptosuccinic acid uptake in patients with head and neck squamous carcinoma: Experience in imaging. J. Nucl. Med. 30:1989;174.
14. 99mTc (V)-DMSA) Int. J. Appl. Radiat. Isot. 36:1985;311.
15. Yen T.C., King K.L., Yang A.H., Liu R.S., Yeh S.H. Comparative radionuclide imaging of metastatic insular carcinoma of the thyroid: Value of technetium-99m-(V)DMSA. J. Nucl. Med. 37:1996;78.